4 research outputs found
Early Diagnosis and Treatment of Ectopic Pregnancy
During the period from 1995 to 1999, 64 patients were treated for ectopic pregnancy.
All patients admitted to the department passed the same procedure including (complete
preoperative laboratory findings, Beta HCG, serum progesterone and transvaginal colour
Doppler). In patients who had ultrasound finding typical for ectopic pregnancy in
combination with positive Beta HCG, conservative treatment was primarily done. In the
rest of the patients, Beta HCG was tested every second day and in combination with the
clinical and vaginosonographical findings the patients underwent diagnostic or operative
laparoscopy. Out of 64 patients 36 had visible ectopic pregnancy when admitted to
the clinical department. Three patients had no visible ectopic pregnancy neither at the
time of their admission to the department nor at the time of laparoscopy. One of them
had cervical pregnancy and the other two had pregnancies in the uterine part of the
tube. The patient with cervical pregnancy was treated with metrotrexat (MTX) 12 mg
daily in 5 doses. One patient with cornual pregnancy was treated with high doses of
oxytocin infusion in combination with MEB intravenously 3x1 amp. The other patient
with cornual pregnancy underwent laparoscopy with cornual resection and salpingectomy.
Four of other tubar pregnancies were treated with metrotrexat 12mg/day for 5
days. Other ectopic pregnancies were treated as follows: 36 laparoscopic salpingectomies,
10 laparoscopic salpingotomies with ovum expression, 9 adnexectomies by laparotomy,
and 2 laparoscopic adnexectomies
Histoenzymatic and Immunocytochemical Characteristics of Extravillous Trophoblast Cells of Placental Basal Plate as Parameter of Their Function in Hypertensive Pregnancy
An intense activity of enzymes which actively participate in the renin-angiotensinaldosterone
system was shown in extravillous trophoblast cells which are involved in
the performing of spiral arteries into uteroplacental vessels. The hydrolase activity in
villous trophoblast underwent important variations, but it was constant in cells of the
extravillous trophoblast. Activity of lysosomal hydrolases, of leucine aminopeptidase
and N-acetyl glucosaminidase type, was markedly positive in X-cells, while negative in
the villous trophoblast. Beta glucuronidase activity has shown moderate activity in cells
of extravillous trophoblast, while in villous trophoblast it was weakly emphasized or
negative. Intense activity of prostaglandin E2 dehydrogenase in the way of strongly emphasized
microsomal reaction was noted exclusively in extravillous cells of basal plate,
especially in perivascular cell groupings. Within all examined enzymes activities, only
the membranous activity of alkaline phosphatase was of the same intensity in cells of
extravillous trophoblast. Lacking of penetration of these cells into the spiral arteries
wall in EPH-gestosis, which also means loss of their close contact with the blood of a
pregnant, implicates the practical meaning of these observations
Attitudes, Behaviour and Knowledge on Sexuality among Female Adolescents in Zagreb, Croatia
The aim of this study was to estimate the level of knowledge about sexuality, attitudes and sexual behaviour of female adolescents. The study included 194 female students, 117 from Medical High School (MHS) and 77 from General High School (GHS) in Zagreb. Data was collected using an anonymous self-administered questionnaire. In addition to items on personal data (age, parental education etc.), the participants were asked to define terms about sexuality (e.g. menstruation, puberty) the definitions of which are found in biology textbooks for the fifth and eighth grade of primary school. The aim of the third part of the survey was to collect information about attitudes and behaviour of female adolescents. The results showed a low level of knowledge in students of both schools. General High School students showed a higher level of knowledge than their Medical High School peers. One fifth of General High School students and 1/3 of Medical High School students were unable to define the term »menstruation«. The majority of adolescents talk about sexuality with their friends, 92.1% of General High School and 81.2% of Medical High School students. Almost 50% of students of both schools would like to talk about sexuality with their school doctor. 6.9% of Medical High School students had at least one sexual intercourse while none of the General High School students had been sexually active at the time of the survey. As the majority of students were not sexually active and results showed a rather low level of knowledge, this seems to be the ideal period for the implementation of educational programs aimed at increasing the level of knowledge, and thus preventing unwanted consequences (STD, pregnancy, abortion, infertility)