1,832 research outputs found
New results for virial coefficients of hard spheres in D dimensions
We present new results for the virial coefficients B_k with k <= 10 for hard
spheres in dimensions D=2,...,8.Comment: 10 pages, 5 figures, to appear in conference proceedings of STATPHYS
2004 in Pramana - Journal of Physic
Molecular and immunological characterization of profilin from mugwort pollen
In late summer in Europe, pollen of mugwort is one of the major sources of atopic allergens. No information about the complete molecular structure of any mugwort allergen has been published so far. Here we report the isolation and characterization of mugwort pollen cDNA clones coding for two isoforms of the panallergen profilin. Thirtysix percent of the mugwort allergic patients tested displayed IgE antibodies against natural and recombinant profilin, and no significant differences were observed in the IgEbinding properties of the isoforms. One profilin isoform was purified to homogeneity and detailed structural analysis indicated that the protein exists in solution as dimers and tetramers stabilized by sulfydryl and/or ionic interactions. Profilin monomers were detectable only after exposure of multimers to harsh denaturing conditions. Dimers and tetramers did not significantly differ in their ability to bind serum IgE from mugwort pollenallergic patients. However, oligomeric forms might have a higher allergenic potential than monomers because larger molecules would have additional epitopes for IgEmediated histamine release. Profilin isolated from mugwort pollen also formed multimers. Thus, oligomerization is not an artifact resulting from the recombinant production of the allergen. Inhibition experiments showed extensive IgE crossreactivity of recombinant mugwort profilin and profilin from various pollen and food extracts
Scattering properties of a cut-circle billiard waveguide with two conical leads
We examine a two-dimensional electron waveguide with a cut-circle cavity and
conical leads. By considering Wigner delay times and the Landauer-B\"{u}ttiker
conductance for this system, we probe the effects of the closed billiard energy
spectrum on scattering properties in the limit of weakly coupled leads. We
investigate how lead placement and cavity shape affect these conductance and
time delay spectra of the waveguide.Comment: 18 pages, 11 figures, accepted for publication in Phys. Rev. E (Jan.
2001
Properties of planetary fluids at high pressure and temperature
In order to derive models of the interiors of Uranus, Neptune, Jupiter and Saturn, researchers studied equations of state and electrical conductivities of molecules at high dynamic pressures and temperatures. Results are given for shock temperature measurements of N2 and CH4. Temperature data allowed demonstration of shock induced cooling in the the transition region and the existence of crossing isotherms in P-V space
Distinct domains of erythroid Kruppel-like factor modulate chromatin remodeling and transactivation at the endogenous beta-globin gene promoter
Characterization of the mechanism(s) of action of trans-acting factors in higher eukaryotes requires the establishment of cellular models that test their function at endogenous target gene regulatory elements. Erythroid Kruppel-like factor (EKLF) is essential for beta -globin gene transcription. To elucidate the in vivo determinants leading to transcription of the adult beta -globin gene, functional domains of EKLF were examined in the context of chromatin remodeling and transcriptional activation at the endogenous locus. Human EKLF (hEKLF) sequences, linked to an estrogen-responsive domain, were studied with an erythroblast cell line lacking endogenous EKLF expression (J2e Delta eklf). J2e Delta eklf cells transduced with hEKLF demonstrated a dose-dependent rescue of beta -globin transcription in the presence of inducing ligand. Further analysis using a series of amino-terminal truncation mutants of hEKLF identified a distinct internal domain, which is sufficient for transactivation. Interestingly, studies of the chromatin structure of the beta -promoter revealed that a smaller carboxy-terminal domain generated an open promoter configuration. In vitro and in vivo binding studies demonstrated that this region interacted with BRG1, a component of the SWI/SNF chromatin remodeling complex. However, further study revealed that BRG1 interacted with an even smaller domain of EKLF, suggesting that additional protein interactions are required for chromatin remodeling at the endogenous beta -promoter. Taken together, our findings support a stepwise process of chromatin remodeling and coactivator recruitment to the beta -globin promoter in vivo. The J2e Delta eklf inducible hEKLF system will be a valuable tool for further characterizing the temporal series of events required for endogenous beta -globin gene transcription
Ninth and Tenth Order Virial Coefficients for Hard Spheres in D Dimensions
We evaluate the virial coefficients B_k for k<=10 for hard spheres in
dimensions D=2,...,8. Virial coefficients with k even are found to be negative
when D>=5. This provides strong evidence that the leading singularity for the
virial series lies away from the positive real axis when D>=5. Further analysis
provides evidence that negative virial coefficients will be seen for some k>10
for D=4, and there is a distinct possibility that negative virial coefficients
will also eventually occur for D=3.Comment: 33 pages, 12 figure
Classical and quantum chaos in a circular billiard with a straight cut
We study classical and quantum dynamics of a particle in a circular billiard
with a straight cut. This system can be integrable, nonintegrable with soft
chaos, or nonintegrable with hard chaos, as we vary the size of the cut. We use
a quantum web to show differences in the quantum manifestations of classical
chaos for these three different regimes.Comment: LaTeX2e, 8 pages including 3 Postscript figures and 4 GIF figures,
submitted to Phys. Rev.
Integrability and action operators in quantum Hamiltonian systems
For a (classically) integrable quantum mechanical system with two degrees of
freedom, the functional dependence of the
Hamiltonian operator on the action operators is analyzed and compared with the
corresponding functional relationship in
the classical limit of that system. The former is shown to converge toward the
latter in some asymptotic regime associated with the classical limit, but the
convergence is, in general, non-uniform. The existence of the function
in the integrable regime of a parametric
quantum system explains empirical results for the dimensionality of manifolds
in parameter space on which at least two levels are degenerate. The comparative
analysis is carried out for an integrable one-parameter two-spin model.
Additional results presented for the (integrable) circular billiard model
illuminate the same conclusions from a different angle.Comment: 9 page
Aharonov-Bohm effect and resonances in the circular quantum billiard with two leads
We calculate the conductance through a circular quantum billiard with two
leads and a point magnetic flux at the center. The boundary element method is
used to solve the Schrodinger equation of the scattering problem, and the
Landauer formula is used to calculate the conductance from the transmission
coefficients. We use two different shapes of leads, straight and conic, and
find that the conductance is affected by lead geometry, the relative positions
of the leads and the magnetic flux. The Aharonov-Bohm effect can be seen from
shifts and splittings of fluctuations. When the flux is equal to (h/2e) and the
angle between leads is 180 degree, the conductance tends to be suppressed to
zero in the low energy range due to the Aharonov-Bohm effect.Comment: LaTeX2e, 8 pages, 6 figures, submitted to Phys. Rev. B (Two
references added. A discussion on discrete symmetries removed.
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