Nystrom Methods in the RKQ Algorithm for Initial-value Problems

We incorporate explicit Nystrom methods into the RKQ algorithm for stepwise global error control in numerical solutions of initial-value problems. The initial-value problem is transformed into an explicitly second-order problem, so as to be suitable for Nystrom integration. The Nystrom methods used are fourth-order, fifth-order and 10th-order. Two examples demonstrate the effectiveness of the algorithm.Comment: This is an extension of ideas published in J. Math. Res. (open access); see refs [1] and [2

Iranian hospitality : from caravanserai to bazaar to reporting symbolic experience

This paper reports case studies seeking to address one of the great problems of social science: namely, the extent to which is it possible or desirable accurately to report conscious experience (Hulburt & Scwitzgebel 2007). An interpretive ethnographic approach is used to address this problem. Caravanserais and bazaars in Iran have always offered multi-sensual experiences and represented aspects of symbolic interaction, as well as facilitating physical exchange, between travellers and locals. This is true in their origins, in their nineteenth and twentieth century usage, and in their contemporary roles which increasingly include heritage tourism accommodation or heritage retailing. Using two case studies the paper explores the role that hospitality has played and shows that it has been fundamental to their evolution and remains so, particularly for the commercial caravanserais and tea houses which now exist as refurbished heritage accommodation and restaurants

Potential structural materials and design concepts for light airplanes Final report

Potential structural materials and design concepts evaluated for light aircraft application

PLD.08 Influence of the duration of the second stage on the likelihood of obstetric anal sphincter injury: a retrospective cohort study.

To determine if duration of the second stage influences the likelihood of sustaining obstetric anal sphincter injuries (OASIS) in women undergoing spontaneous vaginal delivery.Othe

Complex responses to movement-based disease control: when livestock trading helps

Livestock disease controls are often linked to movements between farms, for example, via quarantine and pre- or post-movement testing. Designing effective controls, therefore, benefits from accurate assessment of herd-to-herd transmission. Household models of human infections make use of R*, the number of groups infected by an initial infected group, which is a metapopulation level analogue of the basic reproduction number R0 that provides a better characterization of disease spread in a metapopulation. However, existing approaches to calculate R* do not account for individual movements between locations which means we lack suitable tools for livestock systems. We address this gap using next-generation matrix approaches to capture movements explicitly and introduce novel tools to calculate R* in any populations coupled by individual movements. We show that depletion of infectives in the source group, which hastens its recovery, is a phenomenon with important implications for design and efficacy of movement-based controls. Underpinning our results is the observation that R* peaks at intermediate livestock movement rates. Consequently, under movement-based controls, infection could be controlled at high movement rates but persist at intermediate rates. Thus, once control schemes are present in a livestock system, a reduction in movements can counterintuitively lead to increased disease prevalence. We illustrate our results using four important livestock diseases (bovine viral diarrhoea, bovine herpes virus, Johne's disease and Escherichia coli O157) that each persist across different movement rate ranges with the consequence that a change in livestock movements could help control one disease, but exacerbate another

Birth season and environmental influences on blood leucocyte and lymphocyte subpopulations in rural Gambian infants.

BACKGROUND: In rural Gambia, birth season predicts infection-related adult mortality, providing evidence that seasonal factors in early life may programme immune development. This study tested whether lymphocyte subpopulations assessed by automated full blood count and flow cytometry in cord blood and at 8, 16 and 52 weeks in rural Gambian infants (N = 138) are affected by birth season (DRY = Jan-Jun, harvest season, few infections; WET = Jul-Dec, hungry season, many infections), birth size or micronutrient status. RESULTS: Geometric mean cord and postnatal counts were higher in births occurring in the WET season with both season of birth and season of sampling effects. Absolute CD3+, CD8+, and CD56+ counts, were higher in WET season births, but absolute CD4+ counts were unaffected and percentage CD4+ counts were therefore lower. CD19+ counts showed no association with birth season but were associated with concurrent plasma zinc status. There were no other associations between subpopulation counts and micronutrient or anthropometric status. CONCLUSION: These results demonstrate a seasonal influence on cell counts with a disproportionate effect on CD8+ and CD56+ relative to CD4+ cells. This seasonal difference was seen in cord blood (indicating an effect in utero) and subsequent samples, and is not explained by nutritional status. These findings are consistent with the hypothesis than an early environmental exposure can programme human immune development