Fault tree analysis and prevention strategies for gas explosion in underground coal mines of Pakistan

Purpose. Gas explosion in the underground coal mines of Pakistan is the main source of coal miners’ mortalities. The purpose of this article is to analyze the main causes of gas explosion in the underground coal mines of Pakistan. Methods. The study employs the Fault Tree Analysis (FTA) to understand the key root causes that lead to system failure. Particularly, this research has articulated the fault tree model in case of gas explosion in underground coal mines to analyze the root causes of this dangerous accident. Findings. This analysis has revealed that most of the root causes (4/7) with 5/10 accidents, 49/53 fatalities and 28/35 injuries resulted from primary failure of the gas explosion that poses a major threat to lives of mine workers. Similarly, the accumulation of gases and ignition are leading causes of gas explosion. Originality. FTA has been employed for the first time to understand the underlying root causes with the corresponding number of accident, fatalities and injuries of gas explosion in underground coal mines of Pakistan. This original application of FTA to the problem under discussion presents some important underlying factors which should be considered to reduce the risk of gas explosion and its related fatal and non-fatal accidents. Practical implications. The study proposes preventive strategies to lessen the fatal and non-fatal accidents resulting from gas explosions. Explicitly, Pakistan has to conduct major structural and safety management reforms.Мета. Аналіз впливу основних факторів, що викликають вибухи шахтного газу метану, на основі складання моделі дерева відмов в умовах вугільних шахт Пакистану. Методика. Для досягнення мети дослідження застосовано емпіричний аналіз вибухів газу у вугільних шахтах Пакистану на основі даних з 2010 по 2018 роки для визначення точного числа аварій зі смертельними випадками і травмами. Аналіз вибухів газу вивчався як якісно, так і кількісно для кращого розуміння першопричин, що створюють небезпечні аварійні ситуації на підставі аналізу дерева відмов (АДВ). Результати. Встановлено, що 11 нещасних випадків привели до 53 смертельних випадків і 35 травм у період з 2010 по 2018 роки у Пакистані. Значна частина причин (4 з 7), що призвели до 5 з 10 нещасних випадків, 49 з 53 смертей та 28 з 35 травм, була пов’язана з вибухом газу, а основні фактори, що викликають вибух – це накопичення газу і його загоряння. Акцентовано увагу на належну якість проектування шахт, регулярний огляд шахт, дотримання пропонованих правил і норм безпеки. Наукова новизна. Метод АДВ було вперше застосовано для розуміння глибинних причин, що викликають вибух газу у вугільних шахтах Пакистану, а його специфікація дозволила виявити ряд важливих ключових факторів, які слід враховувати для зменшення ризику вибуху газу й запобігання викликаних ним аварій. Практична значимість. Розроблено стратегічні заходи, що дозволяють запобігти або зменшити число аварій зі смертельними наслідками (або без них), викликаних вибухом газу. Для цієї мети пропонується, аби в Пакистані були проведені серйозні структурні реформи і перетворення в галузі охорони праці.Цель. Анализ влияния основных факторов, вызывающих взрывы шахтного газа метана на основе составления модели дерева отказов в условиях угольных шахт Пакистана. Методика. Для достижения цели исследования применен эмпирический анализ взрывов газа в угольных шахтах Пакистана на основе данных с 2010 по 2018 годы для определения точного числа аварий со смертельными случаями и травмами. Анализ взрывов газа изучался как качественно, так и количественно для лучшего понимания первопричин, которые создают опасные аварийные ситуации на основании анализа дерева отказов (АДО). Результаты. Установлено, что 11 несчастных случаев привели к 53 смертельным случаям и 35 травмам в период с 2010 по 2018 годы в Пакистане. Значительная часть причин (4 из 7), приведших к 5 из 10 несчастных случаев, 49 из 53 смертей и 28 из 35 травм, была связана со взрывом газа, а основные факторы, вызывающие взрыв – это накопление газа и его возгорание. Акцентировано внимание на надлежащее качество проектирования шахт, регулярный осмотр шахт, соблюдение предлагаемых правил и норм безопасности шахт. Научная новизна. Метод АДО был впервые применен впервые для понимания глубинных причин, вызывающих взрыв газа в угольных шахтах Пакистана, а его спецификация позволила выявить ряд важных ключевых факторов, которые следует учитывать для сокращения риска взрыва газа и предотвращения вызванных им аварий. Практическая значимость. Разработаны стратегические меры, позволяющие предотвратить или уменьшить число аварий со смертельными последствиями (или без них), вызванных взрывом газа. Для этой цели предлагается, чтобы в Пакистане были проведены серьезные структурные реформы и преобразования в области охраны труда.This research was funded by the National Natural Science Foundation of China (51574226) and 2017 Special Project of Subject Frontiers Scientific Research in China University of Mining and Technology (2017XKQY047). Additionally, authors are very thankful to the School of Mines, China University of Mining and Technology, Xuzhou, 221116 China, whose support allowed to accomplish this research within the specified time

