194 research outputs found

    Dynamic Demand Analysis of India Domestic Coffee Market

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    Coffee, although an important commodity in India agricultural exports, has faced fluctuating international prices and decreasing unit value realisation, especially in the post-reform period. Hence, domestic market for coffee cannot be neglected altogether. In fact, Coffee Board has proposed a promotional campaign to increase domestic demand for coffee. In this context, it becomes necessary to understand weather the emphasis should be on price incentives or nonprice factors. We estimate coffee demand for the Indian domestic market using the dynamic error-correction methodology (ECM). Results show that while demand for coffee is inelastic in the long-run, it is highly inelastic in the short-run. This suggests that Coffee Board may focus efforts on non-price factors rather than price incentives in their generic coffee promotional campaign.

    An Analysis of Farmers’ Perception and Awareness towards Crop Insurance as a Tool for Risk Management in Tamil Nadu

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    To insulate farmers against risks in agriculture, government has launched several schemes such as National Agricultural Insurance Scheme and weather index based crop insurance schemes. But their coverage seems to be limited among the farmers primarily due to lack of full information. This paper has reported the results of a survey of 600 farmers conducted to assess their perception about various facets of crop insurance schemes. The Probit and Tobit models have been employed to analyse the factors affecting awareness among the farmers. Crop diversification index has also been used to examine the farmers’ adjustment mechanism against risks. The survey has revealed that most farmers (65%) are aware of risk mitigation measures of the government. But, only half of the farmers have been found aware about the crop insurance schemes/products. This implies that there is need to disseminate information about insurance schemes across the target groups. Further, it has been shown that factors such as gross cropped area, income from other than agricultural sources, presence of risk in farming, number of workers in the farm family, satisfaction with the premium rate and affordability of the insurance premium amount significantly and positively influence the adoption of insurance and premium paid by the farmers. The study has clearly brought out the urgency of developing more innovative products, having minimum human interventions.Crop insurance, Risk management, Crop diversification index, Agricultural and Food Policy, Q14, Q18,

    Spatial particulate fields during highwinds in the imperial valley, California

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    We examined windblown dust within the Imperial Valley (CA) during strong springtime west-southwesterly (WSW) wind events. Analysis of routine agency meteorological and ambient particulate matter (PM) measurements identified 165 high WSW wind events between March and June 2013 to 2019. The PM concentrations over these days are higher at northern valley monitoring sites, with daily PM mass concentration of particles less than 10 micrometers aerodynamic diameter (PM10) at these sites commonly greater than 100 ÎĽg/m3 and reaching around 400 ÎĽg/m3, and daily PM mass concentration of particles less than 2.5 micrometers aerodynamic diameter (PM2.5) commonly greater than 20 ÎĽg/m3 and reaching around 60 ÎĽg/m3. A detailed analysis utilizing 1 km resolution multi-angle implementation of atmospheric correction (MAIAC) aerosol optical depth (AOD), Identifying Violations Affecting Neighborhoods (IVAN) low-cost PM2.5 measurements and 500 m resolution sediment supply fields alongside routine ground PM observations identified an area of high AOD/PM during WSW events spanning the northwestern valley encompassing the Brawley/Westmorland through the Niland area. This area shows up most clearly once the average PM10 at northern valley routine sites during WSW events exceeds 100 ÎĽg/m3. The area is consistent with high soil sediment supply in the northwestern valley and upwind desert, suggesting local sources are primarily responsible. On the basis of this study, MAIAC AOD appears able to identify localized high PM areas during windblown dust events provided the PM levels are high enough. The use of the IVAN data in this study illustrates how a citizen science effort to collect more spatially refined air quality concentration data can help pinpoint episodic pollution patterns and possible sources important for PM exposure and adverse health effects

    Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents.

