567 research outputs found

    System Architecture for Low-Power Ubiquitously Connected Remote Health Monitoring Applications With Smart Transmission Mechanism

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    We present a novel smart transmission technique with seamless handoff mechanism to achieve ubiquitous connectivity using multiple on-chip radios targeting remote health monitoring applications. For the first time to the best of our knowledge, a system architecture for low-power ubiquitously connected multiparametric remote health monitoring system is proposed in this paper. The architecture proposed uses a generic adaptive rule engine for classifying the collected multiparametric data from patient and smartly transmit the data when only needed. The on-chip seamless handoff mechanism proposed aids for the ubiquitous connectivity with a very good energy savings by intelligent controlling of the multiple on-chip radios. The performance analysis of the proposed on-chip seamless handoff mechanism along with adaptive rule engine-based smart transmission mechanism achieves on an average of 50.39% of energy saving and 51.01% reduction in duty cycle of transmitter taken over 20 users compared with the continuous transmission. From the hardware complexity analysis made on the proposed seamless handoff controller and adaptive rule engine concludes that they require only 2082 CMOS transistors for real-time implementation

    In vitro cell culture of Charybdis congesta for enhanced production of secondary metabolites: Proscillaridin A, Scillaren A and Scilliroside

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    Callus cultures of Charybdis congesta were initiated in vitro and the effect of growth regulators was tested on callus growth and secondary metabolite production. Among several standard media formulated for use in the present study, MS and B5 were found to be potentially active and facilitated the calculation of callus induction frequency (CIF). The CIF was higher in both MS (70%) and B5 (63%) media supplemented with 1-naphthalene acetic acid (NAA) (9.0 μM) and benzyl amino purine (BAP) (0.9 μM). However, with indole-3-butyric acid (IBA) (9.0 μM) and BAP (0.8 μM), less amount (22.6%) of CIF was observed in MS medium but no callus formation was noticed in B5 medium. Rapid high performance thin layer chromatography (HPTLC) screening of callus extracts revealed that the callus established in MS medium supplemented with 4.5 μM NAA and 0.46 μM BAP produced the highest yield of Proscillaridin A (4.51 mg/g DW), Scilliroside (3.3 mg/g DW), Scillaren A (2.35 mg/g DW) and desacetylscilliroside (8.62 mg/g DW), which was higher than from the intact plants. The results obtained indicate that the in vitro cultures of C. congesta might be an excellent source of secondary metabolites and further metabolic profiling may provide insights into up scaling of the compounds which lead to greater commercial interest and continuous supply of cultures.Keywords: Squill, Charybdis congesta, bufadienolides, callus cultures, reflectance scanning densitometryAfrican Journal of Biotechnology Vol. 12(15), pp. 1754-17

    CAPTURINGOF DIFFERENT PIXEL LOCATION OF COLOR IMAGES USING MVPC MEASURES

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    To produce video representation that separates it foreground and history without condition, we advise the spatial-temporal attention-aware pooling (STAP) framework. Inspired within the fact actions/foregrounds attract human visual attention, we advise to utilize it saliency to assist over it feature representation. Particularly, we advise an entirely new method of fuse the saliency maps from various saliency conjecture models. This new saliency model borrows the best understanding from existing saliency models that will reveal some visual semantics, e.g., face, moving objects, and so on.Existing STIP-based action recognition approaches operateon intensity representations inside the image data. Additionally, the end result show color STIPs are true only best low-level feature choice for STIP-based methods to human action recognition. Because ofthis, these approaches are conscious to disturbing photometricphenomena, for instance shadows and highlights. Additionally, valuableinformation is neglected by discarding chromaticity from thephotometric representation. We avoid gradient approximation based on integral video representations inside the partial derivatives. High-level methods for unconstrained human activity recognition goal at modeling image sequences while using the recognition of greater level concepts, and may develop low-level fundamental concepts. Color STIPs are multichannel reformulations of STIPdetectors and descriptors that people consider a numberof chromatic and invariant representations created from theopponent color space. Color STIPs happen to be proven to outperformtheir intensity-based counterparts over the challenging UCF sports, UCF11 and UCF50 action recognition benchmarks by more than5% typically, where most of the gain is a result of the multichanneldescriptors

    A rare case of indirect inguinal hernia with ovary as content at a hospital of Visakhapatnam

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    A hernia is the protrusion of the small intestines or omentum or other organs through a defect in the abdominal wall. Inguinal herniain females is very rare and occurs in <5% of women. Here, we report the case of a 25-year-old female who presented with swellingin the left groin associated with dragging pain in the left iliac fossa. She was investigated and diagnosed as a left indirect inguinalhernia. Hernioplasty was planned and intraoperatively ovary along with fimbria was identified as content. An inguinal ovary mayoccur if the gubernaculum fails to attach to the uterus in fetal life or if the canal of Nuck remains open after birth

    Abdominoperineal resection does not decrease quality of life in patients with low rectal cancer