Fault tree analysis and prevention strategies for gas explosion in underground coal mines of Pakistan

Purpose. Gas explosion in the underground coal mines of Pakistan is the main source of coal miners’ mortalities. The purpose of this article is to analyze the main causes of gas explosion in the underground coal mines of Pakistan. Methods. The study employs the Fault Tree Analysis (FTA) to understand the key root causes that lead to system failure. Particularly, this research has articulated the fault tree model in case of gas explosion in underground coal mines to analyze the root causes of this dangerous accident. Findings. This analysis has revealed that most of the root causes (4/7) with 5/10 accidents, 49/53 fatalities and 28/35 injuries resulted from primary failure of the gas explosion that poses a major threat to lives of mine workers. Similarly, the accumulation of gases and ignition are leading causes of gas explosion. Originality. FTA has been employed for the first time to understand the underlying root causes with the corresponding number of accident, fatalities and injuries of gas explosion in underground coal mines of Pakistan. This original application of FTA to the problem under discussion presents some important underlying factors which should be considered to reduce the risk of gas explosion and its related fatal and non-fatal accidents. Practical implications. The study proposes preventive strategies to lessen the fatal and non-fatal accidents resulting from gas explosions. Explicitly, Pakistan has to conduct major structural and safety management reforms.Мета. Аналіз впливу основних факторів, що викликають вибухи шахтного газу метану, на основі складання моделі дерева відмов в умовах вугільних шахт Пакистану. Методика. Для досягнення мети дослідження застосовано емпіричний аналіз вибухів газу у вугільних шахтах Пакистану на основі даних з 2010 по 2018 роки для визначення точного числа аварій зі смертельними випадками і травмами. Аналіз вибухів газу вивчався як якісно, так і кількісно для кращого розуміння першопричин, що створюють небезпечні аварійні ситуації на підставі аналізу дерева відмов (АДВ). Результати. Встановлено, що 11 нещасних випадків привели до 53 смертельних випадків і 35 травм у період з 2010 по 2018 роки у Пакистані. Значна частина причин (4 з 7), що призвели до 5 з 10 нещасних випадків, 49 з 53 смертей та 28 з 35 травм, була пов’язана з вибухом газу, а основні фактори, що викликають вибух – це накопичення газу і його загоряння. Акцентовано увагу на належну якість проектування шахт, регулярний огляд шахт, дотримання пропонованих правил і норм безпеки. Наукова новизна. Метод АДВ було вперше застосовано для розуміння глибинних причин, що викликають вибух газу у вугільних шахтах Пакистану, а його специфікація дозволила виявити ряд важливих ключових факторів, які слід враховувати для зменшення ризику вибуху газу й запобігання викликаних ним аварій. Практична значимість. Розроблено стратегічні заходи, що дозволяють запобігти або зменшити число аварій зі смертельними наслідками (або без них), викликаних вибухом газу. Для цієї мети пропонується, аби в Пакистані були проведені серйозні структурні реформи і перетворення в галузі охорони праці.Цель. Анализ влияния основных факторов, вызывающих взрывы шахтного газа метана на основе составления модели дерева отказов в условиях угольных шахт Пакистана. Методика. Для достижения цели исследования применен эмпирический анализ взрывов газа в угольных шахтах Пакистана на основе данных с 2010 по 2018 годы для определения точного числа аварий со смертельными случаями и травмами. Анализ взрывов газа изучался как качественно, так и количественно для лучшего понимания первопричин, которые создают опасные аварийные ситуации на основании анализа дерева отказов (АДО). Результаты. Установлено, что 11 несчастных случаев привели к 53 смертельным случаям и 35 травмам в период с 2010 по 2018 годы в Пакистане. Значительная часть причин (4 из 7), приведших к 5 из 10 несчастных случаев, 49 из 53 смертей и 28 из 35 травм, была связана со взрывом газа, а основные факторы, вызывающие взрыв – это накопление газа и его возгорание. Акцентировано внимание на надлежащее качество проектирования шахт, регулярный осмотр шахт, соблюдение предлагаемых правил и норм безопасности шахт. Научная новизна. Метод АДО был впервые применен впервые для понимания глубинных причин, вызывающих взрыв газа в угольных шахтах Пакистана, а его спецификация позволила выявить ряд важных ключевых факторов, которые следует учитывать для сокращения риска взрыва газа и предотвращения вызванных им аварий. Практическая значимость. Разработаны стратегические меры, позволяющие предотвратить или уменьшить число аварий со смертельными последствиями (или без них), вызванных взрывом газа. Для этой цели предлагается, чтобы в Пакистане были проведены серьезные структурные реформы и преобразования в области охраны труда.This research was funded by the National Natural Science Foundation of China (51574226) and 2017 Special Project of Subject Frontiers Scientific Research in China University of Mining and Technology (2017XKQY047). Additionally, authors are very thankful to the School of Mines, China University of Mining and Technology, Xuzhou, 221116 China, whose support allowed to accomplish this research within the specified time

