Status consciousness in energy consumption: a systematic review

Access to energy is a precondition for a decent standard of living. Some household decisions on energy consumption are however motivated to maintain or improve status, resulting in social zero-sum games, with environmentally harmful outcomes. Here, we review evidence relating status to energy consumption, elucidating consequential opportunities for climate change mitigation. To achieve this, we comprehensively collate and analyse existing published work that links status to household consumption decisions and behaviour across all end-use sectors, screening 2662 papers found with systematic search queries, identifying and fully reviewing 53 papers that comply with our criteria. We develop a systematic map of the literature and review quantitative and qualitative analysis relating energy end-use to status consumption. We identify 23 distinct (albeit some of them closely related) theories, with the literature most frequently referring to Veblen’s theory of conspicuous consumption. We also detail estimations of status-related energy consumption and identify ten studies that quantitatively relate status to energy saving behaviour or decisions, and four studies that relate status to increased emissions. Status can explain up to 20% change in consumption levels or the willingness-to-pay for carbon reducing consumption. Surprisingly, we find that major status-related consumption decisions, such as for housing and big cars, are hardly captured by the literature that relates status consumption to energy use and greenhouse gas emissions. This is a considerable gap in the literature, omitting major sources of status related decisions with high carbon footprint. We conclude that framing energy saving behaviour as high status is a promising strategy for emission reduction. Progressive taxation of status items, such as floor space and vehicle size, can effectively internalize the positional externalities and signal social undesirability, but also reduce emissions

Common variants in CLDN2 and MORC4 genes confer disease susceptibility in patients with chronic pancreatitis

A recent Genome-wide Association Study (GWAS) identified association with variants in X-linked CLDN2 and MORC4 and PRSS1-PRSS2 loci with Chronic Pancreatitis (CP) in North American patients of European ancestry. We selected 9 variants from the reported GWAS and replicated the association with CP in Indian patients by genotyping 1807 unrelated Indians of Indo-European ethnicity, including 519 patients with CP and 1288 controls. The etiology of CP was idiopathic in 83.62% and alcoholic in 16.38% of 519 patients. Our study confirmed a significant association of 2 variants in CLDN2 gene (rs4409525—OR 1.71, P = 1.38 x 10-09; rs12008279—OR 1.56, P = 1.53 x 10-04) and 2 variants in MORC4 gene (rs12688220—OR 1.72, P = 9.20 x 10-09; rs6622126—OR 1.75, P = 4.04x10-05) in Indian patients with CP. We also found significant association at PRSS1-PRSS2 locus (OR 0.60; P = 9.92 x 10-06) and SAMD12-TNFRSF11B (OR 0.49, 95% CI [0.31–0.78], P = 0.0027). A variant in the gene MORC4 (rs12688220) showed significant interaction with alcohol (OR for homozygous and heterozygous risk allele -14.62 and 1.51 respectively, P = 0.0068) suggesting gene-environment interaction. A combined analysis of the genes CLDN2 and MORC4 based on an effective risk allele score revealed a higher percentage of individuals homozygous for the risk allele in CP cases with 5.09 fold enhanced risk in individuals with 7 or more effective risk alleles compared with individuals with 3 or less risk alleles (P = 1.88 x 10-14). Genetic variants in CLDN2 and MORC4 genes were associated with CP in Indian patients

Reviewing the scope and thematic focus of 100,000 publications on energy consumption, services and social aspects of climate change: a big data approach to demand-side mitigation

