7,757 research outputs found
Closed Strings in Misner Space: Stringy Fuzziness with a Twist
Misner space, also known as the Lorentzian orbifold , is the
simplest tree-level solution of string theory with a cosmological singularity.
We compute tree-level scattering amplitudes involving twisted states, using
operator and current algebra techniques. We find that, due to zero-point
quantum fluctuations of the excited modes, twisted strings with a large winding
number are fuzzy on a scale , which can be much larger than
the string scale. Wave functions are smeared by an operator reminiscent of the Moyal-product of non-commutative
geometry, which, since is real, modulates the amplitude rather
than the phase of the wave function, and is purely gravitational in its origin.
We compute the scattering amplitude of two twisted states and one tachyon or
graviton, and find a finite result. The scattering amplitude of two twisted and
two untwisted states is found to diverge, due to the propagation of
intermediate winding strings with vanishing boost momentum. The scattering
amplitude of three twisted fields is computed by analytic continuation from
three-point amplitudes of states with non-zero in the Nappi-Witten plane
wave, and the non-locality of the three-point vertex is found to diverge for
certain kinematical configurations. Our results for the three-point amplitudes
allow in principle to compute, to leading order, the back-reaction on the
metric due to a condensation of coherent winding strings.Comment: 29 pages, Latex2e, uses JHEP3.cls; v3: minor corrections, final
version to appear in JCA
Lyman alpha SMM/UVSP absolute calibration and geocoronal correction
Lyman alpha observations from the Ultraviolet Spectrometer Polarimeter (UVSP) instrument of the Solar Maximum Mission (SMM) spacecraft were analyzed and provide instrumental calibration details. Specific values of the instrument quantum efficiency, Lyman alpha absolute intensity, and correction for geocoronal absorption are presented
Stavroginâs Crime and Punishment Revisited: Dostoevskian Intertexts in J.M. Coetzeeâs Disgrace (1999)
F.M. Dostoevsky has often been acknowledged as one of the major influences on contemporary South African-born novelist J.M. Coetzee. Nevertheless, his 1999 Booker Prize-winning Disgrace has not been given a reading in consistently Dostoevskian terms. Therefore, the present paper focuses on the implicit intertextual links connecting Disgrace to Devils (1872) and Crime and Punishment (1866). I will argue that Coetzeeâs central character, David Lurie is a present-day rewriting of both Dostoevskian Stavrogin and Raskolnikov. As to the first of these, I read Lurieâs engagement with the Romantic figure of Byron as a critique of the Romantic aspects of Stavroginâs character in Devils. Second, I will argue that while Lurie and his crime largely evoke Stavrogin, his fate is also a âcorrectiveâ rewriting of Raskolnikovâs: apart from the obvious thematic similarities, Coetzeeâs novel is also clearly reminiscent of both Dostoevskian charactersâ respective narratives in its central scenes of confession. Coetzee, however, seems to most ambiguously revise the Dostoevskian motif of ârewardingâ both Raskolnikov and Stavrogin with epiphanic visions, just like Stavroginâs potential liberation from guilt in suicide. Lurie has to live on with the consequences of crimes committed and suffered, turning for most equivocal relief to Romantic art again in the closing scenes of the novel. All in all, the exploration of both intertextual references contributes to an understanding of Disgrace as an ambiguous comment on depriving evil of its Romantic aspects in a continuing polemic with Dostoevsky
Progression of myopathology in Kearns-Sayre syndrome
We report on the progression of myopathology by comparing two biopsies from a patient with a Kearns-Sayre-Syndrome. The first biopsy was taken in 1979 and showed 10% ragged-red fibers. Myopathic changes were slight including internal nuclei and fiber splitting in 10% of the fibers. Electron microscopy revealed typical mitochondrial abnormalities with regard to number and shape. In 1989 a second biopsy was performed for an extended analysis of mitochondrial DNA. This time less than 5% of all fibers were ragged-red. Severe myopathic changes could be detected which so far has rarely been reported in mitochondrial cytopathy
Benutzerforschung fĂŒr zwei Teilbibliotheken der UniversitĂ€tsbibliothek Graz
User studies for two branch libraries of the Graz University Library (translation of the title). In this paper a user study for two libraries of the University of Graz, namely the main library and the Law and Social and Economic Sciences Library, is presented. In detail, user structure, user behavior, and user satisfaction are evaluated by interviewing 276 library users. The results reveal that most users are students who use both libraries quite intensively and are quite satisfied with the existing offer
Interaction and localisation studies of the lipoteichoic acid synthesis proteins in staphylococcus aureus
Lipoteichoic acid (LTA) is an important component of the cell envelope of various Gram-positive
bacteria. In Staphylococcus aureus it consists of a polyglycerolphosphate chain that is decorated
with D-alanine esters and anchored to the cell membrane via a glycolipid. The lack of D-alanine
modifications leads to increased susceptibility to cationic antimicrobial peptides and the complete
absence of LTA results in aberrant positioning of septa, enlargement of cells and eventual cell
lysis, indicating a link between LTA synthesis and cell division. Although key enzymes required for
LTA synthesis and D-alanylation have been identified, the full process has not been elucidated and
is investigated in this study.
Using a bacterial two-hybrid approach it was shown that the three key LTA synthesis enzymes, YpfP,
LtaA and LtaS, interact with one another, indicating the formation of a multi-enzyme complex. In
addition, these three proteins interacted with numerous cell division and peptidoglycan synthesis
proteins. Fluorescence microscopy studies indicated that YpfP and LtaA localise to the membrane,
while LtaS appeared to accumulate at the site of cell division in cells with fully formed septa.
Together, these data provide further experimental evidence for the coordination between the
processes of cell division and LTA synthesis.
Four proteins, DltA-D, are essential for the D-alanylation of LTA. The mechanism begins with DltA
transferring D-alanines onto the carrier protein DltC. However, Fischer and colleagues, and Neuhaus
and Baddiley have proposed two conflicting models for the remainder of the mechanism for
D-alanylation. Here, using a cellular protein localisation analysis it was shown that DltC does not
traverse the membrane and membrane topology studies indicated that DltD is anchored to the outside
of the cell, contrary to the Neuhaus and Baddiley model. In summary, the data presented in this
study are in support of the D-alanine substitution model proposed by
Werner Fischer.Open acces
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