On unitarity of a linearized Yang-Mills formulation for massless and massive gravity with propagating torsion

A perturbative regime based on contortion as a dynamical variable and metric as a (classical) fixed background, is performed in the context of a pure Yang-Mills formulation for gravity in a $2+1$ dimensional space-time. In the massless case we show that the theory contains three degrees of freedom and only one is a non-unitary mode. Next, we introduce quadratical terms dependent on torsion, which preserve parity and general covariance. The linearized version reproduces an analogue Hilbert-Einstein-Fierz-Pauli unitary massive theory plus three massless modes, two of them represents non-unitary ones. Finally we confirm the existence of a family of unitary Yang-Mills-extended theories which are classically consistent with Einstein's solutions coming from non massive and topologically massive gravity. The unitarity of these YM-extended theories is shown in a perturbative regime. A possible way to perform a non-perturbative study is remarked.Comment: To appear in International Journal of Modern Physics

An in vitro evaluation of standard rotational thromboelastography in monitoring of effects of recombinant factor VIIa on coagulopathy induced by hydroxy ethyl starch

BACKGROUND: Rotational thromboelastography (ROTEG) has been proposed as a monitoring tool that can be used to monitor treatment of hemophilia with recombinant factor VIIa (rFVIIa). In these studies special non-standard reagents were used as activators of the coagulation. The aim of this study was to evaluate if standard ROTEG analysis could be used for monitoring of effects of recombinant factor VIIa (rFVIIa) on Hydroxy Ethyl Starch-induced dilutional coagulopathy. METHODS: The study was performed in vitro on healthy volunteers. Prothrombin time (PT) and ROTEG analysis were performed after dilution with 33% hydroxy ethyl starch and also after addition of rFVIIa to the diluted blood. RESULTS: PT was impaired with INR changing from 0.9 before dilution to 1.2 after dilution while addition of rFVIIa to diluted blood lead to an overcorrection of the PT to an International Normalized Ratio (INR) value of 0.6 (p = 0.01). ROTEG activated with the contact activator ellagic acid was impaired by hemodilution (p = 0.01) while addition of rFVIIa had no further effects. ROTEG activated with tissue factor (TF) was also impaired by hemodilution (p = 0.01) while addition of rFVIIa lead to further impairment of the coagulation (p = 0.01). CONCLUSIONS: The parameters affected in the ROTEG analysis were Clot Formation Time and Amplitude after 15 minutes while the Clotting Time was unaffected. We believe these effects to be due to methodological problems when using standard activators of the coagulation in the ROTEG analysis in combination with rFVIIa