15 research outputs found
High Expression of Cancer-Derived Glycosylated Immunoglobulin G Predicts Poor Prognosis in Pancreatic Ductal Adenocarcinoma: Erratum.
[This corrects the article DOI: 10.7150/jca.39800.]
High Expression of Cancer-Derived Glycosylated Immunoglobulin G Predicts Poor Prognosis in Pancreatic Ductal Adenocarcinoma.
Background: Cancer-derived immunoglobulin G (CIgG) has been detected in various cancers and plays important roles in carcinogenesis. The present study aimed to investigate its clinical significance in pancreatic ductal adenocarcinoma (PDAC). Methods: Using tissue microarrays (TMAs) and immunohistochemistry, we assessed CIgG expression in 326 patients who underwent surgical resection for PDAC. The associations between CIgG expression and clinicopathological features and clinical outcomes were analyzed. Functional experiments were also performed to investigate the effect of CIgG on PDAC cells. Results: High CIgG expression was related to poor tumor differentiation and metastasis during follow-up and was associated with poor disease-free survival (DFS) and overall survival (OS). A multivariate Cox regression analysis identified high CIgG expression as an independent prognostic factor for DFS and OS. The incorporation of CIgG expression improved the accuracy of an established prognosis prediction model for 1-year OS and 2-year OS. In vitro studies showed that knocking down CIgG profoundly suppressed the proliferation, migration, and invasion capacity of PDAC cells. Conclusions: CIgG contributes to the malignant behaviors of PDAC and offers a powerful prognostic predictor for these patients
An Analysis of the Artistic Characteristics of Dances in Dunhuang Murals
Dunhuang art is regarded as a great miracle and treasure in the traditional culture and art of the Chinese nation, with the murals in Dunhuang Mogao Grottoes as the main component. Dunhuang dance is not only one of the important components of Dunhuang murals but also embodies rich content and various expressive techniques. In the long process of development, it gradually formed a unique style. Based on this, taking Dunhuang dance as the research object and combining it with the existing research results, this paper aims to explore the performance techniques and characteristics of Dunhuang dance patterns in China's ancient dance from two perspectives, including its style and characteristics, as well as its artistic characteristics in the dance images of Dunhuang murals, and to ponder over how to inject valuable new vitality into the precious heritage left by ancestors
The Effects of Worry, Risk Perception, Information Seeking Experience, and Trust in Misinformation on COVID-19 Fact-Checking: A Survey Study in China
10.1080/17544750.2022.2121931Chinese Journal of Communication162132-14
Tumor-Associated Macrophages Protect Pancreatic Cancer from Complement-Dependent Cytotoxicity by Up-Regulation of Complement Regulator CD59 via IL-6R/STAT3 Signaling Pathway
Tumor Associated Macrophages Protect Pancreatic Cancer from Complement Dependent Cytotoxicity by Up-regulation of Complement Regulator CD59 via IL-6R/STAT3 Signaling Pathway
Multiple Tumor-Associated MicroRNAs Modulate the Survival and Longevity of Dendritic Cells by Targeting YWHAZ and Bcl2 Signaling Pathways
Both miR-17-5p and miR-20a Alleviate Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating STAT3 Expression
High-Performance PdNi Nanoalloy Catalyst in Situ Structured on Ni Foam for Catalytic Deoxygenation of Coalbed Methane: Experimental and DFT Studies
A Ni-foam-structured
PdNi nanoalloy catalyst engineered from nano-
to macro-scales has been successfully fabricated for the catalytic
deoxygenation of coalbed methane (CBM). The catalyst was obtainable
by embedment of Pd nanoparticles onto Ni-foam substrate via a galvanic
exchange reaction method and subsequent in situ activation in the
reaction, which was active at low temperature, selective (no CO formation),
and oscillation free in this CH<sub>4</sub>-rich catalytic combustion
process. Special Pd@NiO (Pd nanoparticles partially wrapped by tiny
NiO fragments) ensembles were formed in the galvanic deposition stage
and could merely be transformed into PdNi nanoalloys in the real reaction
stream at elevated temperatures (e.g., 450 °C or higher). Density
functional theory (DFT) calculations were carried out to reveal the
role of Ni decoration at Pd in PdNi nanoalloy catalyst for the CBM
deoxygenation. By nature, the Pd–Ni alloying modified the electronic
structure of surface Pd and led to a decrease in the O adsorption
energy, which can be taken as the activity descriptor for the CBM
deoxygenation. A reaction kinetic study indicated that the Ni decoration
at Pd by Pd–Ni alloying lowered the apparent activation energy
in comparison to the pristine Pd catalyst, while leading to an increase
of the reaction order of O<sub>2</sub> from −0.6 at Pd catalyst
to −0.3. The foam-structured PdNi nanoalloy catalyst thus offered
enhanced low-temperature activity and the elimination of oscillating
phenomena as the result of a transient balance obtained between the
cycles of O<sub>2</sub> adsorption/activation and CH<sub>4</sub> oxidation