Hepatitis B and hepatitis C in Pakistan: prevalence and risk factors

SummaryBackgroundPakistan carries one of the world’s highest burdens of chronic hepatitis and mortality due to liver failure and hepatocellular carcinomas. However, national level estimates of the prevalence of and risk factors for hepatitis B and hepatitis C are currently not available.MethodsWe reviewed the medical and public health literature over a 13-year period (January 1994–September 2007) to estimate the prevalence of active hepatitis B and chronic hepatitis C in Pakistan, analyzing data separately for the general and high-risk populations and for each of the four provinces. We included 84 publications with 139 studies (42 studies had two or more sub-studies).ResultsMethodological differences in studies made it inappropriate to conduct a formal meta-analysis to determine accurate national prevalence estimates, but we estimated the likely range of prevalence in different population sub-groups. A weighted average of hepatitis B antigen prevalence in pediatric populations was 2.4% (range 1.7–5.5%) and for hepatitis C antibody was 2.1% (range 0.4–5.4%). A weighted average of hepatitis B antigen prevalence among healthy adults (blood donors and non-donors) was 2.4% (range 1.4–11.0%) and for hepatitis C antibody was 3.0% (range 0.3–31.9%). Rates in the high-risk subgroups were far higher.ConclusionsData suggest a moderate to high prevalence of hepatitis B and hepatitis C in different areas of Pakistan. The published literature on the modes of transmission of hepatitis B and hepatitis C in Pakistan implicate contaminated needle use in medical care and drug abuse and unsafe blood and blood product transfusion as the major causal factors

Adsorption of endocrine disrupting compounds and other emerging contaminants using lignocellulosic biomass-derived porous carbons: A review

