Cross section of the Berkshire massif at 42 N.: Profile of a basement reactivation zone

Guidebook for field trips in western Massachusetts, northern Connecticut and adjacent areas of New York: 67th annual meeting October 10, 11, and 12, 1975: Trip B-6; C-

Letter: Faecal volatile organic metabolites, promising biomarkers in inflammatory bowel disease and Letter: Faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease. Authors' reply

The aetiology of inflammatory bowel disease (IBD) remains poorly understood. Recent evidence suggests an important role of gut microbial dysbiosis in IBD, and this may be associated with changes in faecal volatile organic metabolites (VOMs).To describe the changes in the faecal VOMs of patients with IBD and establish their diagnostic potential as non-invasive biomarkers.Faecal samples were obtained from 117 people with Crohn's disease (CD), 100 with ulcerative colitis (UC), and 109 healthy controls. Faecal VOMs were extracted using solid-phase micro-extraction and analysed by gas chromatography mass spectrometry. Data analysis was carried out using partial least squares-discriminate analysis (PLS-DA) to determine class membership based on distinct metabolomic profiles.The PLS-DA model showed clear separation of active CD from inactive disease and healthy controls (P < 0.001). Heptanal, 1-octen-3-ol, 2-piperidinone and 6-methyl-2-heptanone were up-regulated in the active CD group [variable important in projection (VIP) score 2.8, 2.7, 2.6 and 2.4, respectively], while methanethiol, 3-methyl-phenol, short-chain fatty acids and ester derivatives were found to be less abundant (VIP score of 3.5, 2.6, 1.5 and 1.2, respectively). The PLS-DA model also separated patients with small bowel CD from healthy controls and those with colonic CD from UC (P < 0.001). In contrast, less distinct separation was observed between active UC, inactive UC and healthy controls.Analysis of faecal volatile organic metabolites can provide an understanding of gut metabolomic changes in IBD. It has the potential to provide a non-invasive means of diagnosing IBD, and can differentiate between UC and CD

A study of the effects of acid on the polymerisation of pyrrole, on the oxidative polymerisation of pyrrole and on polypyrrole

The polymer products arising from the hydrochloric acid treatment of aqueous pyrrole were shown to have spectroscopic data consistent with alternating pyrrole and pyrrolidine units with varying degrees of ring opening of the pyrrole units. The acid catalysed polymerisation of pyrrole offers a facile route to polymers with amine and carbonyl functional groups, which could be further derivatised. The products were polydisperse spheres; however the use of steric stabilisers induced monodisperse sphere formation and a concomitant ten fold decrease in size. Dilute nitric acid treatment of aqueous pyrrole gave polydisperse spheres (and ovoid shapes) in lower yield, plus a small proportion of curious particles which resembled pitted olives. The presence of acid in the reaction mixture of pyrrole and ferric ions was shown to have a relatively small effect on the conductivity of the resultant polypyrrole. The ability of polypyrrole to withstand harsh acidic conditions was assessed. Polypyrrole was shown to possess significant conductivity even after treatment with boiling concentrated hydrochloric acid

Cosmological redshift distortion: deceleration, bias and density parameters from future redshift surveys of galaxies

The observed two-point correlation functions of galaxies in redshift space become anisotropic due to the geometry of the universe as well as due to the presence of the peculiar velocity field. On the basis of linear perturbation theory, we expand the induced anisotropies of the correlation functions with respect to the redshift $z$, and obtain analytic formulae to infer the deceleration parameter $q_0$, the density parameter $\Omega_0$ and the derivative of the bias parameter $d\ln b/dz$ at $z=0$ in terms of the observable statistical quantities. The present method does not require any assumption of the shape and amplitude of the underlying fluctuation spectrum, and thus can be applied to future redshift surveys of galaxies including the Sloan Digital Sky Survey. We also evaluate quantitatively the systematic error in estimating the value of $\beta_0 \equiv \Omega_0^{0.6}/b$ from a galaxy redshift survey on the basis of a conventional estimator for $\beta_0$ which neglects both the geometrical distortion effect and the time evolution of the parameter $\beta(z)$. If the magnitude limit of the survey is as faint as 18.5 (in B-band) as in the case of the Sloan Digital Sky Survey, the systematic error ranges between -20% and 10% depending on the cosmological parameters. Although such systematic errors are smaller than the statistical errors in the current surveys, they will dominate the expected statistical error for future surveys.Comment: 9 pages, 5 figs, aastex, ApJ in press, replaced version includes minor correction

