72 research outputs found
ARM-Cortex M3-Based Two-Wheel Robot for Assessing Grid Cell Model of Medial Entorhinal Cortex: Progress towards Building Robots with Biologically Inspired Navigation-Cognitive Maps
This article presents the implementation and use of a two-wheel autonomous robot and its effectiveness as a tool for studying the recently discovered use of grid cells as part of mammalianâs brains space-mapping circuitry (specifically the medial entorhinal cortex). A proposed discrete-time algorithm that emulates the medial entorhinal cortex is programed into the robot. The robot freely explores a limited laboratory area in the manner of a rat or mouse and reports information to a PC, thus enabling research without the use of live individuals. Position coordinate neural maps are achieved as mathematically predicted although for a reduced number of implemented neurons (i.e., 200 neurons). However, this type of computational embedded system (robotâs microcontroller) is found to be insufficient for simulating huge numbers of neurons in real time (as in the medial entorhinal cortex). It is considered that the results of this work provide an insight into achieving an enhanced embedded systems design for emulating and understanding mathematical neural network models to be used as biologically inspired navigation system for robots
Self-attraction effect and correction on three absolute gravimeters
The perturbations of the gravitational field due to the mass distribution of
an absolute gravimeter have been studied. The so called Self Attraction Effect
(SAE) is crucial for the measurement accuracy, especially for the International
Comparisons, and for the uncertainty budget evaluation. Three instruments have
been analysed: MPG-2, FG5-238 and IMPG-02. The SAE has been calculated using a
numerical method based on FEM simulation. The observed effect has been treated
as an additional vertical gravity gradient. The correction (SAC) to be applied
to the computed g value has been associated with the specific height level,
where the measurement result is typically reported. The magnitude of the
obtained corrections is of order 1E-8 m/s2.Comment: 14 pages, 8 figures, submitted to Metrologi
Performance of translucent optical networks under dynamic traffic and uncertain physical-layer information
This paper investigates the performance of translucent
Optical Transport Networks (OTNs) under different traffic
and knowledge conditions, varying from perfect knowledge to
drifts and uncertainties in the physical-layer parameters. Our
focus is on the regular operation of a translucent OTN, i.e., after
the dimensioning and regenerator placement phase. Our contributions
can be summarized as follows. Based on the computation
of the Personickâs Q factor, we introduce a new methodology for
the assessment of the optical signal quality along a path, and
show its application on a realistic example. We analyze the performance
of both deterministic and predictive RWA techniques
integrating this signal quality factor Q in the lightpath computation
process. Our results confirm the effectiveness of predictive
techniques to deal with the typical drifts and uncertainties in the
physical-layer parameters, in contrast to the superior efficacy of
deterministic approaches in case of perfect knowledge. Conversely
to most previous works, where all wavelengths are assumed
to have the same characteristics, we examine the case
when the network is not perfectly compensated, so the Maximum
Transmission Distance (MTD) of the different wavelength channels
may vary. We show that blocking might increase dramatically
when the MTD of the different wavelength channels is overlooked.Postprint (published version
Diacutaneous fibrolysis versus passive stretching after articular immobilisation : muscle recovery and extracellular matrix remodelling
Introduction
Atrophy and muscle shortening due to articular immobilisation are common problems in musculoskeletal rehabilitation. Muscle stretching mechanical stimuli might be considered as the golden standard procedure to improve muscle flexibility in rehabilitation. Muscle stretching generates mechanotransduction, potentiating specific gene expression and promotes sarcomerogenesis and extracellular matrix remodelling on shortened and atrophied muscles.
Hypothesis
Diacutaneous fibrolysis, like stretching, uses an external force to stress connective and muscle tissues mechanically to treat muscle shortening; thus, it is widely used in clinical practice even if there is no evidence to support it. Considering this subject, we have hypothesised that diacutaneous fibrolysis can generate mechanotransduction, affecting muscle hypertrophy and extracellular matrix remodelling after immobilisation.
Evaluation of hypothesis
We have designed a laboratory experimental study with a sample of 50 rats. The sample was randomly divided into five groups: Control group (n = 10) with nonâimmobilised rats; 3âweek immobilisation group (n = 10); 3âweek immobilisation/3âweek nonâimmobilisation group (n = 10);3âweek immobilisation/3âweek stretching group (n = 10); and 3âweek immobilisation/3âweek diacutaneous fibrolysis group (n = 10). All rats had their left tibiotarsal joint immobilised in maximum plantar flexion with the orthotics for 3 consecutive weeks. After the immobilisation period, the intervention groups received their respective intervention on their left triceps suralis for 3 weeks. Dependent variables of the study were sarcomere analysis, polymerase chain reaction, connective tissue density, collagen birefringence and matrix metalloproteinases. Statistical analysis was performed using analysis of variance and Duncan post hoc test was applied for differences between groups. For all calculations, a 5% (p < 0.05) significance level was established.
Conclusion
If the hypothesis is confirmed, the present study might provide evidence to support the use of this physical therapy resource widely used to treat muscle dysfunctions
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