Hydrochars from lignocellulose biomass have received an upsurge of interest in different fields, especially in the area of adsorption. Hydrothermally produced hydrochars are effective adsorbents for removing different pollutants, and they serve as a cheap and sustainable raw material for subsequent activation to achieve porous activated carbons (ACs) with large surface areas. In this review, recent studies on preparation and characteristics of adsorbents in terms of hydrochars from lignocellulose biomass and their derived ACs are presented and discussed. The application of these adsorbents for the removal of endocrine disrupting chemicals and other emerging pollutants is included. The sources and classification, adsorption isotherm, kinetics, and mechanism of these pollutants and the capability of regenerating and reusing cheap and efficient adsorbents such as hydrochar and ACs are also discussed. This review identifies knowledge gaps and proposes insights into new directions for improving the applications of hydrochar and ACs as adsorbents.The publication of this article was funded by the Qatar National Library.Scopu

Residual stress in laser cladded rail

To improve the fatigue life of components subject to loads with high surface strain gradients, it is possible to coat them with an alloy of higher durability. The present study focuses on the effect of cladding high value track components, made of a standard rail steel UIC 900A/grade 260, with a layer of a premium martensitic stainless steel to reduce wear and fatigue. The laser cladding process inevitably generates residual stresses in the clad and parent metal, which could be detrimental to the integrity of the component. Therefore, measurements to determine the residual stress state of cladded rail were performed using semi-destructive centre-hole and deep hole drilling and non-destructive neutron diffraction techniques. Subsequently, the effects of cycling loading and wear, representative of typical service loads, on the redistribution of the residual stress field were investigated. It was observed that laser cladding causes a triaxial compressive residual stress field in the clad and near the interface and a tensile stress field in the parent material. The stress field is shown to change when the first cycle of load is applied but reaches a steady state after only 10 cycles: After the 10th cycle there is no evidence that the clad continues accumulating strain which could indicate that there is low risk of ratcheting. Wear effect on residual stress redistribution was found to be local on the surface of the specimen only

The management of diabetic ketoacidosis in children

The object of this review is to provide the definitions, frequency, risk factors, pathophysiology, diagnostic considerations, and management recommendations for diabetic ketoacidosis (DKA) in children and adolescents, and to convey current knowledge of the causes of permanent disability or mortality from complications of DKA or its management, particularly the most common complication, cerebral edema (CE). DKA frequency at the time of diagnosis of pediatric diabetes is 10%–70%, varying with the availability of healthcare and the incidence of type 1 diabetes (T1D) in the community. Recurrent DKA rates are also dependent on medical services and socioeconomic circumstances. Management should be in centers with experience and where vital signs, neurologic status, and biochemistry can be monitored with sufficient frequency to prevent complications or, in the case of CE, to intervene rapidly with mannitol or hypertonic saline infusion. Fluid infusion should precede insulin administration (0.1 U/kg/h) by 1–2 hours; an initial bolus of 10–20 mL/kg 0.9% saline is followed by 0.45% saline calculated to supply maintenance and replace 5%–10% dehydration. Potassium (K) must be replaced early and sufficiently. Bicarbonate administration is contraindicated. The prevention of DKA at onset of diabetes requires an informed community and high index of suspicion; prevention of recurrent DKA, which is almost always due to insulin omission, necessitates a committed team effort

Biochemical profile and in vitro neuroprotective properties of Carpobrotus edulis L., a medicinal and edible halophyte native to the coast of South Africa

