Photosynthesis and growth reduction with warming are driven by nonstomatal limitations in a Mediterranean semi-arid shrub

Whereas warming enhances plant nutrient status and photosynthesis in most terrestrial ecosystems, dryland vegetation is vulnerable to the likely increases in evapotranspiration and reductions in soil moisture caused by elevated temperatures. Any warming‐induced declines in plant primary production and cover in drylands would increase erosion, land degradation, and desertification. We conducted a four‐year manipulative experiment in a semi‐arid Mediterranean ecosystem to evaluate the impacts of a ~2°C warming on the photosynthesis, transpiration, leaf nutrient status, chlorophyll content, isotopic composition, biomass growth, and postsummer survival of the native shrub Helianthemum squamatum. We predicted that warmed plants would show reduced photosynthetic activity and growth, primarily due to the greater stomatal limitation imposed by faster and more severe soil drying under warming. On average, warming reduced net photosynthetic rates by 36% across the study period. Despite this strong response, warming did not affect stomatal conductance and transpiration. The reduction of peak photosynthetic rates with warming was more pronounced in a drought year than in years with near‐average rainfall (75% and 25–40% reductions relative to controls, respectively), with no indications of photosynthetic acclimation to warming through time. Warmed plants had lower leaf N and P contents, δ (13)C, and sparser and smaller leaves than control plants. Warming reduced shoot dry mass production by 31%. However, warmed plants were able to cope with large reductions in net photosynthesis, leaf area, and shoot biomass production without changes in postsummer survival rates. Our findings highlight the key role of nonstomatal factors (biochemical and/or nutritional) in reducing net carbon assimilation rates and growth under warming, which has important implications for projections of plant carbon balance under the warmer and drier climatic scenario predicted for drylands worldwide. Projected climate warming over the coming decades could reduce net primary production by about one‐third in semi‐arid gypsum shrublands dominated by H. squamatum

Plant’s gypsum affinity shapes responses to specific edaphic constraints without limiting responses to other general constraints

Aims: Harsh edaphic environments harbor species with different soil affinities. Plant’s responses to specific edaphic constraints may be compromised against responses to prevalent stresses shared with other semi-arid environments. We expect that species with high edaphic affinity may show traits to overcome harsh soil properties, while species with low affinity may respond to environmental constraints shared with arid environments. Methods: We quantified the edaphic affinity of 12 plant species co-occurring in gypsum outcrops and measured traits related to plant responses to specific gypsum constraints (rooting and water uptake depth, foliar accumulation of Ca, S and Mg), and traits related to common constraints of arid environments (water use efficiency, macronutrients foliar content). Results: Plants in gypsum outcrops differed in their strategies to face edaphic limitations. A phylogenetic informed PCA segregated species based on their foliar Ca and S accumulation and greater water uptake depths, associated with plant responses to specific gypsum limitations. Species’ gypsum affinity explained this segregation, but traits related to water or nutrient use efficiency did not contribute substantially to this axis. Conclusions: Plant’s specializations to respond to specific edaphic constraints of gypsum soils do not limit their ability to deal with other non-specific environmental constraints

Apoptosis in hypertensive heart disease: a clinical approach

PURPOSE OF REVIEW: It is widely accepted that there are two principal forms of cell death, namely, necrosis and apoptosis. According to the classical view, necrosis is the major mechanism of cardiomyocyte death in cardiac diseases. RECENT DEVELOPMENTS: In the past few years observations have been made showing that cardiomyocyte apoptosis occurs in diverse conditions including hypertensive heart disease, and that apoptosis may be a contributing cause of loss and functional abnormalities of cardiomyocytes in this condition. SUMMARY: This review will summarize recent evidence demonstrating the potential contribution of cardiomyocyte apoptosis to heart failure in hypertensive patients. In addition, some strategies aimed to detect and prevent apoptosis of cardiomyocytes will be considered

Recommended care for young people (15-19 years) after suicide attempts in certain European countries