Linking extreme interannual changes in prey availability to foraging behaviour and breeding investment in a marine predator, the macaroni penguin

Understanding the mechanisms that link prey availability to predator behaviour and population change is central to projecting how a species may respond to future environmental pressures. We documented the behavioural responses and breeding investment of macaroni penguins Eudyptes chrysolophus across five breeding seasons where local prey density changed by five-fold; from very low to highly abundant. When prey availability was low, foraging trips were significantly longer and extended overnight. Birds also foraged farther from the colony, potentially in order to reach more distant foraging grounds and allow for increased search times. These extended foraging trips were also linked to a marked decrease in fledgling weights, most likely associated with reduced rates of provisioning. Furthermore, by comparing our results with previous work on this population, it appears that lowered first-year survival rates associated, at least partially, with fledging masses were also evident for this cohort. This study integrates a unique set of prey density, predator behaviour and predator breeding investment data to highlight a possible behavioural mechanism linking perturbations in prey availability to population demography

‘Ethnic group’, the state and the politics of representation

The assertion, even if only by implication, that ‘ethnic group’ categories represent ‘real’ tangible entities, indeed identities, is commonplace not only in the realms of political and policy discourse but also amongst contemporary social scientists. This paper, following Brubaker (2002), questions this position in a number of key respects: of these three issues will dominate the discussion that follows. First, there is an interrogation of the proposition that those to whom the categories/labels refer constitute sociologically meaningful ‘groups’ as distinct from (mere) human collectivities. Secondly, there is the question of how these categories emerge, i.e. exactly what series of events, negotiations and contestations lie behind their construction and social acceptance. Thirdly, and as a corollary to the latter point, we explore the process of reification that leads to these categories being seen to represent ‘real things in the world’ (ibid.)

Drivers of intrapopulation variation in resource use in a generalist predator, the macaroni penguin

Intrapopulation variation in resource use occurs in many populations of generalist predators with important community and evolutionary implications. One of the hypothesised mechanisms for such widespread variation is ecological opportunity, i.e. resource availability determined by intrinsic constraints and extrinsic conditions. We combined tracking data and stable isotope analysis to examine how breeding constraints and prey conditions influenced intrapopulation variation in resource use among macaroni penguins Eudyptes chrysolophus. Isotopic variation was also examined as a function of breeding success, individual traits and individual specialisation. Variation in isotope ratios was greatest across multiple tissue types when birds were able to undertake mid-range foraging trips (i.e. during incubation and pre-moult). This variation was highly consistent between years that spanned a 3-fold difference in local krill Euphausia superba density and was also highly consistent at the individual level between 2 years that had similar krill densities. However, by comparing our results with previous work on the same population, it appeared that a decrease in local prey availability can increase intrapopulation variation in resource use during periods with more restricted foraging ranges (i.e. during brood-guard and crèche). This study highlights the importance of considering ecological interactions that operate on multiple spatio-temporal scales when examining the drivers of resource use in populations of generalist predators

Wave-particle interactions in non-uniform plasma and the interpretation of Hard X-ray spectra in solar flares

Context. High energy electrons accelerated during solar flare are abundant in the solar corona and in the interplanetary space. Commonly, the number and the energy of non-thermal electrons at the Sun is estimated using hard X-ray (HXR) spectral observations (e.g. RHESSI) and a single-particle collisional approximation. Aims. To investigate the role of the spectrally evolving Langmuir turbulence on the population of energetic electrons in the solar corona. Methods. We numerically simulate the relaxation of a power-law non-thermal electron population in a collisional inhomogeneous plasma including wave-particle, and wave-wave interactions. Results. The numerical simulations show that the long-time evolution of electron population above 20 keV deviates substantially from the collisional approximation when wave-particle interactions in non-uniform plasma are taken into account. The evolution of Langmuir wave spectrum towards smaller wavenumbers, due to large-scale density fluctuations and wave-wave interactions, leads to an effective acceleration of electrons. Furthermore, the time-integrated spectrum of non-thermal electrons, which is normally observed with HXR above 20 keV, is noticeably increased due to acceleration of non-thermal electrons by Langmuir waves. Conclusions. The results show that the observed HXR spectrum, when interpreted in terms of collisional relaxation, can lead to an overestimated number and energy of energetic electrons accelerated in the corona.Comment: 8 pages, 6 figures, submitted to Astronomy and Astrophysics Journa