Life-threatening hypophosphataemia secondary to zoledronic acid implementation in a middle-age patient who presented with advanced osteolysis in the course of multiple myeloma

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Obrzęk szpiku u biorców przeszczepu nerki leczonych inhibitorami kalcyneuryny : opis przypadków

Background: Transient acute musculoskeletal pain syndrome occurs predominantly within the first several months after renal transplantation. Its pathogenesis is not well understood. The toxic effect of calcineurin inhibitors or steroids on bone metabolism has been suspected. Almost all reported cases were associated with the use of cyclosporin A. The pain typically involves distal part of lower extremities and arises in the feet, ankles, or knees. Case report: Two cases are presented of renal allograft recipients who developed severe lower-limb pain in the early period after transplantation while receiving calcineurin-inhibitor (cyclosporin A and tacrolimus). Results: We observed typical clinical and radiological symptoms. The final diagnosis was based on MRI scans. Relief from pain was observed during rest and elevation of the affected extremities. Clinical symptoms and MRI abnormalities resolved spontaneously within a few months

Refleksje na tematy pracy autorstwa A. Popow

<p>The reviewed work "Use the financial health of an organization in financial planning enterprise sports industry working case" was written by a student at the University of Economics in Wroclaw. The review verified the correctness of the estimates and the compliance with the formal requirements for the above work.</p

Wykorzystanie oceny zdrowia finansowego podmiotu do planowania finansowego na przykładzie przedsiębiorstwa działającego w branży sportowej

<p>Przedstawiony dokument stanowi oszacowanie finansowej kondycji polskiego przedsiębiorstwa działającego w branży sportowej. Efekt przeprowadzonej analizy stanowi wyliczony Indeks Kondycji Finansowej Zietlow’a (Financial Health Index). Wskaźniki wykorzystane do jego obliczenia informują o płynności, wypłacalności oraz elastyczności finansowej badanej jednostki. Wskaźnik PHI został oszacowany dla lat 2014 i 2015. Dane finansowe wykorzystane w pracy na lata 2014 i 2015 zostały oszacowane na podstawie dotychczasowej działalności finansowej podmiotu.</p

The patient under the influence of alcohol – Discriminated victim or aggressor?

Introduction: Persons under the influence of alcohol are often admitted as patients to hospital emergency departments (EDs) and other hospital wards. Their behaviour usually differs from the socially accepted norms, and, in consequence, these patients receive lower quality medical care, which is counted as discrimination. In this situation however, it is often difficult to define whether patients under the influence of alcohol are victims of discrimination or aggressors. The aim of this research was the identification of the incidences of unequal treatment of drunken patients by medical staff. Method: The research was conducted from January to June 2015 on a group of 206 hospital ED medical staff, as well as other selected hospital wards, at two hospitals in Bydgoszcz. The diagnostic poll method was used, with the research tool being the original poll survey questionnaire. Non-parametric difference significance tests of independent groups were used for statistical analyses. The acquired data was processed with Statistica PL and Microsoft Excel programmes. Results: The occurrence of unequal treatment by medical staff of patients under the influence of alcohol was observed in the performed studies. There is a correlation between medical staff workplace and the prevalence of discrimination against this group of patients. It most frequently takes place in EDs. In the respondents’ opinion, care and treatment of patients under the influence of alcohol is aggravated by their vulgar behaviour. From viewpoint of the medical staff, the existence of a special care institution for intoxicated persons is justified

Analysis of 30-Day Stroke Mortality in a Community-Based Registry in Warsaw, Poland

Between January 1, 1991, and December 31, 1992, in the Upper Mokotow District of Warsaw, Poland (Population 182,285), 462 First-Ever-In-A-Lifetime (FEL) Strokes Were Registered, 12% (55/462) with Parenchymatous Intracerebral Hemorrhages (PICH) and 88% (407/462) with Ischemic Strokes. Confirmation by Either Computed Tomography or Autopsy Was Made in 72.3% of Cases. the overall 30-Day Case Fatality Rate (CFR) for FEL Strokes Was 40% (186/462), 60% for PICH (33/55), and 38% for Ischemic Stroke (153/407). of the 186 Patients Who Died within 30 Days of their FEL Stroke, 49% (91) Underwent Full Autopsy Examination. Fifty-Two Percent of These 91 Patients Were Found to Have Died from Direct Neurological Sequelae, 21% from Cardiac Causes, 17% from Pneumonia, 5.6% from Septicemia, 2.2% from Pulmonary Emboli, and 2.2% from Metastatic Cancer. Despite Our High 30-Day Stroke CFR Compared with Western Europe and North America, Mechanisms of Death Were Similar. © 1994, National Stroke Association. All Rights Reserved

Acute flaccid myelitis and Guillain-Barré syndrome in children: A comparative study with evaluation of diagnostic criteria.

Background and purpose Differentiation between acute flaccid myelitis (AFM) and Guillain–Barré syndrome (GBS) can be difficult, particularly in children. Our objective was to improve the diagnostic accuracy by giving recommendations based on a comparison of clinical features and diagnostic criteria in children with AFM or GBS. Methods A cohort of 26 children with AFM associated with enterovirus D68 was compared to a cohort of 156 children with GBS. The specificity of the Brighton criteria, used for GBS diagnosis, was evaluated in the AFM cohort and the specificity of the Centers for Disease Control and Prevention (CDC) AFM diagnostic criteria in the GBS cohort. Results Children with AFM compared to those with GBS had a shorter interval between onset of weakness and nadir (3 vs. 8 days, p < 0.001), more often had asymmetric limb weakness (58% vs. 0%, p < 0.001), and less frequently had sensory deficits (0% vs. 40%, p < 0.001). In AFM, cerebrospinal fluid leukocyte counts were higher, whereas protein concentrations were lower. Spinal cord lesions on magnetic resonance imaging were only found in AFM patients. No GBS case fulfilled CDC criteria for definite AFM. Of the AFM cases, 8% fulfilled the Brighton criteria for GBS, when omitting the criterion of excluding an alternate diagnosis. Conclusions Despite the overlap in clinical presentation, we found distinctive early clinical and diagnostic characteristics for differentiating AFM from GBS in children. Diagnostic criteria for AFM and GBS usually perform well, but some AFM cases may fulfill clinical diagnostic criteria for GBS. This underlines the need to perform diagnostic tests early to exclude AFM in children suspected of atypical GBS