Abstract Data on recommended care for young people aged 15±19 years after attempted suicide from nine European research centres dur- ing the period 1989±1992 were ana- lysed in terms of gender, history of previous suicide attempt and meth- ods used. Altogether 438 suicide attempts made by 353 boys and 1,102 suicide attempts made by 941 girls were included. Analyses of the total data from all centres showed that young people with a history of previous suicide attempt and those using violent methods had signi®- cantly higher chance of being rec- ommended aftercare than ®rst-time attempters or those choosing self- poisoning. There were no signi®cant di erences of being recommended care between genders. Logistic re- gression analyses of the material were performed and the results were similar. Both having previous at- tempted suicide (odds ratio 2.0, 95% CI 1.53±2.61) and using ``hard'' methods (odds ratio 1.71, 95% CI 1.49±1.96) were signi®cantly associ- ated with increased possibility of being recommended aftercare. When individual centres were analysed, large disparities of recommended care after suicide attempts were found and there were no uniform criteria of recommending care for young suicide attempters in Europe. Key words Young people ± attempted suicide ± method ± recommended car

DustPedia: Multiwavelength photometry and imagery of 875 nearby galaxies in 42 ultraviolet-microwave bands

Aims. The DustPedia project is capitalising on the legacy of the Herschel Space Observatory, using cutting-edge modelling techniques to study dust in the 875 DustPedia galaxies – representing the vast majority of extended galaxies within 3000 km s-1 that were observed by Herschel. This work requires a database of multiwavelength imagery and photometry that greatly exceeds the scope (in terms of wavelength coverage and number of galaxies) of any previous local-Universe survey. Methods. We constructed a database containing our own custom Herschel reductions, along with standardised archival observations from GALEX, SDSS, DSS, 2MASS, WISE, Spitzer, and Planck. Using these data, we performed consistent aperture-matched photometry, which we combined with external supplementary photometry from IRAS and Planck. Results. We present our multiwavelength imagery and photometry across 42 UV-microwave bands for the 875 DustPedia galaxies. Our aperture-matched photometry, combined with the external supplementary photometry, represents a total of 21 857 photometric measurements. A typical DustPedia galaxy has multiwavelength photometry spanning 25 bands. We also present the Comprehensive & Adaptable Aperture Photometry Routine (CAAPR), the pipeline we developed to carry out our aperture-matched photometry. CAAPR is designed to produce consistent photometry for the enormous range of galaxy and observation types in our data. In particular, CAAPR is able to determine robust cross-compatible uncertainties, thanks to a novel method for reliably extrapolating the aperture noise for observations that cover a very limited amount of background. Our rich database of imagery and photometry is being made available to the community

Resolved stellar population properties of PHANGS-MUSE galaxies

Analyzing resolved stellar populations across the disk of a galaxy can provide unique insights into how that galaxy assembled its stellar mass over its lifetime. Previous work at ~1 kpc resolution has already revealed common features in the mass buildup (e.g., inside-out growth of galaxies). However, even at approximate kpc scales, the stellar populations are blurred between the different galactic morphological structures such as spiral arms, bars and bulges. Here we present a detailed analysis of the spatially resolved star formation histories (SFHs) of 19 PHANGS-MUSE galaxies, at a spatial resolution of ~100 pc. We show that our sample of local galaxies exhibits predominantly negative radial gradients of stellar age and [Z/H], consistent with previous findings, and a radial structure that is primarily consistent with local star formation, and indicative of inside-out formation. In barred galaxies, we find flatter [Z/H] gradients along the semi-major axis of the bar than along the semi-minor axis, as is expected from the radial mixing of material along the bar. In general, the derived assembly histories of the galaxies in our sample tell a consistent story of inside-out growth, where low-mass galaxies assembled the majority of their stellar mass later in cosmic history than high-mass galaxies. We also show how stellar populations of different ages exhibit different kinematics, with younger stellar populations having lower velocity dispersions than older stellar populations at similar galactocentric distances, which we interpret as an imprint of the progressive dynamical heating of stellar populations as they age. Finally, we explore how the time-averaged star formation rate evolves with time, and how it varies across galactic disks. This analysis reveals a wide variation of the SFHs of galaxy centers and additionally shows that structural features become less pronounced with age.Comment: 52 pages, 48 figures, accepted for publication in A&

Stellar populations of bulges at low redshift

This chapter summarizes our current understanding of the stellar population properties of bulges and outlines important future research directions.Comment: Review article to appear in "Galactic Bulges", Editors: Laurikainen E., Peletier R., Gadotti D., Springer Publishing. 34 pages, 12 figure

Diagnostic value of cerebrospinal fluid alpha-synuclein seed quantification in synucleinopathies

