Crystal and Molecular Structure of Sclerophytin F Methyl Ether from the Soft Coral Cladiella krempfi

new cembranoid diterpene was isolated from the soft coral Ckdiella h p f ifrom Minicoy Island (India), and its structure was established by X-ray crystallography to be sclerophytin F methyl ether (21 with the R absolute configuration at all six epimeric centers,assuming a configuration similar to that of sclerophytin C. Compound 2 may be an artifact of the isolation process

Synthesis of Pharma Europa Impurity-A of Flecainide Acetate

Synthesis of Pharma Europa Impurity-A of Flecainide Acetat

Resolution of racemic Vigabatrin using tartaric acid

<p>An efficient and simple resolution methodology for the preparation of (<i>S</i>)- and (<i>R</i>)-Vigabatrin has been developed. In addition, a method of preparation for the novel compounds Vigabatrin-l-tartarate and Vigabatrin-d-tartarate is also described. The title compounds have been synthesized via resolution of Vigabatrin using commercially available l-(+)- and d-(−)-tartaric acids respectively.</p