As current action remains insufficient to meet the goals of the Paris agreement let alone to stabilize the climate, there is increasing hope that solutions related to demand, services and social aspects of climate change mitigation can close the gap. However, given these topics are not investigated by a single epistemic community, the literature base underpinning the associated research continues to be undefined. Here, we aim to delineate a plausible body of literature capturing a comprehensive spectrum of demand, services and social aspects of climate change mitigation. As method we use a novel double-stacked expert—machine learning research architecture and expert evaluation to develop a typology and map key messages relevant for climate change mitigation within this body of literature. First, relying on the official key words provided to the Intergovernmental Panel on Climate Change by governments (across 17 queries), and on specific investigations of domain experts (27 queries), we identify 121 165 non-unique and 99 065 unique academic publications covering issues relevant for demand-side mitigation. Second, we identify a literature typology with four key clusters: policy, housing, mobility, and food/consumption. Third, we systematically extract key content-based insights finding that the housing literature emphasizes social and collective action, whereas the food/consumption literatures highlight behavioral change, but insights also demonstrate the dynamic relationship between behavioral change and social norms. All clusters point to the possibility of improved public health as a result of demand-side solutions. The centrality of the policy cluster suggests that political actions are what bring the different specific approaches together. Fourth, by mapping the underlying epistemic communities we find that researchers are already highly interconnected, glued together by common interests in sustainability and energy demand. We conclude by outlining avenues for interdisciplinary collaboration, synthetic analysis, community building, and by suggesting next steps for evaluating this body of literature

Entrepreneurship Ecosystem in GCC and India: A Perspective

The present study aims to identify the differences in the entrepreneurial ecosystems of GCC and India. Special attention is given to certain attributes and components within the ecosystems that make the individual ecosystems work. To compare the ecosystems of GCC and India, different databases were used to understand of the two regions and their entrepreneur ecosystems. The results indicate that the best feature of the GCC entrepreneurial ecosystem is its connection with the oil-based market, where GCC entrepreneurs benefit from numerous potentials and help the government. GCC Governments support entrepreneurs and initiate financing to explore business in foreign market. However, the best feature in their ecosystem is the physical and service infrastructure. In addition, cultural support for entrepreneurship is high in India. Nevertheless, the present research proposes proposing that this measurement is not representation for the actual situation. This analogy reflects an indication of both regions support to entrepreneurship and thereby providing an environment for ecosystems. The study recommends that future research should address the effect of cultural and political differences on measurement scores

Fair street space allocation: ethical principles and empirical insights

Urban street space is increasingly contested. However, it is unclear what a fair street space allocation would look like. We develop a framework of ten ethical principles and three normative perspectives on street space – streets for transport, streets for sustainability, and streets as place – and discuss 14 derived street space allocation mechanisms. We contrast these ethically grounded allocation mechanisms with real-world allocation in 18 streets in Berlin. We find that car users, on average, had 3.5 times more space available than non-car users. While some allocation mechanisms are more plausible than others, none is without disputed normative implications. All of the ethical principles, however, suggest that on-street parking for cars is difficult to justify, and that cycling deserves more space. We argue that ethical principles should be systematically integrated into urban and transport planning

Chronic Exposure to Chewing Tobacco Induces Metabolic Reprogramming and Cancer Stem Cell-Like Properties in Esophageal Epithelial Cells

Tobacco in its smoke and smokeless form are major risk factors for esophageal squamous cell carcinoma (ESCC). However, molecular alterations associated with smokeless tobacco exposure are poorly understood. In the Indian subcontinent, tobacco is predominantly consumed in chewing form. An understanding of molecular alterations associated with chewing tobacco exposure is vital for identifying molecular markers and potential targets. We developed an in vitro cellular model by exposing non-transformed esophageal epithelial cells to chewing tobacco over an eight-month period. Chronic exposure to chewing tobacco led to increase in cell proliferation, invasive ability and anchorage independent growth, indicating cell transformation. Molecular alterations associated with chewing tobacco exposure were characterized by carrying out exome sequencing and quantitative proteomic profiling of parental cells and chewing tobacco exposed cells. Quantitative proteomic analysis revealed increased expression of cancer stem cell markers in tobacco treated cells. In addition, tobacco exposed cells showed the Oxidative Phosphorylation (OXPHOS) phenotype with decreased expression of enzymes associated with glycolytic pathway and increased expression of a large number of mitochondrial proteins involved in electron transport chain as well as enzymes of the tricarboxylic acid (TCA) cycle. Electron micrographs revealed increase in number and size of mitochondria. Based on these observations, we propose that chronic exposure of esophageal epithelial cells to tobacco leads to cancer stem cell-like phenotype. These cells show the characteristic OXPHOS phenotype, which can be potentially targeted as a therapeutic strategy