Several studies have confirmed the α-synuclein real-time quaking-induced conversion (RT-QuIC) assay to have high sensitivity and specificity for Parkinson's disease. However, whether the assay can be used as a robust, quantitative measure to monitor disease progression, stratify different synucleinopathies and predict disease conversion in patients with idiopathic REM sleep behaviour disorder remains undetermined. The aim of this study was to assess the diagnostic value of CSF α-synuclein RT-QuIC quantitative parameters in regard to disease progression, stratification and conversion in synucleinopathies. We performed α-synuclein RT-QuIC in the CSF samples from 74 Parkinson's disease, 24 multiple system atrophy and 45 idiopathic REM sleep behaviour disorder patients alongside 55 healthy controls, analysing quantitative assay parameters in relation to clinical data. α-Synuclein RT-QuIC showed 89% sensitivity and 96% specificity for Parkinson's disease. There was no correlation between RT-QuIC quantitative parameters and Parkinson's disease clinical scores (e.g. Unified Parkinson's Disease Rating Scale motor), but RT-QuIC positivity and some quantitative parameters (e.g. Vmax) differed across the different phenotype clusters. RT-QuIC parameters also added value alongside standard clinical data in diagnosing Parkinson's disease. The sensitivity in multiple system atrophy was 75%, and CSF samples showed longer T50 and lower Vmax compared to Parkinson's disease. All RT-QuIC parameters correlated with worse clinical progression of multiple system atrophy (e.g. change in Unified Multiple System Atrophy Rating Scale). The overall sensitivity in idiopathic REM sleep behaviour disorder was 64%. In three of the four longitudinally followed idiopathic REM sleep behaviour disorder cohorts, we found around 90% sensitivity, but in one sample (DeNoPa) diagnosing idiopathic REM sleep behaviour disorder earlier from the community cases, this was much lower at 39%. During follow-up, 14 of 45 (31%) idiopathic REM sleep behaviour disorder patients converted to synucleinopathy with 9/14 (64%) of convertors showing baseline RT-QuIC positivity. In summary, our results showed that α-synuclein RT-QuIC adds value in diagnosing Parkinson's disease and may provide a way to distinguish variations within Parkinson's disease phenotype. However, the quantitative parameters did not correlate with disease severity in Parkinson's disease. The assay distinguished multiple system atrophy patients from Parkinson's disease patients and in contrast to Parkinson's disease, the quantitative parameters correlated with disease progression of multiple system atrophy. Our results also provided further evidence for α-synuclein RT-QuIC having potential as an early biomarker detecting synucleinopathy in idiopathic REM sleep behaviour disorder patients prior to conversion. Further analysis of longitudinally followed idiopathic REM sleep behaviour disorder patients is needed to better understand the relationship between α-synuclein RT-QuIC signature and the progression from prodromal to different synucleinopathies

Sub-kiloparsec empirical relations and excitation conditions of HCN and HCO+ J=3-2 in nearby star-forming galaxies

We present new HCN and HCO+ (J = 3–2) images of the nearby star-forming galaxies (SFGs) NGC 3351, NGC 3627, and NGC 4321. The observations, obtained with the Morita ALMA Compact Array, have a spatial resolution of ∼290–440 pc and resolve the inner Rgal ≲ 0.6–1 kpc of the targets, as well as the southern bar end of NGC 3627. We complement this data set with publicly available images of lower excitation lines of HCN, HCO+, and CO and analyse the behaviour of a representative set of line ratios: HCN(3–2)/HCN(1–0), HCN(3–2)/HCO+(3–2), HCN(1–0)/CO(2–1), and HCN(3–2)/CO(2–1). Most of these ratios peak at the galaxy centres and decrease outwards. We compare the HCN and HCO+ observations with a grid of one-phase, non-local thermodynamic equilibrium (non-LTE) radiative transfer models and find them compatible with models that predict subthermally excited and optically thick lines. We study the systematic variations of the line ratios across the targets as a function of the stellar surface density (Σstar), the intensity-weighted CO(2–1) (⟨ICO⟩), and the star formation rate surface density (ΣSFR). We find no apparent correlation with ΣSFR, but positive correlations with the other two parameters, which are stronger in the case of ⟨ICO⟩. The HCN/CO–⟨ICO⟩ relations show ≲0.3 dex galaxy-to-galaxy offsets, with HCN(3–2)/CO(2–1)–⟨ICO⟩ being ∼2 times steeper than HCN(1–0)/CO(2–1). In contrast, the HCN(3–2)/HCN(1–0)–⟨ICO⟩ relation exhibits a tighter alignment between galaxies. We conclude that the overall behaviour of the line ratios cannot be ascribed to variations in a single excitation parameter (e.g., density or temperature)