898 research outputs found
Polymer Nanocomposite Materials Based on Carbon Nanotubes
(Invited Book Chapter
Scanning Tunneling Microscopy Studies of Chloroplasts in Solution
Previous work has shown that it is possible to image whole uncoated chloroplasts using scanning tunneling microscopy (STM), provided this is done in solution using tunnelling currents below about 100 pA.
More recent images include some which suggest that the STM is sensitive to dynamic processes occurring on chloroplast surfaces. Current-versus-distance curves and dI/ds measurements are consistent with tunnelling between the tip and sample surface, and relatively small deformations of the sample surface due to tip-sample forces. Attempts to use the same imaging conditions on bacteria were unsuccessful
Discovery of very nearby ultracool dwarfs from DENIS
We report new spectroscopic results, obtained with UKIRT/CGS4, of a sample of
14 candidate ultracool dwarfs selected from the DENIS (Deep Near-Infrared
Survey of the Southern Sky) database. A further object, selected from the 2MASS
Second Incremental Release, was observed at a later epoch with the same
instrument. Six objects are already known in the literature; we re-derive their
properties. A further four prove to be very nearby (~10 pc) mid-to-late
L-dwarfs, three unknown hitherto, two of which are almost certainly substellar.
These findings increase the number of L-dwarfs known within ~10 pc by ~25%. The
remainder of the objects discussed here are early L or very late M-type dwarfs
lying between ~45 and 15 pc and are also new to the literature. Spectral types
have been derived by direct comparison with J-,H- and K- band spectra of known
template ultracool dwarfs given by Leggett et al.
(ftp://ftp.jach.hawaii.edu/pub/ukirt/skl/dL.spectra/) For the known objects, we
generally find agreement to within ~1 subclass with previously derived spectral
types. Distances are determined from the most recent M_J vs. spectral type
calibrations, and together with our derived proper motions yield kinematics for
most targets consistent with that expected for the disk population; for three
probable late M-dwarfs, membership of a dynamically older population is
postulated. The very nearby L-type objects discussed here are of great interest
for future studies of binarity and parallaxes.Comment: 4 pages, 2 figures, accepted in A&A Letter
Southern Infrared Proper Motion Survey I: Discovery of New High Proper Motion Stars From First Full Hemisphere Scan
We present the first results from the Southern Infrared Proper Motion Survey.
Using 2 Micron All Sky Survey data along with that of the SuperCOSMOS sky
survey we have been able to produce the first widefield infrared proper motion
survey. Having targeted the survey to identify nearby M, L and T dwarfs we have
discovered 72 such new objects with proper motions greater than 0.5''/yr with
10 of these having proper motions in excess of 1''/yr. The most interesting of
these objects is SIPS1259-4336 a late M dwarf. We have calculated a
trigonometric parallax for this object of milliarcseconds
yielding a distance of pc. We have also discovered a common proper
motion triple system and an object with a common proper motion with LHS 128.
The survey completeness is limited by the small epoch differences between many
2MASS and UKI observations. Hence we only recover 22% of Luyten objects with
favourable photometry. However the Luyten study is itself unquantifiably
incomplete. We discuss the prospect of enhancing the survey volume by reducing
the lower proper motion limit.Comment: 20 pages, 11 figures, accepted for publication in Astronomy and
Astrophysic
325 MHz VLA Observations of Ultracool Dwarfs TVLM 513-46546 and 2MASS J0036+1821104
We present 325 MHz (90 cm wavelength) radio observations of ultracool dwarfs
TVLM 513-46546 and 2MASS J0036+1821104 using the Very Large Array (VLA) in June
2007. Ultracool dwarfs are expected to be undetectable at radio frequencies,
yet observations at 8.5 GHz (3.5 cm) and 4.9 GHz (6 cm) of have revealed
sources with > 100 {\mu}Jy quiescent radio flux and > 1 mJy pulses coincident
with stellar rotation. The anomalous emission is likely a combination of
gyrosynchrotron and cyclotron maser processes in a long-duration, large-scale
magnetic field. Since the characteristic frequency for each process scales
directly with the magnetic field magnitude, emission at lower frequencies may
be detectable from regions with weaker field strength. We detect no significant
radio emission at 325 MHz from TVLM 513-46546 or 2MASS J0036+1821104 over
multiple stellar rotations, establishing 2.5{\sigma} total flux limits of 795
{\mu}Jy and 942 {\mu}Jy respectively. Analysis of an archival VLA 1.4 GHz
observation of 2MASS J0036+1821104 from January 2005 also yields a
non-detection at the level of < 130 {\mu}Jy . The combined radio observation
history (0.3 GHz to 8.5 GHz) for these sources suggests a continuum emission
spectrum for ultracool dwarfs which is either flat or inverted below 2-3 GHz.
