An Introduction to Patchouli (Pogostemon cablin Benth.) – A Medicinal and Aromatic Plant: It’s Importance to Mankind

Patchouli (Pogostemon cablin Benth.) is a plant from Lamiaceae family, well known for its medicinal and aromatic properties.  Patchouli is grown for its essential oil.  Patchouli essential oil is mainly obtained by steam distillation of the shade dried leaves.  It is widely appreciated for its characteristic pleasant and long lasting woody, earthy, camphoraceous odour.  It is especially notable as the essential oil extracted is internationally important and valuable, principally for the aromatherapy, perfumery, cosmetics, incense stick production and food flavouring industries.  This review attempted to give an overview of the relationship between aromatherapy and essential oils, importance of patchouli, harvesting pattern of patchouli, basics behind drying and steam distillation of patchouli crop, as well as trends existing in the various markets for essential oil application and its importance to mankind.   Keywords: patchouli, aromatherapy, drying, steam distillation, essential oil, application

Vascular compliance in lean, obese, and diabetic children and adolescents: a cross-sectional study in a minority population.

BACKGROUND: In adults, both obesity and type 2 diabetes mellitus (T2DM) are positively correlated with cardiovascular disease mortality and arterial stiffness. Several studies of adults have shown that both obesity and T2DM are independently associated with increased arterial stiffness. However, little is known about the relationship between arterial compliance and cardiovascular disease risk in children. We assessed whether large and small arterial compliance is impaired in obese and diabetic pubertal children. METHODS: One hundred children of African-Caribbean ethnicity, aged 14-16 years, including 21 lean children (between the 25th and 75th percentile), 40 obese children (\u3e95th percentile), and 39 children with T2DM diagnosed by American Diabetes Association criteria were studied. Arterial compliance of the large (C1) and small (C2) vessels was measured using radial arterial diastolic pulse wave contour analysis. RESULTS: C1 did not differ significantly between lean, obese, and T2DM subjects. C2 was significantly greater in obese and T2DM subjects (10.9 ± 1 and 10.4 ± 0.7 ml/mm Hg × 100 ml, respectively) compared to lean subjects (7.8 ± 0.8 ml/mm Hg × 100 ml; p \u3c 0.05). C2 was also significantly greater in T2DM subjects receiving antihypertensive drug therapy than in diabetic subjects not on antihypertensive treatment. CONCLUSION: Increased compliance in diabetic and obese children compared to lean subjects could be secondary to premature maturation of the vascular system; whether this early maturation can translate into a subsequent rise in the incidence of cardiovascular events related to diabetes and obesity can only be determined by long-term follow-up of these patients

Ambulatory Blood Pressure Monitoring in Lean, Obese and Diabetic Children and Adolescents.

AIM: To determine if children and adolescents who have obesity (Ob) or type 2 diabetes (T2DM) of relatively short duration have impaired cardiovascular function compared with lean subjects using 24-hour ambulatory blood pressure as a surrogate measure of evaluation. METHODS: We enrolled 100 African-Caribbean subjects (45 males/55 females), mean ages 14.4-15.2 years (range 11.8-18.5 years) and Tanner stage 4.2-4.8. Mean BMI for the Ob (n = 40), T2DM (n = 39) and lean (n = 21) groups were 40.3, 34.2 and 20.8, respectively (p \u3c 0.01, Ob and T2DM vs. lean). Mean hemoglobin A1c in lean and Ob was 5.4 and 5.5% compared to 8.8% in T2DM (p \u3c 0.001, T2DM vs. lean and Ob). Ambulatory blood pressure was recorded every 20 min over 24 h using Spacelabs 70207. RESULTS: Mean 24-hour, daytime and nighttime systolic blood pressure was significantly higher in Ob and T2DM compared with lean subjects (mean 24-hour 117 and 120 vs. 109 mm Hg; daytime 121 and 123 vs. 113 mm Hg; and nighttime 109 and 115 vs. 101 mm Hg; p \u3c 0.01 for all time periods). The nocturnal systolic dip in Ob and T2DM did not differ from that of lean, whereas nocturnal diastolic dip decreased significantly in Ob and T2DM compared to lean (11.5 and 10.4 vs. 20.6 mm Hg; p \u3c 0.01). Mean pulse pressure was significantly increased in the Ob and T2DM groups compared to lean subjects (51 and 54 vs. 45 mm Hg; p \u3c 0.01). CONCLUSION: Adolescent Ob and T2DM groups share adverse risk factors, which may be harbingers of adult cardiovascular events