106 research outputs found

    The Field of Marriage: Cultural Capital and Women’s Submissiveness in the Light of Pierre Bourdieu

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    Since the dawn of history, women have always been subjected to and condemned by men’s will; their choices and power have been limited by men’s authority and domination in patriarchal societies due to their gender. This paper examines Elizabeth Gaskell’s Wives and Daughters and Parinoush Saniee’s The Book of Fate and demonstrates a reciprocal relationship between cultural capital and women’s subordination in the marriage field, the analysis of which will be based on Pierre Bourdieu’s theoretical concepts of field, capital, and habitus. Drawing on Bourdieu’s theoretical concepts as well as the contextual analysis of the selected novels, the findings of this paper indicate that women’s submissiveness, present in different patriarchal societies throughout history, is the outcome of men’s use of culture as a sort of capital to retain and reproduce their power and domination in all fields, even those related to women, including the field of marriage

    The ethical identity of law students

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    This is the author accepted manuscript. The final version is available from the publisher via the DOI in this recordThis paper uses measures of values, moral outlook and professional identity to explore the ethical and professional identity of law students. We do so in two jurisdictions, surveying 441 students studying in England and Wales and 569 students studying in the US. The survey covers the first and final years of an undergraduate law degree and the postgraduate vocational stage in England and Wales, as well as students in all years of the JD programme in the US. We explore whether law students towards the end of their legal education have ethical identities predictive of less ethical conduct than those at the beginning of their legal education; whether law students intending careers in business law have values and profiles consistent with less ethical conduct than those intending to work for government or individuals; and what factors might explain these differences in ethical outlook. Our findings suggest that ethical identity is strongly associated with gender and career intentions. They also suggest weaker moral identities for students intending to practise business law. Ultimately, our findings support a conclusion that is more nuanced than the predominant theses about the impact of legal education on student ethicality which tend to suggest legal education diminishes ethicality

    Bridging the gap: Attending to discontinuity in identification of multiword expressions

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    We introduce a new method to tag Multiword Expressions (MWEs) using a linguistically interpretable language-independent deep learning architecture. We specifically target discontinuity, an under-explored aspect that poses a significant challenge to computational treatment of MWEs. Two neural architectures are explored: Graph Convolutional Network (GCN) and multi-head self-attention. GCN leverages dependency parse information, and self-attention attends to long-range relations. We finally propose a combined model that integrates complementary information from both through a gating mechanism. The experiments on a standard multilingual dataset for verbal MWEs show that our model outperforms the baselines not only in the case of discontinuous MWEs but also in overall F-score

    A Multi Expert Decision Support Tool for the Evaluation of Advanced Wastewater Treatment Trains: A Novel Approach to Improve Urban Sustainability

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    This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Wastewater Treatment (WWT) for water reuse applications has been accepted as a strategic solution in improving water supplies across the globe; however, there are still various challenges that should be overcome. Selection of practical solutions is then required whilst considering technical, environmental, socio-cultural, and financial factors. In this study, a multi expert decision support tool that considers a variety of evaluation criteria is proposed to provide a ranking system for competing advanced WWT technologies in terms of their performance. Two scenarios of water reuse in the contexts of Brazil and Greece are defined, and evaluation is undertaken based on opinions of water reuse experts. The results prove that the tool would successfully facilitate rigorous and methodical analysis in evaluation of WWT technologies for water reuse applications with potential for use under various sets of evaluation criteria, WWT technologies and contexts

    Melatonin and Parkinson Disease: Current Status and Future Perspectives for Molecular Mechanisms

