Load deflection characteristics of inflated structures

A single, closed form relationship to relate load to the deformed dimensions of the horizontal torus was developed. Wall elasticity was included in the analysis, and special care was taken to predict the final footprint area of the loaded structure. The test fixture utilized is shown. The tori used for the bulk of the testing were rubber inner tubes for a 32 and 160 pneumatic tire. The inner tube being tested was plumbed, to a mercury-filled manometer, which had a 50 inch measurement capacity, by use of a special adapter. The adapter fit over the valve stem and allowed air to be added from a shop-air source and to be bled through the standard valve mechanism. In this fashion, tests requiring the maintenance of a constant indication of air pressure could be run with little difficulty

Intensity limits of the PSI Injector II cyclotron

We investigate limits on the current of the PSI Injector II high intensity separate-sector isochronous cyclotron, in its present configuration and after a proposed upgrade. Accelerator Driven Subcritical Reactors, neutron and neutrino experiments, and medical isotope production all benefit from increases in current, even at the ~ 10% level: the PSI cyclotrons provide relevant experience. As space charge dominates at low beam energy, the injector is critical. Understanding space charge effects and halo formation through detailed numerical modelling gives clues on how to maximise the extracted current. Simulation of a space-charge dominated low energy high intensity (9.5 mA DC) machine, with a complex collimator set up in the central region shaping the bunch, is not trivial. We use the OPAL code, a tool for charged-particle optics calculations in large accelerator structures and beam lines, including 3D space charge. We have a precise model of the present production) Injector II, operating at 2.2 mA current. A simple model of the proposed future (upgraded) configuration of the cyclotron is also investigated. We estimate intensity limits based on the developed models, supported by fitted scaling laws and measurements. We have been able to perform more detailed analysis of the bunch parameters and halo development than any previous study. Optimisation techniques enable better matching of the simulation set-up with Injector II parameters and measurements. We show that in the production configuration the beam current scales to the power of three with the beam size. However, at higher intensities, 4th power scaling is a better fit, setting the limit of approximately 3 mA. Currents of over 5 mA, higher than have been achieved to date, can be produced if the collimation scheme is adjusted

Transverse-Longitudinal Coupling by Space Charge in Cyclotrons

A method is presented that enables to compute the parameters of matched beams with space charge in cyclotrons with emphasis on the effect of the transverse-longitudinal coupling. Equations describing the transverse-longitudinal coupling and corresponding tune-shifts in first order are derived for the model of an azimuthally symmetric cyclotron. The eigenellipsoid of the beam is calculated and the transfer matrix is transformed into block-diagonal form. The influence of the slope of the phase curve on the transverse-longitudinal coupling is accounted for. The results are generalized and numerical procedures for the case of an AVF cyclotron are presented. The algorithm is applied to the PSI Injector II and Ring cyclotron and the results are compared to TRANSPORT.Comment: 8 pages, 2 figure

A Geometrical Method of Decoupling

The computation of tunes and matched beam distributions are essential steps in the analysis of circular accelerators. If certain symmetries - like midplane symmetrie - are present, then it is possible to treat the betatron motion in the horizontal, the vertical plane and (under certain circumstances) the longitudinal motion separately using the well-known Courant-Snyder theory, or to apply transformations that have been described previously as for instance the method of Teng and Edwards. In a preceeding paper it has been shown that this method requires a modification for the treatment of isochronous cyclotrons with non-negligible space charge forces. Unfortunately the modification was numerically not as stable as desired and it was still unclear, if the extension would work for all thinkable cases. Hence a systematic derivation of a more general treatment seemed advisable. In a second paper the author suggested the use of real Dirac matrices as basic tools to coupled linear optics and gave a straightforward recipe to decouple positive definite Hamiltonians with imaginary eigenvalues. In this article this method is generalized and simplified in order to formulate a straightforward method to decouple Hamiltonian matrices with eigenvalues on the real and the imaginary axis. It is shown that this algebraic decoupling is closely related to a geometric "decoupling" by the orthogonalization of the vectors $\vec E$, $\vec B$ and $\vec P$, that were introduced with the so-called "electromechanical equivalence". We present a structure-preserving block-diagonalization of symplectic or Hamiltonian matrices, respectively. When used iteratively, the decoupling algorithm can also be applied to n-dimensional systems and requires ${\cal O}(n^2)$ iterations to converge to a given precision.Comment: 13 pages, 1 figur

Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts

<p>Abstract</p> <p>Background</p> <p>Exceptionally, a single nucleotide sequence can be translated <it>in vivo </it>in two different frames to yield distinct proteins. In the case of the G-protein alpha subunit XL-alpha-s transcript, a frameshifted open reading frame (ORF) in exon 1 is translated to yield a structurally distinct protein called Alex, which plays a role in platelet aggregation and neurological processes. We carried out a novel bioinformatics screen for other possible dual-frame translated sequences, based on comparative genomics.</p> <p>Results</p> <p>Our method searched human, mouse and rat transcripts in frames +1 and -1 for ORFs which are unusually well conserved at the amino acid level. We name these conserved frameshifted overlapping ORFs 'matreshkas' to reflect their nested character. Select findings of our analysis revealed that the G-protein coupled receptor GPR27 is entirely contained within a frame -1 matreshka, thrombopoietin contains a matreshka which spans ~70% of its length, platelet glycoprotein IIIa (ITGB3) contains a matreshka with the predicted characteristics of a secreted peptide hormone, while the potassium channel KCNK12 contains a matreshka spanning >400 amino acids.</p> <p>Conclusion</p> <p>Although the <it>in vivo </it>existence of translated matreshkas has not been experimentally verified, this genome-wide analysis provides strong evidence that substantial overlapping coding sequences exist in a number of human and rodent transcripts.</p

Spatial and Temporal Variability in MLT Turbulence Inferred from in situ and Ground-Based Observations During the WADIS-1 Sounding Rocket Campaign

In summer 2013 the WADIS-1 sounding rocket campaign was conducted at the Andøya Space Center (ACS) in northern Norway (69° N, 16° E). Among other things, it addressed the question of the variability in mesosphere/lower thermosphere (MLT) turbulence, both in time and space. A unique feature of the WADIS project was multi-point turbulence sounding applying different measurement techniques including rocket-borne ionization gauges, VHF MAARSY radar, and VHF EISCAT radar near Tromsø. This allowed for horizontal variability to be observed in the turbulence field in the MLT at scales from a few to 100 km. We found that the turbulence dissipation rate, ε varied in space in a wavelike manner both horizontally and in the vertical direction. This wavelike modulation reveals the same vertical wavelengths as those seen in gravity waves. We also found that the vertical mean value of radar observations of ε agrees reasonably with rocket-borne measurements. In this way defined 〈εradar〉 value reveals clear tidal modulation and results in variation by up to 2 orders of magnitude with periods of 24 h. The 〈εradar〉 value also shows 12 h and shorter (1 to a few hours) modulations resulting in one decade of variation in 〈εradar〉 magnitude. The 24 h modulation appeared to be in phase with tidal change of horizontal wind observed by SAURA-MF radar. Such wavelike and, in particular, tidal modulation of the turbulence dissipation field in the MLT region inferred from our analysis is a new finding of this work

Coincident measurements of PMSE and NLC above ALOMAR (69° N, 16° E) by radar and lidar from 1999-2008

Polar Mesosphere Summer Echoes (PMSE) and Noctilucent Clouds (NLC) have been routinely measured at the ALOMAR research facility in Northern Norway (69° N, 16° E) by lidar and radar, respectively. 2900 h of lidar measurements by the ALOMAR Rayleigh/Mie/Raman lidar were combined with almost 18 000 h of radar measurements by the ALWIN VHF radar, all taken during the years 1999 to 2008, to study simultaneous and common-volume observations of both phenomena. PMSE and NLC are known from both theory and observations to be positively linked. We quantify the occurrences of PMSE and/or NLC and relations in altitude, especially with respect to the lower layer boundaries. The PMSE occurrence rate is with 75.3% considerably higher than the NLC occurrence rate of 19.5%. For overlapping PMSE and NLC observations, we confirm the coincidence of the lower boundaries and find a standard deviation of 1.26 km, hinting at very fast sublimation rates. However, 10.1% of all NLC measurements occur without accompanying PMSE. Comparison of occurrence rates with solar zenith angle reveals that NLC without PMSE mostly occur around midnight indicating that the ice particles were not detected by the radar due to the reduced electron density

Untersuchungen zur Spezifitätsfrage der heterosynaptischen Facilitation bei Aplysia californica

1. Heterosynaptic facilitation (H.S.F.) could be obtained in 10–15% of all tested nerve cells in the abdominal and left pleural ganglion of Aplysia californica.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47441/1/424_2004_Article_BF00362957.pd

Time course of repetitive heterosynaptic facilitation in Aplysia californica

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/33356/1/0000754.pd