Validity of an Artificial Neural Network in the Diagnosis of COPD

Background/Purpose: Neur al net wor ks anal yze a l arge amount of information and are useful in the classification of patients for the diagnosis of chronic obstructive pulmonary disease (COPD). However, its comparative performance with questionnaires for the diagnosis of COPD is unknown. The objective of the study is to evaluate the performance of a neural network against clinical questionnaires in the diagnosis of COPD. Methods: A cross-sectional study was carried out applying the clinical questionnaires and a perceptron neural network against the spirometric diagnosis of COPD. Results: A total of 1590 patients were admitted to the study, 13.5% of them were confirmed for COPD diagnosis. In the general population, average age was 67.6 years (SD = 14.0), and smoking history was 47.7% (758/1590). The questionnaire with the highest performance was the Could it be COPD with an ACOR of 0.83 (95% CI, 0.81–0.86) (p < 0.001), and the lowest performance was the LFQ with an ACOR of 0.66. (95% CI, 0.62–0.70)(p < 0.001). The ANNs showed an ACOR of 0.89 (95% CI, 0.86–0.91) (p < 0.001). Conclusion: Neural networks show a better diagnostic performance than the usual clinical questionnaires for the diagnosis of COPD. © 2024, Full Universe Integrated Marketing Limited. All rights reserved

Validez del exceso de bases como factor pronóstico de mortalidad en pacientes traumatizados

5 páginasBackground: Base excess is used to determine the mag-nitude of metabolic abnormality secondary to hemorrhage or direct organ damage of patients with polytrauma Objective: To determine what are the values of change that BE can have over time and that allow predicting early mortality in patients with polytrauma. Methods: Retrospective cohort study in subjects older than 18 years, who were admitted to the intensive care unit for any type of trauma. The response to the change of the base excess at 6, 12 and 24 hours after the trauma was evaluated. Results: 261 subjects were included, 22.6% (59/261) died. Polytrauma occurred in 73.2% (191/261) and traf-fic accident was the most common mechanism of trauma in the study population with 75.9%. The change in BE between admission and the first 6 hours was 1.7 mEq/L (SD: 4.02) in the living population and 1.9 mEq/L (SD: 8.1) in the deceased (p<0.001). The change in mEq/L between admission and first 6 hours showed a low receiver operat-ing characteristics curve area of 0.661 (95% CI: 0.523-0.8; p=0.025). Conclusión: The change in base excess between the first 6 to 12 hours after patient admission can be used to esti-mate mortality in patients diagnosed with trauma. © 2023, Venezuelan Society of Pharmacology and Clinical and Therapeutic Pharmacology. All rights reserved