335 research outputs found
POINT CLOUD EXPLOITATION FOR STRUCTURAL MODELING AND ANALYSIS: A RELIABLE WORKFLOW
none4noThe digitization and geometric knowledge of the historical built heritage is currently based on point cloud, that rarely or only partially is used as digital twin for structural analysis. The present work deals with historical artefacts survey, with particular reference to masonry structures, aimed to their structural analysis and assessment. In detail, the study proposes a methodology capable of employing semi-directly the original data obtained from the 3D digital survey for the generation of a Finite Element Model (FEM), used for structural analysis of masonry buildings.
The methodology described presents a reliable workflow with twofold purpose: the improvement of the transformation process of the point cloud in solid and subsequently obtain a high-quality and detailed model for structural analyses.
Through the application of the methodology to a case study, the method consistency was assessed, regarding the smoothness of the whole procedure and the dynamic characterization of the Finite Element Model. The main improvement in respect with similar or our previous workflows is obtained by the introduction of the retopology in data processing, allowing the transformation of the raw data into a solid model with optimal balancing between Level of Detail (LOD) and computational weight. Another significant aspect of the optimized process is undoubtedly the possibility of faithfully respecting the semantics of the structure, leading to the discretization of the model into different parts depending on the materials. This work may represent an excellent reference for the study of masonry artefacts belonging to the existing historical heritage, starting from surveys and with the purpose to structural and seismic evaluations, in the general framework of knowledge-based preservation of heritage.openLucidi, A.; Giordano, E.; Clementi, F.; Quattrini, R.Lucidi, A.; Giordano, E.; Clementi, F.; Quattrini, R
On the Thermodynamic Bethe Ansatz Equation in Sinh-Gordon Model
Two implicit periodic structures in the solution of sinh-Gordon thermodynamic
Bethe ansatz equation are considered. The analytic structure of the solution as
a function of complex is studied to some extent both analytically and
numerically. The results make a hint how the CFT integrable structures can be
relevant in the sinh-Gordon and staircase models. More motivations are figured
out for subsequent studies of the massless sinh-Gordon (i.e. Liouville) TBA
equation.Comment: 32 pages, 18 figures, myart.st
Integrated Care for Chronic Diseases – State of the Art
Chronic diseases represent a high cost for healthcare systems, for individuals, families, businesses and governments. The World Health Organization (WHO) estimates that an increase of 10% of chronic diseases is associated with a reduction of 0.5% of annual economic growth. Primary care has proven to ensure high levels of efficiency, effectiveness, equity, safety, timely and centrality of the patient achieving better health outcomes and lower costs. The Chronic Care Model (CCM) proposes a proactive approach in assisting the empowerment of patients and their community. The CCM contributes to improving the quality of care and health outcomes and the reduction of inequalities (e.g., ethnicity, social status) too
Infrared Behaviour of Massless Integrable Flows entering the Minimal Models from phi_31
It is known that any minimal model M_p receives along its phi_31 irrelevant
direction *two* massless integrable flows: one from M_{p+1} perturbed by
phi_{13}, the other from Z_{p-1} parafermionic model perturbed by its
generating parafermion field. By comparing Thermodynamic Bethe Ansatz data and
``predictions'' of infrared Conformal Perturbation Theory we show that these
two flows are received by M_p with opposite coupling constants of the phi_31
irrelevant perturbation. Some comments on the massless S matrices of these two
flows are added.Comment: 12 pages, Latex - One misprinted (uninfluent) coefficient corrected
in Tab.
Ce-exchange capacity of zeolite L in different cationic forms: a structural investigation
Cerium exchange by microporous materials, such as zeolites, has important applications in different fields, for example, rare earth element recovery from waste or catalytic processes. This work investigated the Ce-exchange capacity of zeolite L in three different cationic forms (the as-synthesized K form and Naand NH4-exchanged ones) from a highly concentrated solution. Chemical analyses and structural investigations allowed determination of the mechanisms involved in the exchanges and give new insights into the interactions occurring between the cations and the zeolite framework. Different cation sites are involved: (i) K present in the original LTL in the cancrinite cage (site KB) cannot be exchanged; (ii) the cations in KD (in the 12-membered ring channel) are always exchanged; while (iii) site KC (in the eight-membered ring channel) is involved only when K+ is substituted by NH4+, thus promoting a higher exchange rate for NH4+ -> K+ than for Na+ -> K+. In the Ce-exchanged samples, a new site occupied by Ce appears in the centre of the main channel, accompanied by an increase in the number of and a rearrangement of H2O molecules. In terms of Ce exchange, the three cationic forms behave similarly, from both the chemical and structural point of view (exchanged Ce ranges from 38 to 42% of the pristine cation amount). Beyond the intrinsic structural properties of the zeolite L framework, the Ce exchange seems thus also governed by the water coordination sphere of the cation. Complete Ce recovery from zeolite pores was achieved
Excited State Destri - De Vega Equation for Sine-Gordon and Restricted Sine-Gordon Models
We derive a generalization of the Destri - De Vega equation governing the
scaling functions of some excited states in the Sine-Gordon theory. In
particular configurations with an even number of holes and no strings are
analyzed and their UV limits found to match some of the conformal dimensions of
the corresponding compactified massless free boson. Quantum group reduction
allows to interpret some of our results as scaling functions of excited states
of Restricted Sine-Gordon theory, i.e. minimal models perturbed by phi_13 in
their massive regime. In particular we are able to reconstruct the scaling
functions of the off-critical deformations of all the scalar primary states on
the diagonal of the Kac-table.Comment: Latex, 12 page
Nonlinear integral equations for finite volume excited state energies of the O(3) and O(4) nonlinear sigma-models
We propose nonlinear integral equations for the finite volume one-particle
energies in the O(3) and O(4) nonlinear sigma-models. The equations are written
in terms of a finite number of components and are therefore easier to solve
numerically than the infinite component excited state TBA equations proposed
earlier. Results of numerical calculations based on the nonlinear integral
equations and the excited state TBA equations agree within numerical precision.Comment: numerical results adde
Aldehyde dehydrogenases and prostate cancer: Shedding light on isoform distribution to reveal druggable target
Prostate cancer represents the most common malignancy diagnosed in men, and is the second-leading cause of cancer death in this population. In spite of dedicated efforts, the current therapies are rarely curative, requiring the development of novel approaches based on innovative molecular targets. In this work, we validated aldehyde dehydrogenase 1A1 and 1A3 isoform expressions in different prostatic tissue-derived cell lines (normal, benign and malignant) and patient-derived primary prostate tumor epithelial cells, demonstrating their potential for therapeutic intervention using a small library of aldehyde dehydrogenase inhibitors. Compound 3b, 6-(4-fluorophenyl)-2-phenylimidazo [1,2-a]pyridine exhibited not only antiproliferative activity in the nanomolar range against the P4E6 cell line, derived from localized prostate cancer, and PC3 cell lines, derived from prostate cancer bone metastasis, but also inhibitory efficacy against PC3 colony-forming efficiency. Considering its concomitant reduced activity against normal prostate cells, 3b has the potential as a lead compound to treat prostate cancer by means of a still untapped molecular target
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