This work reports the nutritional profile and in vitro neuroprotective properties of leaves of Carpobrotus edulis L, a medicinal and edible succulent species native to the coast of South Africa. Biomass was evaluated for proximate composition and for contents in carotenoids, liposoluble pigments and minerals. Hexane, dichloromethane, ethyl acetate and methanol extracts were prepared by Soxhlet extraction from dried biomass and evaluated for in vitro inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), capacity to attenuate hydrogen peroxide (H2O2)-induced injury in the human dopaminergic cell line SH-SY5Y and for anti-neuroinflammatory potential on lipopolysaccharide (LPS)-stimulated microglia cells. Extracts were evaluated for antioxidant activity by four complementary methods, total content of phenolics, tannins and flavonoids. Finally the profile of the main phenolic compounds was determined by high performance liquid chromatography with diode array detection (HPLC-DAD). C edulis has a high moisture content, high levels of crude protein, fibre, ash, carotenoids, calcium and iron and a low fat level. The extracts were able to efficiently scavenge the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), reduce iron and chelate copper and iron ions, and exhibited different levels of phenolic compounds in the order ethyl acetate > methanol > dichloromethane > hexane. The main compounds detected were gallic and salicylic acids and quercetin, all in the ethyl acetate extract. The extracts allowed a dual and potent inhibition of AChE and BuChE. The dichloromethane and methanol extracts had the strongest capacity to prevent cell death induced by H2O2, and the methanol extract had anti-neuronflammatory properties. All together our results suggest that consumption of leaves of C edulis can contribute for a balanced diet, and that they may add to the improvement of cognitive functions. It also suggests possible novel biotechnological applications of C. edulis such as source of molecules and/or products for the food and/or pharmaceutical industries. Studies aiming to the isolation and identification of the bioactive compounds are already in progress. (C) 2017 SAAB. Published by Elsevier B.V. All rights reserved.Portuguese National BudgetXtremeGourmet project [ALG-01-0247-FEDER-017676]FCT Investigator Programme [IF/00049/2012]info:eu-repo/semantics/publishedVersio

Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations

Solid organ transplant (SOT) recipients are especially at risk of developing infections by multidrug resistant (MDR) Gram-negative bacilli (GNB), as they are frequently exposed to antibiotics and the healthcare setting, and are regulary subject to invasive procedures. Nevertheless, no recommendations concerning prevention and treatment are available. A panel of experts revised the available evidence; this document summarizes their recommendations: (1) it is important to characterize the isolate´s phenotypic and genotypic resistance profile; (2) overall, donor colonization should not constitute a contraindication to transplantation, although active infected kidney and lung grafts should be avoided; (3) recipient colonization is associated with an increased risk of infection, but is not a contraindication to transplantation; (4) different surgical prophylaxis regimens are not recommended for patients colonized with carbapenem-resistant GNB; (5) timely detection of carriers, contact isolation precautions, hand hygiene compliance and antibiotic control policies are important preventive measures; (6) there is not sufficient data to recommend intestinal decolonization; (7) colonized lung transplant recipients could benefit from prophylactic inhaled antibiotics, specially for Pseudomonas aeruginosa; (8) colonized SOT recipients should receive an empirical treatment which includes active antibiotics, and directed therapy should be adjusted according to susceptibility study results and the severity of the infection.J.T.S. holds a research contract from the Fundación para la Formación e Investigación de los Profesionales de la Salud de Extremadura (FundeSalud), Instituto de Salud Carlos III. M.F.R. holds a clinical research contract “Juan Rodés” (JR14/00036) from the Spanish Ministry of Economy and Competitiveness, Instituto de Salud Carlos III

Search for H→γγ produced in association with top quarks and constraints on the Yukawa coupling between the top quark and the Higgs boson using data taken at 7 TeV and 8 TeV with the ATLAS detector

A search is performed for Higgs bosons produced in association with top quarks using the diphoton decay mode of the Higgs boson. Selection requirements are optimized separately for leptonic and fully hadronic final states from the top quark decays. The dataset used corresponds to an integrated luminosity of 4.5 fb−14.5 fb−1 of proton–proton collisions at a center-of-mass energy of 7 TeV and 20.3 fb−1 at 8 TeV recorded by the ATLAS detector at the CERN Large Hadron Collider. No significant excess over the background prediction is observed and upper limits are set on the tt¯H production cross section. The observed exclusion upper limit at 95% confidence level is 6.7 times the predicted Standard Model cross section value. In addition, limits are set on the strength of the Yukawa coupling between the top quark and the Higgs boson, taking into account the dependence of the tt¯H and tH cross sections as well as the H→γγ branching fraction on the Yukawa coupling. Lower and upper limits at 95% confidence level are set at −1.3 and +8.0 times the Yukawa coupling strength in the Standard Model