113 research outputs found
Влияние проникающей радиации на параметры аналоговых компонентов базового матричного кристалла МН2ХА030
Structured arrays and master slice arrays are often used to reduce cost, design and test time for radiation hardened analog integrated circuits. One of such master slice arrays is МН2ХА030, which uses bipolar and junction field-effect transistors. The purpose of this article is to estimate the effect of ionizing radiation on the parameters of the operational amplifier OAmp2 and comparators ADComp1 and ADComp3 created on the МН2ХА030 master slice array. Еhe results of measurements of analog components after exposure to 60Co gamma quanta with an absorbed dose of up to 700 krad and a fast electron fluence of up to 2.9·1015 el./cm2 with an energy of 6 MeV are presented. The OAmp2 operational amplifier provides a satisfactory level of basic static parameters (input current, offset voltage, voltage gain) at a fast electron fluence of up to 3.7·1014 el./cm2 with an energy of 6 MeV. There are a decrease in the voltage gain and an increase in the offset voltage at electron fluence of greater than 1015 el./cm2. The latter can be caused by a decrease in the efficiency of the common-mode signal feedback integrated into operational amplifier with a significant drop in current gain of bipolar transistors. All considered analog components provide a satisfactory level of basic static parameters at a fast electron fluence of up to 3.7·1014 el./cm2 with an energy of 6 MeV and an absorbed dose of 60Co gamma quanta of at least 700 krad. It is assumed that resistance of OAmp2, ADComp1, ADComp3 to the action of 60Co gamma quanta is significantly higher and requires further research. The developed analog components can be used in signal reading devices required in front-end of sensors for space instrumentation and nuclear electronics.Для уменьшения стоимости, времени проектирования и испытаний радиационно-стойких аналоговых интегральных микросхем часто применяют базовые структурные и базовые матричные кристаллы. Одним из таких базовых матричных кристаллов является МН2ХА030, использующий в качестве активных элементов биполярные и полевые транзисторы, управляемые p-n-переходом. Целью статьи является оценка влияния проникающей радиации на статические параметры операционного усилителя OAmp2 и компараторов ADComp1 и ADComp3, изготовленных на базовом матричном кристалле МН2ХА030. Приведены результаты измерений основных параметров аналоговых компонентов после воздействия гамма-квантов 60Co с поглощенной дозой до 700 крад и флюенса быстрых электронов до 2,9·1015 эл./см2 с энергией 6 МэВ. Как следует из результатов измерений, операционный усилитель OAmp2 обеспечивает удовлетворительный уровень основных статических параметров (входной ток, напряжение смещения нуля, коэффициент усиления напряжения) при флюенсе быстрых электронов до 3,7·1014 эл./см2 с энергией 6 МэВ. При флюенсе быстрых электронов больше 1015 эл./см2 происходит спад коэффициента усиления напряжения и рост напряжения смещения нуля. Последнее может быть вызвано уменьшением эффективности встроенной в операционный усилитель обратной связи по синфазному сигналу при значительном спаде коэффициента усиления базового тока биполярных транзисторов. Все изученные аналоговые компоненты обеспечивают удовлетворительный уровень основных статических параметров при флюенсе быстрых электронов до 3,7·1014 эл./см2 с энергией 6 МэВ и поглощенной дозе гамма-квантов 60Co не менее 700 крад. Предполагается, что стойкость OAmp2, ADComp1, ADComp3 к воздействию гамма-квантов 60Co существенно выше и требует дальнейшего изучения. Разработанные аналоговые компоненты могут найти применение в устройствах считывания сигналов, необходимых в аналоговых интерфейсах датчиков космического приборостроения и ядерной электроники
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in or near KCNQ1. 'Credible sets' of the variants most likely to drive each distinct signal mapped predominantly to noncoding sequence, implying that association with T2D is mediated through gene regulation. Credible set variants were enriched for overlap with FOXA2 chromatin immunoprecipitation binding sites in human islet and liver cells, including at MTNR1B, where fine mapping implicated rs10830963 as driving T2D association. We confirmed that the T2D risk allele for this SNP increases FOXA2-bound enhancer activity in islet- and liver-derived cells. We observed allele-specific differences in NEUROD1 binding in islet-derived cells, consistent with evidence that the T2D risk allele increases islet MTNR1B expression. Our study demonstrates how integration of genetic and genomic information can define molecular mechanisms through which variants underlying association signals exert their effects on disease
Design of low-temperature DDOAs on the elements of BiJFet array chip MH2XA030
Brief information about the new BiJFet array chip (AC) MH2XA030 intended for
accelerated creation of analog integrated circuits (IC), which retain their
performance under the influence of penetrating radiation and extremely low
temperatures (up to minus 197°С) is presented. The features of schematic
design of two types of DDOAs (OAmp3, OAmp4) are considered. The
recommendations on the schematic design of the DDOA are developed taking
into account the static characteristics of the field effect and bipolar
transistors of the AC under the influence of low temperatures. The
amplitude-frequency response of the DDOA and the dependence of the noise
voltage on the frequency of Fourier density are given. At a temperature of
-197°С cryogenic amplifiers OAmp3 (OAmp4) are characterized by the following
parameters: the current consumption is less than 500 μA, the input current
is less than 1 fA, the voltage gain is more than 50.000 (200.000), the
offset voltage is less than 200 (60) μV. The results of the circuit
simulation of the instrumentation amplifier based on DDOA OAmp3 are
presented
Evidence for in semi-inclusive decays of -flavored hadrons
International audienceWe present evidence for the exotic charged charmoniumlike state Zc±(3900) decaying to J/ψπ± in semi-inclusive weak decays of b-flavored hadrons. The signal is correlated with a parent J/ψπ+π- system in the invariant-mass range 4.2–4.7 GeV that would include the exotic structure Y(4260). The study is based on 10.4 fb−1 of pp¯ collision data collected by the D0 experiment at the Fermilab Tevatron collider
Measurement of the forward-backward asymmetry in and baryon production in collisions at TeV
We measure the forward-backward asymmetry in the production of and baryons as a function of rapidity in collisions at TeV using fb of data collected with the D0 detector at the Fermilab Tevatron collider. The asymmetry is determined by the preference of or particles to be produced in the direction of the beam protons or antiprotons, respectively. The measured asymmetry integrated over rapidity in the range is
Measurement of the forward-backward asymmetry in the production of mesons in collisions at = 1.96 TeV
We present a measurement of the forward-backward asymmetry in the production of mesons, , using decays in 10.4 of collisions at TeV collected by the D0 experiment during Run II of the Tevatron collider. A non-zero asymmetry would indicate a preference for a particular flavor, i.e., quark or anti-quark, to be produced in the direction of the proton beam. We extract from a maximum likelihood fit to the difference between forward- and backward-produced mesons. We measure an asymmetry consistent with zero: = [0.24 0.41 (stat) 0.19 (syst)]%
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