Dibutylchloro[4-(4-nitrophenyl)piperazine-1-carbodithioato-kappa S-2,S ']tin(IV)

The title complex, [Sn(C4H9)(2)(C11H12N3O2S2) Cl], features an asymmetrically chelating thiocarboxylate ligand. There are two molecules in the asymmetric unit. The Sn atom is five-coordinated within a C2ClS2 donor set that is best described as trigonal-bipyramidal with one S atom and the Cl atom in axial positions, subtending bond angles of 155.67 (2) and 155.11 (2)degrees, respectively

Chlorodiethyl[4-(4-nitrophenyl)piperazine-1-carbodithioato]tin(IV)

The molecule of the title compound, [Sn(C2H5)(2)(C11H12N3O2S2)Cl], features an asymmetrically chelating thiocarboxylate ligand. The Sn atom is five-coordinate within a C2ClS2 donor set that is best described as trigonal bipyramidal with S and Cl atoms in axial positions, defining a bond angle of 156.58 (2)degrees

How is Testing Related to Single Statement Bugs?

In this study, we analyzed the correlation between unit test coverage and the occurrence of Single Statement Bugs (SSBs) in open-source Java projects. We analyzed data from the top 100 Maven-based projects on GitHub, which includes 7824 SSBs. Our preliminary findings suggest a weak to moderate correlation, indicating that increased test coverage is somewhat reduce the occurrence of SSBs. However, this relationship is not very strong, emphasizing the need for better tests. Our study contributes to the ongoing discussion on enhancing software quality and provides a basis for future research into effective testing practices aimed at mitigating SSBs

Recycling of Steel Scraps as a Strength Enhancement Material in Concrete

The cement industry is very energy consumptive and produces CO2 and also generates greenhouse gases which are the major cause of global warming. The production of cement and the use of concrete are both rising daily. So, to protect the environment, alternate materials are required. The construction industry has several constructional byproducts and wastes as a variant of traditionally used products. In the process of production and working with steel, steel chips are formed as waste material. The best way to reduce environmental pollution and improve waste recycling is to partially replace concrete with steel chips. Due to these factors and the abundance of material, steel chips were used as a partial cement replacement at 0.5%, 1%, 1.5%, and 2% by the volume of cement. The properties such as compressive strength, split tensile strength, flexural beam strength, and modulus of elasticity are checked after 7, 14, and 28 days. Comparing these qualities to those of control molds showed that by raising the percentage of steel chips in the concrete up to 1.5%, mechanical characteristics are improved; however, when the percentage is increased to 2%, mechanical properties are also affected

Tuning the Photoresponse of Nano-Heterojunction: Pressure-Induced Inverse Photoconductance in Functionalized WO3 Nanocuboids

S.R. and S.S. contributed equally to this work. This work was mainly supported by the Natural Science Foundation of China (Grant No. 11874076), National Science Associated Funding (NSAF, Grant No. U1530402), and Science Challenging Program (Grant No. TZ2016001). D.E. thanks the financial support from Spanish MINECO under Grant No. MAT2016-75586-C4-1-P and from Generalitat Valenciana under Grant Prometeo/2018/123, EFIMAT. The X-ray diffraction measurements were performed at the BL15U1 station, Shanghai Synchrotron Radiation Facility (SSRF) in China. The HP XAS measurements were performed at 20 ID-C, APS, ANL. APS is supported by DOE-BES, under contract no. DE-AC02-06CH11357. The authors gratefully acknowledge Professor T. Irifune for providing the nanodiamonds for the HP XAS measurements, and K. Yang (SSRF), A. G. Li (SSRF), and C. J. Sun (APS) for their support in the in situ HP measurements.Inverse photoconductivity (IPC) is a unique photoresponse behavior that exists in few photoconductors in which electrical conductivity decreases with irradiation, and has great potential applications in the development of photonic devices and nonvolatile memories with low power consumption. However, it is still challenging to design and achieve IPC in most materials of interest. In this study, pressure-driven photoconductivity is investigated in n-type WO3 nanocuboids functionalized with p-type CuO nanoparticles under visible illumination and an interesting pressure-induced IPC accompanying a structural phase transition is found. Native and structural distortion induced oxygen vacancies assist the charge carrier trapping and favor the persistent positive photoconductivity beyond 6.4 GPa. The change in photoconductivity is mainly related to a phase transition and the associated changes in the bandgap, the trapping of charge carriers, the WO6 octahedral distortion, and the electron–hole pair recombination process. A unique reversible transition from positive to inverse photoconductivity is observed during compression and decompression. The origin of the IPC is intimately connected to the depletion of the conduction channels by electron trapping and the chromic property of WO3. This synergistic rationale may afford a simple and powerful method to improve the optomechanical performance of any hybrid material.Natural Science Foundation of China (Grant No. 11874076); National Science Associated Funding (NSAF, Grant No. U1530402); Science Challenging Program (Grant No. TZ2016001); Spanish MINECO MAT2016-75586-C4-1-P; Generalitat Valenciana under Grant Prometeo/2018/123, EFIMAT; Institute of Solid State Physics, University of Latvia as the Center of Excellence has received funding from the European Union’s Horizon 2020 Framework Programme H2020-WIDESPREAD-01-2016-2017-TeamingPhase2 under grant agreement No. 739508, project CAMART

