8,770 research outputs found
Tightening Quantum Speed Limits for Almost All States
Conventional quantum speed limits perform poorly for mixed quantum states:
They are generally not tight and often significantly underestimate the fastest
possible evolution speed. To remedy this, for unitary driving, we derive two
quantum speed limits that outperform the traditional bounds for almost all
quantum states. Moreover, our bounds are significantly simpler to compute as
well as experimentally more accessible. Our bounds have a clear geometric
interpretation; they arise from the evaluation of the angle between generalized
Bloch vectors.Comment: Updated and revised version; 5 pages, 2 figures, 1 page appendi
Selecting and implementing overview methods: implications from five exemplar overviews
This is the final version of the article. Available from BioMed Central via the DOI in this record.Background
Overviews of systematic reviews are an increasingly popular method of evidence synthesis; there is a lack of clear guidance for completing overviews and a number of methodological challenges. At the UK Cochrane Symposium 2016, methodological challenges of five overviews were explored. Using data from these five overviews, practical implications to support methodological decision making of authors writing protocols for future overviews are proposed.
Methods
Methods, and their justification, from the five exemplar overviews were tabulated and compared with areas of debate identified within current literature. Key methodological challenges and implications for development of overview protocols were generated and synthesised into a list, discussed and refined until there was consensus.
Results
Methodological features of three Cochrane overviews, one overview of diagnostic test accuracy and one mixed methods overview have been summarised. Methods of selection of reviews and data extraction were similar. Either the AMSTAR or ROBIS tool was used to assess quality of included reviews. The GRADE approach was most commonly used to assess quality of evidence within the reviews.
Eight key methodological challenges were identified from the exemplar overviews. There was good agreement between our findings and emerging areas of debate within a recent published synthesis. Implications for development of protocols for future overviews were identified.
Conclusions
Overviews are a relatively new methodological innovation, and there are currently substantial variations in the methodological approaches used within different overviews. There are considerable methodological challenges for which optimal solutions are not necessarily yet known. Lessons learnt from five exemplar overviews highlight a number of methodological decisions which may be beneficial to consider during the development of an overview protocol.The overview conducted by Pollock [19] was supported by a project grant from the Chief Scientist Office of the Scottish Government. The overview conducted by McClurg [21] was supported by a project grant by the Physiotherapy Research Foundation. The overview by Hunt [22] was supported as part of doctoral programme funding by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South West Peninsula (PenCLAHRC). The overview conducted by Estcourt [20] was supported by an NIHR Cochrane Programme Grant for the Safe and Appropriate Use of Blood Components. The overview conducted by Brunton [23] was commissioned by the Department of Health as part of an ongoing programme of work on health policy research synthesis.
Alex Pollock is employed by the Nursing, Midwifery and Allied Health Professions (NMAHP) Research Unit, which is supported by the Chief Scientist Office of the Scottish Government. Pauline Campbell is supported by the Chief Nurses Office of the Scottish Government
Permutation sampling in Path Integral Monte Carlo
A simple algorithm is described to sample permutations of identical particles
in Path Integral Monte Carlo (PIMC) simulations of continuum many-body systems.
The sampling strategy illustrated here is fairly general, and can be easily
incorporated in any PIMC implementation based on the staging algorithm.
Although it is similar in spirit to an existing prescription, it differs from
it in some key aspects. It allows one to sample permutations efficiently, even
if long paths (e.g., hundreds, or thousands of slices) are needed. We
illustrate its effectiveness by presenting results of a PIMC calculation of
thermodynamic properties of superfluid Helium-four, in which a very simple
approximation for the high-temperature density matrix was utilized
Outcome measures in post-stroke arm rehabilitation trials: do existing measures capture outcomes that are important to stroke survivors, carers, and clinicians?
Objective:
We sought to (1) identify the outcome measures currently used across stroke arm rehabilitation randomized trials, (2) identify and compare outcomes important to stroke survivors, carers and clinicians and (3) describe where existing research outcome measures capture outcomes that matter the most to stroke survivors, carers and clinicians and where there may be discrepancies.