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    Parkinson disease (PD) is a chronic and neurodegenerative disease with motor and nonmotor symptoms. Multiple pathways are involved in the pathophysiology of PD, including apoptosis, autophagy, oxidative stress, inflammation, α-synuclein aggregation, and changes in the neurotransmitters. Preclinical and clinical studies have shown that melatonin supplementation is an appropriate therapy for PD. Administration of melatonin leads to inhibition of some pathways related to apoptosis, autophagy, oxidative stress, inflammation, α-synuclein aggregation, and dopamine loss in PD. In addition, melatonin improves some nonmotor symptom in patients with PD. Limited studies, however, have evaluated the role of melatonin on molecular mechanisms and clinical symptoms in PD. This review summarizes what is known regarding the impact of melatonin on PD in preclinical and clinical studies. © 2019, Springer Science+Business Media, LLC, part of Springer Nature

    Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial

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    Background and aims: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic and selenium co-supplementation on cognitive function and metabolic status among patients with AD. Methods: This randomized, double-blind, controlled clinical trial was conducted among 79 patients with AD. Patients were randomly assigned to receive either selenium (200 μg/day) plus probiotic containing Lactobacillus acidophilus, Bifidobacterium bifidum, and Bifidobacterium longum (2 × 109 CFU/day each) (n = 27), selenium (200 μg/day) (n = 26) or placebo (n = 26) for 12 weeks. Results: Selenium supplementation, compared with the placebo, significantly reduced serum high sensitivity C-reactive protein (hs-CRP) (P < 0.001), insulin (P = 0.001), homeostasis model of assessment-insulin resistance (HOMA-IR) (P = 0.002), LDL-cholesterol (P = 0.04) and total-/HDL-cholesterol ratio (P = 0.004), and significantly increased total glutathione (GSH) (P = 0.001) and the quantitative insulin sensitivity check index (QUICKI) (P = 0.01). Compared with only selenium and placebo, probiotic and selenium co-supplementation resulted in a significant increase in mini-mental state examination score (+1.5 ± 1.3 vs. +0.5 ± 1.2 and −0.2 ± 1.1, respectively, P < 0.001). Probiotic plus selenium intake resulted in a significant reduction in hs-CRP (−1.6 ± 1.4 vs. −0.8 ± 1.0 and +0.1 ± 0.5 mg/L, respectively, P < 0.001), and a significant increase in total antioxidant capacity (+89.4 ± 129.6 vs. +20.0 ± 62.5 and −0.7 ± 27.2 mmol/L, respectively, P = 0.001) and GSH (+122.8 ± 136.5 vs. +102.2 ± 135.2 and +1.5 ± 53.2 μmol/L, respectively, P = 0.001) compared with only selenium and placebo. In addition, subjects who received probiotic plus selenium supplements had significantly lower insulin levels (−2.1 ± 2.5 vs. −1.0 ± 1.3 and +0.7 ± 2.0 μIU/mL, respectively, P < 0.001), HOMA-IR (−0.5 ± 0.6 vs. −0.2 ± 0.3 and +0.1 ± 0.4, respectively, P < 0.001), and higher QUICKI (+0.01 ± 0.01 vs. +0.005 ± 0.007 and −0.002 ± 0.01, respectively, P < 0.006) compared with only selenium and placebo. Additionally, probiotic and selenium co-supplementation resulted in a significant reduction in serum triglycerides (−17.9 ± 26.1 vs. −3.5 ± 33.9 and +0.3 ± 9.3 mg/dL, respectively, P = 0.02), VLDL- (−3.6 ± 5.2 vs. −0.7 ± 6.8 and +0.05 ± 1.8 mg/dL, respectively, P = 0.02), LDL- (−8.8 ± 17.8 vs. −8.1 ± 19.2 and +2.7 ± 19.0 mg/dL, respectively, P = 0.04) and total-/HDL-cholesterol (−0.3 ± 0.7 vs. −0.4 ± 0.9 and +0.3 ± 0.6, respectively, P = 0.005) compared with only selenium and placebo. Conclusions: Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles. This study was registered in the Iranian website (www.irct.ir) for registration of clinical trial

    Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial

    Get PDF
    Background and aims: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic and selenium co-supplementation on cognitive function and metabolic status among patients with AD. Methods: This randomized, double-blind, controlled clinical trial was conducted among 79 patients with AD. Patients were randomly assigned to receive either selenium (200 μg/day) plus probiotic containing Lactobacillus acidophilus, Bifidobacterium bifidum, and Bifidobacterium longum (2 � 109 CFU/day each) (n = 27), selenium (200 μg/day) (n = 26) or placebo (n = 26) for 12 weeks. Results: Selenium supplementation, compared with the placebo, significantly reduced serum high sensitivity C-reactive protein (hs-CRP) (P &lt; 0.001), insulin (P = 0.001), homeostasis model of assessment-insulin resistance (HOMA-IR) (P = 0.002), LDL-cholesterol (P = 0.04) and total-/HDL-cholesterol ratio (P = 0.004), and significantly increased total glutathione (GSH) (P = 0.001) and the quantitative insulin sensitivity check index (QUICKI) (P = 0.01). Compared with only selenium and placebo, probiotic and selenium co-supplementation resulted in a significant increase in mini-mental state examination score (+1.5 ± 1.3 vs. +0.5 ± 1.2 and �0.2 ± 1.1, respectively, P &lt; 0.001). Probiotic plus selenium intake resulted in a significant reduction in hs-CRP (�1.6 ± 1.4 vs. �0.8 ± 1.0 and +0.1 ± 0.5 mg/L, respectively, P &lt; 0.001), and a significant increase in total antioxidant capacity (+89.4 ± 129.6 vs. +20.0 ± 62.5 and �0.7 ± 27.2 mmol/L, respectively, P = 0.001) and GSH (+122.8 ± 136.5 vs. +102.2 ± 135.2 and +1.5 ± 53.2 μmol/L, respectively, P = 0.001) compared with only selenium and placebo. In addition, subjects who received probiotic plus selenium supplements had significantly lower insulin levels (�2.1 ± 2.5 vs. �1.0 ± 1.3 and +0.7 ± 2.0 μIU/mL, respectively, P &lt; 0.001), HOMA-IR (�0.5 ± 0.6 vs. �0.2 ± 0.3 and +0.1 ± 0.4, respectively, P &lt; 0.001), and higher QUICKI (+0.01 ± 0.01 vs. +0.005 ± 0.007 and �0.002 ± 0.01, respectively, P &lt; 0.006) compared with only selenium and placebo. Additionally, probiotic and selenium co-supplementation resulted in a significant reduction in serum triglycerides (�17.9 ± 26.1 vs. �3.5 ± 33.9 and +0.3 ± 9.3 mg/dL, respectively, P = 0.02), VLDL- (�3.6 ± 5.2 vs. �0.7 ± 6.8 and +0.05 ± 1.8 mg/dL, respectively, P = 0.02), LDL- (�8.8 ± 17.8 vs. �8.1 ± 19.2 and +2.7 ± 19.0 mg/dL, respectively, P = 0.04) and total-/HDL-cholesterol (�0.3 ± 0.7 vs. �0.4 ± 0.9 and +0.3 ± 0.6, respectively, P = 0.005) compared with only selenium and placebo. Conclusions: Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles. This study was registered in the Iranian website (www.irct.ir) for registration of clinical trials (http://www.irct.ir: IRCT20170612034497N5). © 2018 Elsevier Ltd and European Society for Clinical Nutrition and Metabolis

    Multiview classification and dimensionality reduction of scalp and intracranial EEG data through tensor factorisation

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    Electroencephalography (EEG) signals arise as a mixture of various neural processes that occur in different spatial, frequency and temporal locations. In classification paradigms, algorithms are developed that can distinguish between these processes. In this work, we apply tensor factorisation to a set of EEG data from a group of epileptic patients and factorise the data into three modes; space, time and frequency with each mode containing a number of components or signatures. We train separate classifiers on various feature sets corresponding to complementary combinations of those modes and components and test the classification accuracy of each set. The relative influence on the classification accuracy of the respective spatial, temporal or frequency signatures can then be analysed and useful interpretations can be made. Additionaly, we show that through tensor factorisation we can perform dimensionality reduction by evaluating the classification performance with regards to the number mode components and by rejecting components with insignificant contribution to the classification accuracy

    Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial

    Get PDF
    Background and aims: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic and selenium co-supplementation on cognitive function and metabolic status among patients with AD. Methods: This randomized, double-blind, controlled clinical trial was conducted among 79 patients with AD. Patients were randomly assigned to receive either selenium (200 μg/day) plus probiotic containing Lactobacillus acidophilus, Bifidobacterium bifidum, and Bifidobacterium longum (2 � 109 CFU/day each) (n = 27), selenium (200 μg/day) (n = 26) or placebo (n = 26) for 12 weeks. Results: Selenium supplementation, compared with the placebo, significantly reduced serum high sensitivity C-reactive protein (hs-CRP) (P &lt; 0.001), insulin (P = 0.001), homeostasis model of assessment-insulin resistance (HOMA-IR) (P = 0.002), LDL-cholesterol (P = 0.04) and total-/HDL-cholesterol ratio (P = 0.004), and significantly increased total glutathione (GSH) (P = 0.001) and the quantitative insulin sensitivity check index (QUICKI) (P = 0.01). Compared with only selenium and placebo, probiotic and selenium co-supplementation resulted in a significant increase in mini-mental state examination score (+1.5 ± 1.3 vs. +0.5 ± 1.2 and �0.2 ± 1.1, respectively, P &lt; 0.001). Probiotic plus selenium intake resulted in a significant reduction in hs-CRP (�1.6 ± 1.4 vs. �0.8 ± 1.0 and +0.1 ± 0.5 mg/L, respectively, P &lt; 0.001), and a significant increase in total antioxidant capacity (+89.4 ± 129.6 vs. +20.0 ± 62.5 and �0.7 ± 27.2 mmol/L, respectively, P = 0.001) and GSH (+122.8 ± 136.5 vs. +102.2 ± 135.2 and +1.5 ± 53.2 μmol/L, respectively, P = 0.001) compared with only selenium and placebo. In addition, subjects who received probiotic plus selenium supplements had significantly lower insulin levels (�2.1 ± 2.5 vs. �1.0 ± 1.3 and +0.7 ± 2.0 μIU/mL, respectively, P &lt; 0.001), HOMA-IR (�0.5 ± 0.6 vs. �0.2 ± 0.3 and +0.1 ± 0.4, respectively, P &lt; 0.001), and higher QUICKI (+0.01 ± 0.01 vs. +0.005 ± 0.007 and �0.002 ± 0.01, respectively, P &lt; 0.006) compared with only selenium and placebo. Additionally, probiotic and selenium co-supplementation resulted in a significant reduction in serum triglycerides (�17.9 ± 26.1 vs. �3.5 ± 33.9 and +0.3 ± 9.3 mg/dL, respectively, P = 0.02), VLDL- (�3.6 ± 5.2 vs. �0.7 ± 6.8 and +0.05 ± 1.8 mg/dL, respectively, P = 0.02), LDL- (�8.8 ± 17.8 vs. �8.1 ± 19.2 and +2.7 ± 19.0 mg/dL, respectively, P = 0.04) and total-/HDL-cholesterol (�0.3 ± 0.7 vs. �0.4 ± 0.9 and +0.3 ± 0.6, respectively, P = 0.005) compared with only selenium and placebo. Conclusions: Overall, we found that probiotic and selenium co-supplementation for 12 weeks to patients with AD improved cognitive function and some metabolic profiles. This study was registered in the Iranian website (www.irct.ir) for registration of clinical trials (http://www.irct.ir: IRCT20170612034497N5). © 2018 Elsevier Ltd and European Society for Clinical Nutrition and Metabolis
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