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    Novel N-phenylindazole based diarylureas have been designed, synthesized and evaluated as potential anticancer agents. In vitro cell viability studies of these derivatives illustrate good potency with IC50 values in the range of 0.4–50 μM in several cancer cell lines including murine metastatic breast cancer 4T1, murine glioblastoma GL261, human triple negative breast cancer MDA-MB-231, human pancreatic cancer MIAPaCa-2, and human colorectal cancer cell line WiDr. The ester group in the lead compound 8i was modified to incorporate amino-amides to increase solubility and stability while retaining biological activity. Further in vitro studies reveal that lead candidates inhibit tube length in HUVEC cells. In vivo systemic toxicity studies indicate that these candidate compounds are well tolerated in mice without any significant side effects. Anticancer efficacy studies in WiDr tumor xenograft and 4T1 tumor syngraft models demonstrate that the lead candidate 11 exhibits significant antitumor properties as a single agent in these tumor models

    Experiences from the Missouri Antimicrobial Stewardship Collaborative: A mixed methods study

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    We performed a mixed-methods study to evaluate antimicrobial stewardship program (ASP) uptake and to assess variability of program implementation in Missouri hospitals. Despite increasing uptake of ASPs in Missouri, there is wide variability in both the scope and sophistication of these programs

    Modeling Methods for Discrete Choice Analysis

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    This paper introduces new forms, sampling and estimation approaches fordiscrete choice models. The new models include behavioral specifications oflatent class choice models, multinomial probit, hybrid logit, andnon-parametric methods. Recent contributions also include new specializedchoice based sample designs that permit greater efficiency in datacollection. Finally, the paper describes recent developments in the use ofsimulation methods for model estimation. These developments are designed toallow the applications of discrete choice models to a wider variety ofdiscrete choice problems.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47225/1/11002_2004_Article_138116.pd

    Emission factors from road dust resuspension in a Mediterranean freeway

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    Particulate matter emissions from paved roads are currently one of the main challenges for a sustainable transport in Europe. Emissions are scarcely estimated due to the lack of knowledge about the resuspension process severely hampering a reliable simulation of PM and heavy metals concentrations in large cities and evaluation of population exposure. In this study the Emission Factors from road dust resuspension on a Mediterranean freeway were estimated per single vehicle category and PM component (OC, EC, mineral dust and metals) by means of the deployment of vertical profiles of passive samplers and terminal concentration estimate. The estimated PM10 emission factors varied from 12 to 47 mg VKT?1 (VKT: Vehicle Kilometer Traveled) with an average value of 22.7 ? 14.2 mg VKT?1. Emission Factors for heavy and light duty vehicles, passenger cars and motorbikes were estimated, based on average fleet composition and EPA ratios, in 187e733 mg VKT?1, 33e131 VKT?1, 9.4e36.9 VKT?1 and 0.8e3.3 VKT?1, respectively. These range of values are lower than previous estimates in Mediterranean urban roads, probably due to the lower dust reservoir on freeways. PM emitted material was dominated by mineral dust (9e10 mg VKT?1), but also OC and EC were found to be major components and approximately 14 e25% and 2e9% of average PM exhaust emissions from diesel passenger cars on highways respectively

    The Fission Yeast XMAP215 Homolog Dis1p Is Involved in Microtubule Bundle Organization

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    Microtubules are essential for a variety of fundamental cellular processes such as organelle positioning and control of cell shape. Schizosaccharomyces pombe is an ideal organism for studying the function and organization of microtubules into bundles in interphase cells. Using light microscopy and electron tomography we analyzed the bundle organization of interphase microtubules in S. pombe. We show that cells lacking ase1p and klp2p still contain microtubule bundles. In addition, we show that ase1p is the major determinant of inter-microtubule spacing in interphase bundles since ase1 deleted cells have an inter-microtubule spacing that differs from that observed in wild-type cells. We then identified dis1p, a XMAP215 homologue, as factor that promotes the stabilization of microtubule bundles. In wild-type cells dis1p partially co-localized with ase1p at regions of microtubule overlap. In cells deleted for ase1 and klp2, dis1p accumulated at the overlap regions of interphase microtubule bundles. In cells lacking all three proteins, both microtubule bundling and inter-microtubule spacing were further reduced, suggesting that Dis1p contributes to interphase microtubule bundling
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