192 research outputs found
Supplementary data for article: FilipoviÄ, N. R.; Borna, M.; KlisuriÄ, O.; Pregelj, M.; JagodiÄ, M.; AnÄelkoviÄ, K. K.; TodoroviÄ, T. Synthesis, Characterization, and Thermal Behavior of Cu(II) and Zn(II) Complexes with (E)-2-[N-(1-Pyridin-2-Yl-Ethylidene)Hydrazino]Acetic Acid (AphaOH). Crystal Structure of [Zn-2(AphaO)(2)Cl-2]. Journal of Coordination Chemistry 2013, 66 (9), 1549ā1560. https://doi.org/10.1080/00958972.2013.786052
Supplementary material for: [https://doi.org/10.1080/00958972.2013.786052]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1639
A.R.G! Augmented Reality and Gait: Analyzing the Influence of Cues on Gait Patterns in Augmented Reality
Use of Augmented Reality (AR) technology for rehabilitation has drastically increased in recent years. While theoretically AR can be used to cue gait adaptations such as changes to step length and cadence through visual and auditory cues, it is still unknown how people respond to the technology. PURPOSE: To assess the feasibility of external visual and auditory cues delivered through AR on spatiotemporal gait outcomes in a healthy, young population. METHODS: 20 healthy participants between age 18 and 35 were screened and recruited to perform randomized gait trials consisting of four different cueing conditions. The participants wore a Magic Leap One AR headset with a custom-designed cueing application. Participants were instructed to walk 10 steps under one of four cueing conditions provided by the AR application: No Cues (NC) (i.e., natural gait), Visual (V), Auditory (A), and Visual and Auditory (VA). Each condition was completed three times in a randomized order for a total of 12 trials per participant. An Inertial Measurement Unit (IMU) system was used to collect spatiotemporal gait data. A System Usability Survey (SUS) was administered after each participant completed their trials to determine the usability of our novel application and to determine whether the reported usability of the system was related to changes in gait variability. RESULTS: Preliminary results indicate all cueing conditions exhibited a significantly faster cadence compared to NC trials. Surprisingly, the cadence variability increased across all A trials. Increased system usability SUS results were significantly correlated with increased percent stance variability across A trials. V trials exhibited significantly decreased stride lengths compared to NC. Combined (AV) cues had no effect on gait outcomes. CONCLUSION: Our findings reinforced that certain visual and auditory cues affect gait parameters, albeit in a direction opposite of what was expected (e.g., greater cadence variability with auditory cues). These results provide insight into how healthy populations respond to cues delivered through AR, as well as provide a foundation for future studies to implement this technology with clinical populations such as those with Parkinsonās disease
Influence of nuclear radiation and laser beams on optical fibers and components
The influence of nuclear radiation and particles has been the object of investigation for a long time. For new materials and systems the research should be continued. Human activities in various environments, including space, call for more detailed research. The role of fibers in contemporary communications, medicine, and industry increases. Fibers, their connections and fused optics components have one type of tasks - the transmission of information and power. The other type of tasks is reserved for fiber lasers: quantum generators and amplifiers. The third type of tasks is for fiber sensors, including high energy nuclear physics. In this paper we present some chosen topics in the mentioned areas as well as our experiments with nuclear radiation and laser beams to fiber and bulk materials of various nature (glass, polymer, metallic, etc.)
Laser interactions with bundle fiber structures
Laser damages of materials are in research focus during the last decade. These terms can be understood as useful in the treatment of materials or in theoretical modeling of interactions of laser beams with the material. Also, they can be destructive when it comes to high power density where the nonlinear effects are present, too. In addition to the theory, many detailed experimental work is required for new optical components applications. The experiments with Nd 3+ : YAG laser (1.064 Āµm) with defined working regime and power densities and specifically developed optical fiber bundles are the subject of this paper. The fibers are developed in laboratory conditions for specific purposes. Also, commercial optical fiber bundle for dental use are presented and discussed as comparison with the same laser types
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
The design of compounds that can discriminate between closely related target proteins remains a central challenge in drug discovery. Specific therapeutics targeting the highly conserved myosin motor family are urgently needed as mutations in at least six of its members cause numerous diseases. Allosteric modulators, like the myosin-II inhibitor blebbistatin, are a promising means to achieve specificity. However, it remains unclear why blebbistatin inhibits myosin-II motors with different potencies given that it binds at a highly conserved pocket that is always closed in blebbistatin-free experimental structures. We hypothesized that the probability of pocket opening is an important determinant of the potency of compounds like blebbistatin. To test this hypothesis, we used Markov state models (MSMs) built from over 2 ms of aggregate molecular dynamics simulations with explicit solvent. We find that blebbistatin\u27s binding pocket readily opens in simulations of blebbistatin-sensitive myosin isoforms. Comparing these conformational ensembles reveals that the probability of pocket opening correctly identifies which isoforms are most sensitive to blebbistatin inhibition and that docking against MSMs quantitatively predicts blebbistatin binding affinities (
Supplementary data for article: FilipoviÄ, N. R.; Borna, M.; KlisuriÄ, O.; Pregelj, M.; JagodiÄ, M.; AnÄelkoviÄ, K. K.; TodoroviÄ, T. Synthesis, Characterization, and Thermal Behavior of Cu(II) and Zn(II) Complexes with (E)-2-[N-(1-Pyridin-2-Yl-Ethylidene)Hydrazino]Acetic Acid (AphaOH). Crystal Structure of [Zn-2(AphaO)(2)Cl-2]. Journal of Coordination Chemistry 2013, 66 (9), 1549ā1560. https://doi.org/10.1080/00958972.2013.786052
Supplementary material for: [https://doi.org/10.1080/00958972.2013.786052]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1639
Physiciansā and nursesā decision making to encounter neonates with poor prognosis in the neonatal intensive care unit
This is an Accepted Manuscript of an article published by Sage in Clinical Ethics on 03/06/2020. Available online: https://journals.sagepub.com/doi/abs/10.1177/1477750920927173This is an Accepted Manuscript of an article published by Sage in Clinical Ethics on 03/06/2020.Available online: https://journals.sagepub.com/doi/abs/10.1177/1477750920927173acceptedVersio
Neural Correlates of Verb Argument Structure Processing
This fMRI study examined the neural correlates of verbs controlled for argument structure complexity and nouns controlled for semantic class. Participants showed activation of left inferior frontal and posterior temporal regions for verbs as compared to nouns, and more widespread, non-perisylvian activation for nouns as compared to verbs. Verbs with more complex argument structure entries activated posterior temporal regions bilaterally. These findings suggest that posterior perisylvian regions are crucial for processing the argument structure information associated with verbs
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