What We Know About the Genetic Determinants of Human Homosexuality? A Short Review Communication

“Homosexualism”, “sexual orientation disorder”, “egodistonic homosexuality”, “unspecified sexual disorder”, “sexual maturity disorder” and “sexual relationship disorder”. Since 1948, these have been, throughout the history of the Diagnostic and Statistical Manual of Mental Disorders (DCM) and the International Statistical Classification of Diseases and Related Health Problems (ICD), the terms used by the scientific community to categorize the homoaffective spectrum until in 2017, in the face of strong social and academic demand, their complete disengagement from any terminology that categorizes them as physical and/or mental illness. On the other hand, some areas of science have contributed substantially to a better understanding of this subject, such as genetics and epigenetics. Today, although the scientific community still offers some points of resistance, especially in more conservative countries, it is a consensus that since the implementation of the genome project there has been a considerable methodological expansion that has opened new possibilities of studies that have allowed this advance

Energy metabolism: gluconeogenesis and oxidative phosphorylation

Most animal cells are able to meet their energy needs from the oxidation of various types of compounds: sugars, fatty acids, amino acids, but some tissues and cells of our body depend exclusively on glucose and the brain is the largest consumer of all. That is why the body has mechanisms in order to keep glucose levels stable. As it decreases, the degradation of hepatic glycogen occurs, which maintains the appropriate levels of blood glucose allowing its capture continues by those tissues, even in times of absence of food intake. But this reserve is limited, so another metabolic pathway is triggered for glucose production, which occurs in the kidneys and liver and is called gluconeogenesis, which means the synthesis of glucose from non-glucose compounds such as amino acids, lactate, and glycerol. Most stages of glycolysis use the same enzymes as glycolysis, but it makes the opposite sense and differs in three stages or also called deviations: the first is the conversion of pyruvate to oxaloacetate and oxaloacetate to phosphoenolpyruvate. The second deviation is the conversion of fructose 1,6 biphosphate to fructose 6 phosphate and the third and last deviation is the conversion of glucose 6 phosphate to glucose

Transversal Diagnosis of the Panorama of Professional Education: A Case Study of the City of Itaporã – Mato Grosso do Sul

This case study aims to identify the demand for professional education courses in the city of Itaporã, in the state of Mato Grosso do Sul, in the year 2020, offering a cross-cutting diagnosis of this educational panorama; for this purpose, the technique of guided interview in loco was implemented with the action coordinating agents designated by the municipal administration. All those involved were aware of their free and voluntary collaboration. During the entire collection phase, the information was recorded through a free association chart which, later revised, gave basis to the identification that in the disclosure phase there is no time to contact the possible students taking into account that, besides the districts, the municipality aggregates a vast rural region. In addition, the fact that the course is offered only at night, ends up discouraging the participation of some potential students who, despite showing interest, need to pay attention to their labor routines. It is concluded that a greater concern is needed to create a database of course graduates in order to establish a periodic sense capable of identifying professional life after the course, in addition to profiling the demand for skilled labor in order to detect which training is important at the moment

Discourse Analysis On Physical Activity For People With Disabilities

The subject discussed refers to the importance of physical activity for people with disabilities, both in physical and psychological aspects. The general objective of this work is to identify the relationship of the person with disability to the sport, as guaranteed by the Federal Constitution, giving the person with disability the right to the sport. As a specific objective, to analyze through journalistic texts what is the perception of the person with disability in face of his/her limitations. The methodology used will be an analytical approach, together with bibliographic and documentary research. The relevance for the study of this theme is the look at the person with disability, which is often forgotten by the public power, or pre-judged by the society that most of the times does not know the concept of disability, or when they come across it, they do not know how to act or how to treat a person with disability. Maybe because they don't even know how they think according to their current life condition, as to the difficulties, as to the accessibility, as to the expectations, as to the way they are seen or treated by society. This raises a question: How are people with disabilities treated by society and public authorities? Are their rights being respected? This answer can be traced back to a critical analysis of a person with disability's discourse