Further, if the cyclotron maser instability is responsible for the pulsed radio
emission observed on some ultracool dwarfs, our low-frequency non-detections
suggest that the active region responsible for the high-frequency bursts is
confined within 2 stellar radii and driven by electron beams with energies less
than 5 keV.Comment: 11 pages, 5 figures, submitted to A
Malondialdehyde Acetaldehyde Adducts (MAA-Adducts) Direct Distinctive Pro-Inflammatory Responses in Endothelial and Macrophage Cell Lines
Chronic inflammation plays a critical role in the pathogenesis of atherosclerosis. At present, the mechanism(s) by which inflammation contributes to this disease isnot entirely understood. Inflammation is known to induce oxidative stress, of which one consequence is lipid peroxidation. This process leads to the production of malondialdehyde (MDA), which can subsequently break down to form acetaldehyde (AA). These two aldehyde by-products can covalently interact with the ε-amino group of lysineswithin proteins and lipoproteins leading to the formation of highly immunogenic malondialdehyde-acetaldehyde adducts (MAA-adducts). The aim of this study was to determine the in-vitro cytokine response of endothelial cells and macrophages treated with MAA-modified human serum albumin (HSA-MAA) and low-density lipoprotein (LDL-MAA). In addition, cells isolated from mice with exposure to MAA and high fat diets were stained and imaged for uptake of the modified macromolecules of interest. We found that exposure of endothelial cells resulted in increased expression of IL-6, TNF-α, ICAM-1, VCAM-1, and MCP-1 in response to incubation with HSA-MAA; whereas, the same treatment of macrophages resulted in increased expression of IL-6, TNF-α, and IL-1b. LDL-MAA incubationresulted in increased TNF-α expression in macrophages, but MCP-1 was elevated in endothelial cells. Interestingly, the quantitative and qualitative uptake of triglycerides was increased in both endothelial and macrophage cells when exposed to LDL-MAA compared to LDL alone. The results of these studies demonstrate that different MAA-adducts elicit unique responses in different cell types. Additionally, the presence of MAA appears to modulate the cells leading to increased uptake of triglycerides and further progression of the inflammatory response.https://digitalcommons.unmc.edu/emet_posters/1003/thumbnail.jp
Theoretical search for Chevrel phase based thermoelectric materials
We investigate the thermoelectric properties of some semiconducting Chevrel
phases. Band structure calculations are used to compute thermopowers and to
estimate of the effects of alloying and disorder on carrier mobility. Alloying
on the Mo site with transition metals like Re, Ru or Tc to reach a
semiconducting composition causes large changes in the electronic structure at
the Fermi level. Such alloys are expected to have low carrier mobilities.
Filling with transition metals was also found to be incompatible with high
thermoelectric performance based on the calculated electronic structures.
Filling with Zn, Cu, and especially with Li was found to be favorable. The
calculated electronic structures of these filled Chevrel phases are consistent
with low scattering of carriers by defects associated with the filling. We
expect good mobility and high thermopower in materials with the composition
close to (Li,Cu)MoSe, particularly when Li-rich, and recommend this
system for experimental investigation.Comment: 4 two-column pages, 4 embedded ps figure
An analysis of Liberia's 2007 national health policy: lessons for health systems strengthening and chronic disease care in poor, post-conflict countries
<p>Abstract</p> <p>Background</p> <p>Globally, chronic diseases are responsible for an enormous burden of deaths, disability, and economic loss, yet little is known about the optimal health sector response to chronic diseases in poor, post-conflict countries. Liberia's experience in strengthening health systems and health financing overall, and addressing HIV/AIDS and mental health in particular, provides a relevant case study for international stakeholders and policymakers in other poor, post-conflict countries seeking to understand and prioritize the global response to chronic diseases.</p> <p>Methods</p> <p>We conducted a historical review of Liberia's post-conflict policies and their impact on general economic and health indicators, as well as on health systems strengthening and chronic disease care and treatment. Key sources included primary documents from Liberia's Ministry of Health and Social Welfare, published and gray literature, and personal communications from key stakeholders engaged in Liberia's Health Sector Reform. In this case study, we examine the early reconstruction of Liberia's health care system from the end of conflict in 2003 to the present time, highlight challenges and lessons learned from this initial experience, and describe future directions for health systems strengthening and chronic disease care and treatment in Liberia.</p> <p>Results</p> <p>Six key lessons emerge from this analysis: (i) the 2007 National Health Policy's 'one size fits all' approach met aggregate planning targets but resulted in significant gaps and inefficiencies throughout the system; (ii) the innovative Health Sector Pool Fund proved to be an effective financing mechanism to recruit and align health actors with the 2007 National Health Policy; (iii) a substantial rural health delivery gap remains, but it could be bridged with a robust cadre of community health workers integrated into the primary health care system; (iv) effective strategies for HIV/AIDS care in other settings should be validated in Liberia and adapted for use in other chronic diseases; (v) mental health disorders are extremely prevalent in Liberia and should remain a top chronic disease priority; and (vi) better information systems and data management are needed at all levels of the health system.</p> <p>Conclusions</p> <p>The way forward for chronic diseases in Liberia will require an increased emphasis on quality over quantity, better data management to inform rational health sector planning, corrective mechanisms to more efficiently align health infrastructure and personnel with existing needs, and innovative methods to improve long-term retention in care and bridge the rural health delivery gap.</p
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