Relationship of Anthropometric Indicators of General and Abdominal Obesity with Hypertension and Their Predictive Performance among Albanians: A Nationwide Cross-Sectional Study

Anthropometric indicators of general and abdominal obesity can predict cardiovascular disease outcomes. Their performance in predicting hypertension (HTN) varies across populations. We aimed to analyze the relationship of body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and conicity index (CI) with HTN, to examine their predictive performance and to determine their optimal cut-offs in a nationally representative sample of Albanians aged 15–59 years (n = 20,635). Logistic regression models were fitted and sex-specific receiver-operating characteristic (ROC) curves were constructed. The indicators were positively associated with HTN. Sex modified the relationships, as associations appeared significantly stronger among females than males in the highest categories of the indicators. The area under ROC curves (AUCs) for BMI were 0.729 (95% confidence interval (CI): 0.720–0.738) among females and 0.648 (95% CI: 0.633–0.663) among males, and AUCs for WHtR were 0.725 (95% CI: 0.716–0.734) among females and 0.637 (95% CI: 0.622–0.652) among males. However, the AUCs for BMI and WHtR did not differ significantly among females (p = 0.279) and males (p = 0.227). BMI outperformed WC and CI in both sexes. The optimal BMI cut-offs were 27.0 kg/m2 among females and 25.6 kg/m2 among males, and that for WHtR were 0.53 among females and 0.54 among males. BMI and WHtR demonstrated similar discriminatory power, and the identified cut-offs may inform initiatives for structured HTN screening in Albania

Factors Affecting Investigative Journalism in Pakistan: Exploring Journalists’ Perceptions

Investigative journalism is an important part of journalism practices as it unveils the matters that are deliberately hidden from society. This study aims to examine how journalists perceive the factors affecting investigative journalism in Pakistan. More specifically, how intra, extra, and within-media elements influence media content and decisions of coverage. Through purposive sampling method and for data collection procedure, structured questionnaire tool was utilized. The results showed that certain forces inside and outside the media organizations impact media content in Pakistan. These influences include organizational sources, pressure groups, personal biases, job threats, economic constraints. Thus the study proposes that journalism in Pakistan can meet its true objectives only by dealing or at least minimizing the factors affecting investigative journalism in Pakistan.&nbsp

Making semaglutide accessible in Pakistan: A crucial step for heart failure treatment

Madam, In 2019, the FDA approved a new Semaglutide pill to help adults with type 2 diabetes control their blood sugar.1 This medication works because it mimics a natural hormone called glucagon-like peptide-1 (GLP-1).1,2 Originally, it was considered an add-on treatment for people who already take other medications.1 But in January 2023, the FDA updated the approval so that Semaglutide can be used as the first medication for some adults with type 2 diabetes, along with healthy lifestyle changes.1 Recently,a SELECT trial was conducted, which shows its renoprotective function.4 Beyond these uses, research exposes the potential of semaglutide to dramatically improve heart health, even slashing the risk of death and heart failure.1,2,4 Although this holds an importance for heart failure patients, the greater importance of it comes from the fact that it has shown beneficial results in heart failure with preserved ejection fraction patients too, which is a type of heart failure that’s predominant among diabetic and obese individuals.3 This makes it a drug of interest in cardiology as we have only a limited number of drugs to treat the hopeful population. This letter examines the expanded role of Semaglutide, encompassing its existing uses and emerging application in hfpEF treatment. A new study by Michael et al., published in The New England Journal of Medicine in April 2024, investigated the use of Semaglutide for obese patients with heart failure with preserved ejection fraction (HfpEF) and type 2 diabetes (DM2). This double-blind, randomized, multinational trial enrolled 616 participants from 16 countries and compared Semaglutide treatment (STEP-HfpEF DM trial) to a placebo control group.The study included adults aged 18 and over with a body mass index (BMI) of 30 or greater who had been diagnosed with both HfpEF and DM2. Half the participants received once-weekly Semaglutide injections for a year, while the others received a placebo. Compared to the placebo group, those taking Semaglutide for the next 52 weeks showed significant improvements in heart failure symptoms and physical limitations (13.7 point increase vs. 6.4 point increase). Additionally, the Semaglutide group experienced a substantial weight loss (9.8% reduction) and a greater improvement in their six-minute walk test distance (12.7 meters on average).2 However,17.7% of participants reported side effects such as gastrointestinal disorders and infections.However, the overall findings suggest this drug may significantly improve heart failure symptoms, physical function, and weight loss in obese patients with HfpEF and DM2, with acceptable side effects.2,5 ---Continu