9,595 research outputs found
Gravitons and Lightcone Fluctuations II: Correlation Functions
A model of a fluctuating lightcone due to a bath of gravitons is further
investigated. The flight times of photons between a source and a detector may
be either longer or shorter than the light propagation time in the background
classical spacetime, and will form a Gaussian distribution centered around the
classical flight time. However, a pair of photons emitted in rapid succession
will tend to have correlated flight times. We derive and discuss a correlation
function which describes this effect. This enables us to understand more fully
the operational significance of a fluctuating lightcone. Our results may be
combined with observational data on pulsar timing to place some constraints on
the quantum state of cosmological gravitons.Comment: 16 pages and two figures, uses eps
The exact three-dimensional half-shell t-matrix for a sharply cut-off Coulomb potential in the screening limit
The three-dimensional half-shell t-matrix for a sharply cut-off Coulomb
potential is analytically derived together with its asymptotic form without
reference to partial wave expansion. The numerical solutions of the
three-dimensional Lippmann-Schwinger equation for increasing cut-off radii
provide half-shell t-matrices which are in quite a good agreement with the
asymptotic values.Comment: 15 pages, 4 eps figure
Validity of estimating center of pressure during walking and running with plantar load from a three-sensor wireless insole
NICE guidance on long-term sickness and incapacity
Long-term sickness absence and incapacity benefits (disability pension) rates have increased across industrialised countries. Effective measures are needed to support return to work. The recommendations of this guidance were informed by the most appropriate available evidence of effectiveness and cost-effectiveness. Public health evidence was provided by research using a variety of study designs that attempted to determine the outcome of a particular intervention by evaluating status before and after the intervention had been effected, and was not limited to randomised control trials. Where the evidence base was depleted or underdeveloped, expert witnesses were called to give their opinion on the best available evidence and emerging interventions. The process enabled challenge and contestability from stakeholder groups at different points as the guidance was developed. Forty-five heterogeneous studies were included in the review of interventions to reduce long-term sickness absence and transitions from short-term to long-term absence (mainly covering the former and also mainly examining musculoskeletal conditions). The analysis of evidence was restricted to descriptive synthesis. Three general themes emerged from an analysis of the studies that were more likely to report positive results: early interventions; multidisciplinary approaches; and interventions with a workplace component. Two further reviews were undertaken, one on interventions to reduce the re-occurrence of sickness absence, which identified seven studies on lower back pain, and concluded that early intervention and direct workplace input are important factors. The final evidence review focused on six studies of interventions for those in receipt of incapacity benefit. The evidence was that work-focused interviews coupled with access to tailored support are effective and cost-effective interventions. Practitioners should consider the impact of interventions and management options on work ability for patients of working age. Work ability should be considered a key outcome for future intervention studies
Radiation from the non-extremal fuzzball
The fuzzball proposal says that the information of the black hole state is
distributed throughout the interior of the horizon in a `quantum fuzz'. There
are special microstates where in the dual CFT we have `many excitations in the
same state'; these are described by regular classical geometries without
horizons. Jejjala et.al constructed non-extremal regular geometries of this
type. Cardoso et. al then found that these geometries had a classical
instability. In this paper we show that the energy radiated through the
unstable modes is exactly the Hawking radiation for these microstates. We do
this by (i) starting with the semiclassical Hawking radiation rate (ii) using
it to find the emission vertex in the CFT (iii) replacing the Boltzman
distributions of the generic CFT state with the ones describing the microstate
of interest (iv) observing that the emission now reproduces the classical
instability. Because the CFT has `many excitations in the same state' we get
the physics of a Bose-Einstein condensate rather than a thermal gas, and the
usually slow Hawking emission increases, by Bose enhancement, to a classically
radiated field. This system therefore provides a complete gravity description
of information-carrying radiation from a special microstate of the nonextremal
hole.Comment: corrected typo
On Infrared Effects in de~Sitter Background
We have estimated higher order quantum gravity corrections to de~Sitter
spacetime. Our results suggest that, while the classical spacetime metric may
be distorted by the graviton self-interactions, the corrections are relatively
weaker than previously thought, possibly growing like a power rather than
exponentially in time.Comment: 17, UM-TH-94-11, (1 postscript fig. at end
Constituting monetary conservatives via the 'savings habit': New Labour and the British housing market bubble
The ongoing world credit crunch might well kill off the most recent bubble dynamics in the British housing market by driving prices systematically downwards from their 2007 peak. Nonetheless, the experience of that bubble still warrants analytical attention. The Labour Government might not have been responsible for consciously creating it, but it has certainly grasped the opportunities the bubble has provided in an attempt to enforce a process of agential change at the heart of the British economy. The key issue in this respect is the way in which the Government has challenged the legitimacy of passive welfare receipts in favour of establishing a welfare system based on incorporating the individual into an active asset-holding society. The housing market has taken on new political significance as a means for individuals first to acquire assets and then to accumulate wealth on the back of asset ownership. The ensuing integration of the housing market into an increasingly reconfigured welfare system has permeated into the politics of everyday life. It has been consistent with individuals remaking their political subjectivities in line with preferences for the type of conservative monetary policies that typically keep house price bubbles inflated
The GALFA-HI Compact Cloud Catalog
We present a catalog of 1964 isolated, compact neutral hydrogen clouds from
the Galactic Arecibo L-Band Feed Array Survey Data Release One (GALFA-HI DR1).