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    PURPOSE: Issues related to body image and a permanent stoma after abdominoperineal resection may decrease quality of life in rectal cancer patients. However, specific problems associated with a low anastomosis may similarly affect quality of life for patients undergoing low anterior resection. The aim of this study was to compare quality of life of low rectal cancer patients after undergoing abdominoperineal resection versus low anterior resection. METHODS: Demographics, tumor and treatment characteristics, and prospectively collected preoperative quality-of-life data for patients undergoing low anterior resection or abdominoperineal resection for low rectal cancer between 1995 and 2009 were compared. Quality of life collected at specific time intervals was compared for the two groups, adjusting for age, body mass index, use of chemoradiation, and 30 days postoperative complications. The short-form-36 questionnaire was used to determine quality of life. RESULTS: The query returned 153 patients (abdominoperineal resection = 68, low anterior resection = 85) with a median follow-up of 24 (3-64) mo. The after abdominoperineal resection group had a higher mean age (63 + 12 vs. 54 + 12, p < 0.001) and more American Society of Anesthesiologists classification 3/4 patients (65 percent vs. 43 percent, p = 0.03) than low anterior resection. Other demographics, tumor stage, use of chemoradiation, overall postoperative complication rates, and quality-of-life follow-up time were not statistically different in both groups. Patients undergoing abdominoperineal resection had a lower baseline short-form-36 mental component score than those undergoing low anterior resection. However, 6 mo after surgery this difference was no longer statistically significant and essentially disappeared at 36 mo after surgery. CONCLUSION: Patients undergoing abdominoperineal resection for low rectal cancer have a similar long-term quality of life as those undergoing low anterior resection. These findings can help clinicians to better counsel patients with low rectal cancer who are being considered for abdominoperineal resection

    StemCellNet: an interactive platform for network-oriented investigations in stem cell biology.

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    Stem cells are characterized by their potential for self-renewal and their capacity to differentiate into mature cells. These two key features emerge through the interplay of various factors within complex molecular networks. To provide researchers with a dedicated tool to investigate these networks, we have developed StemCellNet, a versatile web server for interactive network analysis and visualization. It rapidly generates focused networks based on a large collection of physical and regulatory interactions identified in human and murine stem cells. The StemCellNet web-interface has various easy-to-use tools for selection and prioritization of network components, as well as for integration of expression data provided by the user. As a unique feature, the networks generated can be screened against a compendium of stemness-associated genes. StemCellNet can also indicate novel candidate genes by evaluating their connectivity patterns. Finally, an optional dataset of generic interactions, which provides large coverage of the human and mouse proteome, extends the versatility of StemCellNet to other biomedical research areas in which stem cells play important roles, such as in degenerative diseases or cancer. The StemCellNet web server is freely accessible at http://stemcellnet.sysbiolab.eu

    DRIVER CAUTION SYSTEM FOR SAFETY USING SMART LED DISPLAY BOARDS

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    To prevent accidents and also to alert the motorists concerning the speed limits such type of places the highway department have placed the signboards. Nowadays individuals are driving extremely fast, accidents are occurring frequently, we lost our valuable existence by looking into making small mistake while driving (zone wise, hillsides area, highways). But, May too easy to view that sort of signboards and there's a way for accident. To intimate the motive force concerning the posted speed limit at zones and also to identify crashes instantly, is completed by way of using MEMS, RF, Gps navigation, GSM technology. The primary objective would be to design a good Display controller intended for vehicle’s posted speed limit and crash alerts which could operate on an embedded system. Smart Display &amp; Control (SDC) could be custom-designed to suit right into a vehicle’s dashboard, and displays info on the automobile

    AN EMBEDDED DEVICE TO REGULATE AIR CIRCULATION IN HOT CONDITIONS IN A VEHICLE SYSTEM

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    Microcontroller controls the positioning of the home windows autonomously and individually from the driver’s presence, following predefined formula that utilizes sensors data acquired in the vehicle’s surroundings. The module is implemented utilizing a microcontroller like a central logical unit and a number of sensors which offer sufficient data to make sure functional, but additionally efficient, reliable and safe ventilation and safety of passengers. To be able to mitigate overheated interior of the vehicle parked within the hot summer time sun and therefore to help make the getting into the automobile much more comfortable, and stopping passengers from injuries when accident occurs, microcontroller managed module for automatic ventilation of car interior is created. The ventilation process is conducted by opening vehicle home windows slightly, which helps air to flow. Besides temperature, the most crucial factors to make sure quality implementation of ventilation are detected movements round the vehicle, the existence of humidity along with other. As well as microcontroller controls airbags position. This project uses controlled 5V, 500mA power. 7805 three terminal current regulator can be used for current regulation. Bridge type full wave rectifier can be used to rectify the ac creation of secondary of 230/12V step lower transformer. Using the vibration sensor data for enabling the environment bags open when accident happened towards the vehicle. This paper shows the constituents, their intention and abilities, pros and cons, in addition to potential implementations and upgrades. The exam results give understanding of utilization options of the module and it is effectiveness

    Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.

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    Essentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular timing mechanisms regulating important physiological processes, PPI dynamics on this timescale are largely unknown. Here, we identified 109 novel PPIs among circadian clock proteins via a yeast-two-hybrid approach. Among them, the interaction of protein phosphatase 1 and CLOCK/BMAL1 was found to result in BMAL1 destabilization. We constructed a dynamic circadian PPI network predicting the PPI timing using circadian expression data. Systematic circadian phenotyping (RNAi and overexpression) suggests a crucial role for components involved in dynamic interactions. Systems analysis of a global dynamic network in liver revealed that interacting proteins are expressed at similar times likely to restrict regulatory interactions to specific phases. Moreover, we predict that circadian PPIs dynamically connect many important cellular processes (signal transduction, cell cycle, etc.) contributing to temporal organization of cellular physiology in an unprecedented manner
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