Water ice clouds in a martian global climate model using data assimilation

The water cycle is one of the key seasonal cycles on Mars, and the radiative effects of water ice clouds have recently been shown to alter the thermal structure of the atmosphere. Current Mars General Circulation Models (MGCMs) are capable of representing the formation and evolution of water ice clouds, though there are still many unanswered questions regarding their effect on the water cycle, the local atmosphere and the global circulation. We discuss the properties of clouds in the LMD/UK MGCM and compare them with observations, focusing on the differences between the water ice clouds in a standalone model and those in a model which has been modified by assimilation of thermal and aerosol opacity spacecraft data

Midwinter suppression of baroclinic storm activity on Mars: observations and models

We present results from assimilated analyses of observations from the Mars Global Surveyor Thermal Emission Spectrometer showing evidence for a regular suppression of baroclinic circumpolar storm activity in both hemispheres of Mars around winter solstice. General circulation model simulations are then used to elucidate the structure and possible causes of this suppression, for which the local ‘Eady growth rate’ appears to be a good predictor

Dust-related interannual and intraseasonal variability of Martian climate using data assimilation

Data assimilation has been applied in several studies [Montabone et al., 2005; Lewis et al., 2005; Montabone et al., 2006a; Montabone et al., 2006b; Lewis et al., 2007; Wilson et al., 2008; Rogberg et al. 2010] as an effective tool with which to analyze spacecraft observations and phenomena (e.g., atmospheric tides, transient wave behavior, effects of clouds in the tropics, weather predictability, etc.) in the Martian atmosphere. A data assimilation scheme combined with a Martian Global Circulation Model (GCM) is able to provide a complete, balanced, four-dimensional solution consistent with observations. The GCM we use [Forget et al., 1999] combines a spectral dynamical solver and a tracer transport scheme developed in UK and Laboratoire de Météorologie Dynamique (LMD; Paris, France) physics package developed in collaboration with Oxford, The Open University and Instituto de Astrofisica de Andalucia (Granada, Spain). Here, we describe and discuss dust-related interannual and intraseasonal variability of the Martian climate. The results shown in this study come from a reanalysis using the Martian GCM with data assimilation scheme which assimilates Mars Global Surveyor/ Thermal Emission Spectrometer (MGS/TES) retrievals of temperature and column dust opacity. The detailed model setup was described by Montabone et al. [2006a], and the data assimilation scheme employed in this study was introduced in the work of Lewis et al. [2007]

Midwinter suppression of baroclinic storm activity on Mars: observations and models

Baroclinic instability and intense traveling wave activity on Mars is well known to occur in “storm zones” (Hollingsworth et al. 1996) close to the edge of the advancing or retreating polar ice cap. Such activity usually sets in during Martian fall and continues until the onset of the summer season when large-scale instability mostly ceases as the atmosphere is no longer baroclinically unstable. The stormy season is typically characterized by large-scale, zonally-propagating waves with zonal wavenumbers m = 1-3, the lower wavenumber modes typically penetrating to considerable altitude though may also be surface-intensified. As we show below, however, some observations suggest that this eddy activity does not persist uniformly throughout the autumn, winter and spring seasons, but appears to die down quite consistently within 10 sols or so either side of the winter solstice. This midwinter ‘solsticial pause’ appears to be a sufficiently consistent feature of each winter season in both hemispheres to be regarded as a significant feature of Martian climatology, and could affect a variety of aspects of Martian meteorology including global heat and momentum transport, occurrence of dust storms etc. A somewhat similar phenomenon has also been documented for the Earth (e.g. Nakamura 1992; Penny et al. 2010), especially in relation to seasonal variations in the north Pacific storm tracks. The cause of this phenomenon is still not well established, though suggested mechanisms include the effects of enhanced barotropic shear (the so-called ‘barotropic governor’ (James & Gray 1986) and interactions with topography over central Asia. In this presentation we examine evidence for this phenomenon in the assimilated record of Martian climate from the Thermal Emission Spectrometer on board the Mars Global Surveyor mission (MGSTES), in conjunction with the UK version of the LMD-Oxford-OU-IAA Mars GCM (Forget et al. 1999; Montabone et al. 2006; Lewis et al. 2007). This is further corroborated in other evidence from seasonal variations in the incidence of local and regional dust storms that owe their origin to circumpolar baroclinic storms. We also discuss the extent to which this ‘solsticial pause’ phenomenon is reproduced in stand-alone atmospheric models and present results of some simulations to test a number of hypotheses for its dynamical origin on Mars

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia.

We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing, serotyping, and reverse transcription qPCR. Five lung aspirates cultured pneumococci, with a matching strain identified in the nasopharynx. Three virulence genes including ply (pneumolysin) were upregulated >20-fold in the lung compared with the nasopharynx. Nasopharyngeal pneumococcal density was higher in pediatric pneumonia patients compared with controls (p <0.0001). Findings suggest that changes in pneumococcal gene expression occurring in the lung environment may be important in pathogenesis

In vitro and ex vivo evaluation of N‐methyl benzilates as potential PET agents for muscarinic receptors

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90199/1/25802601207_ftp.pd

Long Duration Exposure Facility (LDEF) attitude measurements of the Interplanetary Dust Experiment

Analysis of the data from the Long Duration Exposure Facility (LDEF) Interplanetary Dust Experiment (IDE) sun sensors has allowed a confirmation of the attitude of LDEF during its first year in orbit. Eight observations of the yaw angle at specific times were made and are tabulated in this paper. These values range from 4.3 to 12.4 deg with maximum uncertainty of plus or minus 2.0 deg and an average of 7.9 deg. No specific measurements of pitch or roll were made but the data indicates that LDEF had an average pitch down attitude of less than 0.7 deg