The clouds were identified by a custom machine-vision algorithm utilizing
Difference of Gaussian kernels to search for clouds smaller than 20'. The
clouds have velocities typically between |VLSR| = 20-400 km/s, linewidths of
2.5-35 km/s, and column densities ranging from 1 - 35 x 10^18 cm^-2. The
distances to the clouds in this catalog may cover several orders of magnitude,
so the masses may range from less than a Solar mass for clouds within the
Galactic disc, to greater than 10^4 Solar Masses for HVCs at the tip of the
Magellanic Stream. To search for trends, we separate the catalog into five
populations based on position, velocity, and linewidth: high velocity clouds
(HVCs); galaxy candidates; cold low velocity clouds (LVCs); warm, low
positive-velocity clouds in the third Galactic Quadrant; and the remaining warm
LVCs. The observed HVCs are found to be associated with previously-identified
HVC complexes. We do not observe a large population of isolated clouds at high
velocities as some models predict. We see evidence for distinct histories at
low velocities in detecting populations of clouds corotating with the Galactic
disc and a set of clouds that is not corotating.Comment: 34 Pages, 9 Figures, published in ApJ (2012, ApJ, 758, 44), this
version has the corrected fluxes and corresponding flux histogram and masse
The Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans: The Jackson Heart Study
OBJECTIVE We assessed the relation of diabetes and insulin resistance (IR) on left ventricular (LV) structure and function in African Americans.
RESEARCH DESIGN AND METHODS Among those receiving echocardiograms in cycle 1 of the Jackson Heart Study, we assessed the sex-specific relation of fasting blood glucose (FBG), diabetes, and IR to LV structure and function, adjusting for age, systolic blood pressure, antihypertensive medications, and BMI.
RESULTS Among 2,399 participants, LV mass index (Pwomen = 0.0002 and Pmen = 0.02), posterior wall thickness (Pwomen = 0.01 and Pmen = 0.05), and interventricular septal wall thickness (Pwomen = 0.01) were related to FBG categories. Among those with normal FBG and no diabetes, concentric remodeling and low ejection fraction in women and LV mass index and posterior wall thickness in men were related to IR.
CONCLUSIONS In the largest study of its kind in a community-based cohort of African Americans, we found a relation of FBG category and IR to LV structure and function
Two alternative methods for the retrieval of somatic cell populations from the mouse ovary
Many modern techniques employed to uncover the molecular fundamentals underlying biological processes require dissociated cells as their starting point/substrate. Investigations into ovarian endocrinology or folliculogenesis therefore necessitate robust protocols for dissociating the ovary into its constituent cell populations. While in the mouse, methods to obtain individual, mature follicles are well-established, the separation and isolation of single cells of all types from early mouse follicles, including somatic cells, has been more challenging. Herein we present two methods for the isolation of somatic cells in the ovary. These methods are suitable for a range of applications relating to the study of folliculogenesis and mouse ovarian development. First, an enzymatic dissociation utilising collagenase and a temporary, primary cell culture step using neonatal mouse ovaries which yields large quantities of granulosa cells from primordial, activating, and primary follicles. Second, a rapid papain dissociation resulting in a high viability single cell suspension of ovarian somatic cells in less than an hour, which can be applied from embryonic to adult ovarian samples. Collectively these protocols can be applied to a broad array of investigations with unique advantages and benefits pertaining to both
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