76 research outputs found

    Limits on asymmetric orthopositronium formation in high Z optically active molecules

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    The proposed connection between the parity violating handedness of beta particles in radioactive decay and the sign (L) of biological chirality (the Vester-Ulbricht [V-U] hypothesis) is experimentally tested. The theoretically predicted asymmetry in triplet positronium formation ( A Ps ) is measured in several high Z optically active molecules using low energy positrons with a net helicity. We find A Ps A Ps >2×10 −6 in these molecules. The connection between these limits and limits on asymmetric radiolysis ( A R ) is made, with a new limit of A R >10 −9 being placed. This limit on A R , which is thirty times lower than a previous measurement in the amino acid leucine ( Z =6), is still not small enough to rule out the V-U hypothesis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43348/1/11084_2005_Article_BF01808051.pd

    Radiative corrections in the Zeeman effect of 2 3P states of helium

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    Radiative corrections using third-order perturbation theory are considered in a theoretical calculation of the Zeeman effect. The corrections have been calculated for the states 23P of helium, and found to be of the same order as other radiative corrections calculated by Anthony and Sebastian [Phys. Rev. A 48, 3792 (1993)]

    Dissociation in a polymerization model of homochirality

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    A fully self-contained model of homochirality is presented that contains the effects of both polymerization and dissociation. The dissociation fragments are assumed to replenish the substrate from which new monomers can grow and undergo new polymerization. The mean length of isotactic polymers is found to grow slowly with the normalized total number of corresponding building blocks. Alternatively, if one assumes that the dissociation fragments themselves can polymerize further, then this corresponds to a strong source of short polymers, and an unrealistically short average length of only 3. By contrast, without dissociation, isotactic polymers becomes infinitely long.Comment: 16 pages, 6 figures, submitted to Orig. Life Evol. Biosp

    g factor of Li-like ions with nonzero nuclear spin

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    The fully relativistic theory of the g factor of Li-like ions with nonzero nuclear spin is considered for the (1s)^2 2s state. The magnetic-dipole hyperfine-interaction correction to the atomic g factor is calculated including the one-electron contributions as well as the interelectronic-interaction effects of order 1/Z. This correction is combined with the interelectronic-interaction, QED, nuclear recoil, and nuclear size corrections to obtain high-precision theoretical values for the g factor of Li-like ions with nonzero nuclear spin. The results can be used for a precise determination of nuclear magnetic moments from g factor experiments.Comment: 20 pages, 5 figure

    Homochiral growth through enantiomeric cross-inhibition

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    The stability and conservation properties of a recently proposed polymerization model are studied. The achiral (racemic) solution is linearly unstable once the relevant control parameter (here the fidelity of the catalyst) exceeds a critical value. The growth rate is calculated for different fidelity parameters and cross-inhibition rates. A chirality parameter is defined and shown to be conserved by the nonlinear terms of the model. Finally, a truncated version of the model is used to derive a set of two ordinary differential equations and it is argued that these equations are more realistic than those used in earlier models of that form.Comment: 20 pages, 6 figures, Orig. Life Evol. Biosph. (accepted

    Spin-polarized low-energy positron beams and their applications

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    The production and use of low-energy (100 eV to 5 keV) high-intensity, spin-polarized positron beams is reviewed. Methods for obtaining beams with high polarization are discussed. Applications include studies of the moderation process, surface and bulk magnetism, optically active molecules, and the production of polarized anti-protons.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47033/1/339_2004_Article_BF00635183.pd

    Isolation and Maintenance-Free Culture of Contractile Myotubes from Manduca sexta Embryos

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    Skeletal muscle tissue engineering has the potential to treat tissue loss and degenerative diseases. However, these systems are also applicable for a variety of devices where actuation is needed, such as microelectromechanical systems (MEMS) and robotics. Most current efforts to generate muscle bioactuators are focused on using mammalian cells, which require exacting conditions for survival and function. In contrast, invertebrate cells are more environmentally robust, metabolically adaptable and relatively autonomous. Our hypothesis is that the use of invertebrate muscle cells will obviate many of the limitations encountered when mammalian cells are used for bioactuation. We focus on the tobacco hornworm, Manduca sexta, due to its easy availability, large size and well-characterized muscle contractile properties. Using isolated embryonic cells, we have developed culture conditions to grow and characterize contractile M. sexta muscles. The insect hormone 20-hydroxyecdysone was used to induce differentiation in the system, resulting in cells that stained positive for myosin, contract spontaneously for the duration of the culture, and do not require media changes over periods of more than a month. These cells proliferate under normal conditions, but the application of juvenile hormone induced further proliferation and inhibited differentiation. Cellular metabolism under normal and low glucose conditions was compared for C2C12 mouse and M. sexta myoblast cells. While differentiated C2C12 cells consumed glucose and produced lactate over one week as expected, M. sexta muscle did not consume significant glucose, and lactate production exceeded mammalian muscle production on a per cell basis. Contractile properties were evaluated using index of movement analysis, which demonstrated the potential of these cells to perform mechanical work. The ability of cultured M. sexta muscle to continuously function at ambient conditions without medium replenishment, combined with the interesting metabolic properties, suggests that this cell source is a promising candidate for further investigation toward bioactuator applications

    New Estimates Of Asymmetric Decomposition Of Racemic Mixtures By Natural Beta-radiation Sources

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62979/1/313391a0.pd
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