12 research outputs found
Electrical characterisation of horizontal and vertical gate-all-around Si/SiGe nanowires field effect transistors
No full textThis paper report the technological routes used to build horizontal and vertical gate all-around (GAA) Field-Effect Transistors (FETs) using both Si and SiGe NanoWires (NWs). Horizontal Si and SiGe nanowires FETs are characterized in back gate configuration. Vertical devices using Si nanowires (NWs) show good characteristics with an ION/IOFF ratio close to 106 and sub-threshold slope around 145 mV/decade. Finally, vertical SiGe devices also obtained with the same technological process present an ION/IOFF ratio from 103 to 104 but also poor dynamics which can be explained by the high interface traps density
PiezoNEMS: Semiconductor nanowires and heterostructures for sensing and energy harvesting
No full textInternational audienc
PiezoNEMS: How to enhance piezoelectricity and piezoresistance in semiconductor nanowire for sensors and energy devices
No full textInternational audienc
PiezoNEMS: How to enhance piezoelectricity and piezoresistance in semiconductor nanowire for sensors and energy devices
No full textInternational audienc
PiezoNEMS: How to enhance piezoelectricity and piezoresistance in semiconductor nanowire for sensors and energy devices
No full textInternational audienc
Candida bloodstream infections in intensive care units: analysis of the extended prevalence of infection in intensive care unit study
No full textTo provide a global, up-to-date picture of the prevalence, treatment, and outcomes of Candida bloodstream infections in intensive care unit patients and compare Candida with bacterial bloodstream infection.
DESIGN:
A retrospective analysis of the Extended Prevalence of Infection in the ICU Study (EPIC II). Demographic, physiological, infection-related and therapeutic data were collected. Patients were grouped as having Candida, Gram-positive, Gram-negative, and combined Candida/bacterial bloodstream infection. Outcome data were assessed at intensive care unit and hospital discharge.
SETTING:
EPIC II included 1265 intensive care units in 76 countries.
PATIENTS:
Patients in participating intensive care units on study day.
INTERVENTIONS:
None.
MEASUREMENT AND MAIN RESULTS:
Of the 14,414 patients in EPIC II, 99 patients had Candida bloodstream infections for a prevalence of 6.9 per 1000 patients. Sixty-one patients had candidemia alone and 38 patients had combined bloodstream infections. Candida albicans (n = 70) was the predominant species. Primary therapy included monotherapy with fluconazole (n = 39), caspofungin (n = 16), and a polyene-based product (n = 12). Combination therapy was infrequently used (n = 10). Compared with patients with Gram-positive (n = 420) and Gram-negative (n = 264) bloodstream infections, patients with candidemia were more likely to have solid tumors (p < .05) and appeared to have been in an intensive care unit longer (14 days [range, 5-25 days], 8 days [range, 3-20 days], and 10 days [range, 2-23 days], respectively), but this difference was not statistically significant. Severity of illness and organ dysfunction scores were similar between groups. Patients with Candida bloodstream infections, compared with patients with Gram-positive and Gram-negative bloodstream infections, had the greatest crude intensive care unit mortality rates (42.6%, 25.3%, and 29.1%, respectively) and longer intensive care unit lengths of stay (median [interquartile range]) (33 days [18-44], 20 days [9-43], and 21 days [8-46], respectively); however, these differences were not statistically significant.
CONCLUSION:
Candidemia remains a significant problem in intensive care units patients. In the EPIC II population, Candida albicans was the most common organism and fluconazole remained the predominant antifungal agent used. Candida bloodstream infections are associated with high intensive care unit and hospital mortality rates and resource use
