9 research outputs found

    Detection and elimination of cellular bottlenecks in protein-producing yeasts

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    Yeasts are efficient cell factories and are commonly used for the production of recombinant proteins for biopharmaceutical and industrial purposes. For such products high levels of correctly folded proteins are needed, which sometimes requires improvement and engineering of the expression system. The article summarizes major breakthroughs that led to the efficient use of yeasts as production platforms and reviews bottlenecks occurring during protein production. Special focus is given to the metabolic impact of protein production. Furthermore, strategies that were shown to enhance secretion of recombinant proteins in different yeast species are presented

    A review of the mechanical and thermal properties of graphene and its hybrid polymer nanocomposites for structural applications

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    Carbon nanotube- and graphene-reinforced multiphase polymeric composites: review on their properties and applications

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