COMPREHENSIVE REVIEW OF KRIMIGHNA DRUGS MENTIONED IN THE AYURVEDIC PHARMACOPOEIA OF INDIA

Ayurveda is the science of life having wide description of Krimighna dravya in its literature. Ayurvedic pharmacopeia of India published by the Ministry of AYUSH is a monograph of single drugs; which is very popular for all stack holder of Ayush system of medicines. This article details the review of single drugs mentioned in API part I (Vol I to VI) and their screening for Krimighna (antimicrobial) properties. Present article also aims for validating classical fact with published scientific research work. Authors searched 54 drugs out of 519 single drugs described in the API & it was found most of Ayurvedic Krimighnadravya were recognized for having antimicrobial property which was established through various Preclinical & clinical work carried out by the scientific community. Authors collected data with references to validate API drugs having antimicrobial property. All screened content can be taken for various high-tech research work by various students in MD, PhD or in the various other project of CSIR, DST, EMR project of CCRAS for further development of new drugs and conversion of available drugs to latest dosage form

A COMPREHENSIVE REVIEW ON ADULTERATION OF RAW MATERIALS USED IN ASU DRUG MANUFACTURING

Ayurveda is a system of Indian traditional form of alternative medicine. In 20th and 21th century due to side effects of synthetic drugs, there is an increasing interesting ASU medicine. At present the adulteration of the herbal drugs is the burning problem in ASU herbal industry and it has caused a major problem in the research on commercial natural products. The deforestation and extinction of many species and incorrect identification of many plants has resulted in adulteration and substitution of raw drugs. The future development of analysis of herbs is largely depended upon reliable methodologies for correct identification, standardization and quality assurance of Ayurvedic drugs. In India normally the contamination/adulteration in food/crude drugs is done either for financial gain or due to carelessness and lack in proper hygienic condition of processing, storing, transportation and marketing. Medicinal plants constitute an effective source of traditional and modern medicine. Adulteration is considered as an intentional addition of foreign substances to increase the weight of the product or to decrease its cost. It may be due to- Confusion in vernacular names, Lack of knowledge about authentic plants, Non availability, Similarity in morphology, activity, aroma, Careless collection and other unknown reasons. This article throws a light on adulteration, types, common market adulterants in ASU medicines and prescribed Prevention methods

A REVIEW ON AYURVEDIC PROSPECTIVE AND CURATIVE HERBS FOR TYPE II DIABETES

Diabetes is a metabolic disorder which is affecting million people all over the world. Maharishi Charak described Prameharoga (20 types) ; and its one type is “Madhumeha ” having almost identical clinical feature of diabetes type II. Author taken detail review of available data for more than 2000 herbs and has collected various references/research work done by various scientist for pharmacological screening of anti-diabetic herbs through latest available In-vivo studies. And concluded 53 herbs have significant anti diabetic activity in different pharmacological in vivo model. Further for validation of modern research outcome authors had done extensive survey of most applicable herbal text book of Auyrveda“ Bhavprakash Nighantu” and Ayurvedic pharmacopeia of India part I volume I to VIII that has widely used by various stake holders of Ayurvedic industry, academia and students. Authors sorted about 25 Ayurvedic single drugs from reference mentioned above for their “Pramehaghna activity”. There is ample scope to trace out other single and compound drugs for cure of diabetes mellitus type II. Author’s also mentioned here some selected famous Ayurvedic compound and single drug that has been successfully used by Ayurvedic physicians in last 5 decades. Research community need to explore possibility to invent new drugs for management DM Type II like currently AYUSH 82(Developed by CCRAS & it has marketed in various trade name like right sugar, Diavit 82, DB6, IME 9) and BGR 34 (Developed by CSIR/NBRI) proven as very effective drug in the treatment of DM type II; hence research community of AYUSH system of medicines may explore the new era for NPD (new drug Development)