Methods:
First, we systematically identified and extracted data on outcome measures used in trials within a Cochrane overview of arm rehabilitation interventions. Second, we conducted 16 focus groups with stroke survivors, carers and clinicians using nominal group technique, supplemented with eight semi-structured interviews, to identify these stakeholders’ most important outcomes following post-stroke arm impairment. Finally, we described the constructs of each outcome measure and indicated where stakeholders’ important outcomes were captured by each measure.
Results:
We extracted 144 outcome measures from 243 post-stroke arm rehabilitation trials. The Fugl-Meyer Assessment Upper Extremity section (used in 79/243 trials; 33%), Action Research Arm Test (56/243; 23%), and modified Ashworth Scale (53/243; 22%) were most frequently used. Stroke survivors (n = 43), carers (n = 10) and clinicians (n = 58) identified 66 unique, important outcomes related to arm impairment following stroke. Between one and three outcomes considered important by the stakeholders were captured by the three most commonly used assessments in research.
Conclusion:
Post-stroke arm rehabilitation research would benefit from a reduction in the number of outcome measures currently used, and better alignment between what is measured and what is important to stroke survivors, carers and clinicians
Demonstration of non-Markovian process characterisation and control on a quantum processor
In the scale-up of quantum computers, the framework underpinning
fault-tolerance generally relies on the strong assumption that environmental
noise affecting qubit logic is uncorrelated (Markovian). However, as physical
devices progress well into the complex multi-qubit regime, attention is turning
to understanding the appearance and mitigation of correlated -- or
non-Markovian -- noise, which poses a serious challenge to the progression of
quantum technology. This error type has previously remained elusive to
characterisation techniques. Here, we develop a framework for characterising
non-Markovian dynamics in quantum systems and experimentally test it on
multi-qubit superconducting quantum devices. Where noisy processes cannot be
accounted for using standard Markovian techniques, our reconstruction predicts
the behaviour of the devices with an infidelity of . Our results show
this characterisation technique leads to superior quantum control and extension
of coherence time by effective decoupling from the non-Markovian environment.
This framework, validated by our results, is applicable to any controlled
quantum device and offers a significant step towards optimal device operation
and noise reduction
Enhancing the charging power of quantum batteries
Can collective quantum effects make a difference in a meaningful
thermodynamic operation? Focusing on energy storage and batteries, we
demonstrate that quantum mechanics can lead to an enhancement in the amount of
work deposited per unit time, i.e., the charging power, when batteries are
charged collectively. We first derive analytic upper bounds for the collective
\emph{quantum advantage} in charging power for two choices of constraints on
the charging Hamiltonian. We then highlight the importance of entanglement by
proving that the quantum advantage vanishes when the collective state of the
batteries is restricted to be in the separable ball. Finally, we provide an
upper bound to the achievable quantum advantage when the interaction order is
restricted, i.e., at most batteries are interacting. Our result is a
fundamental limit on the advantage offered by quantum technologies over their
classical counterparts as far as energy deposition is concerned.Comment: In this new updated version Theorem 1 has been changed with
Proposition 1. The paper has been published on PRL, and DOI included
accordingl
A qualitative exploration of the effect of visual field loss on daily life in home-dwelling stroke survivors
Objective: To explore the effect of visual field loss on the daily life of community-dwelling stroke survivors. Design: A qualitative interview study. Participants: Adult stroke survivors with visual field loss of at least six months’ duration. Methods: Semi-structured interviews were conducted with a non-purposive sample of 12 stroke survivors in their own homes. These were recorded, transcribed verbatim and analyzed with the framework method, using an inductive approach. Results: Two key analytical themes emerged. ‘Perception, experience and knowledge’ describes participant’s conflicted experience of having knowledge of their impaired vision but lacking perception of that visual field loss and operating under the assumption that they were viewing an intact visual scene when engaged in activities. Inability to recognize and deal with visual difficulties, and experiencing the consequences, contributed to their fear and loss of self-confidence. ‘Avoidance and adaptation’ were two typologies of participant response to visual field loss. Initially, all participants consciously avoided activities. Some later adapted to vision loss using self-directed head and eye scanning techniques. Conclusions: Visual field loss has a marked impact on stroke survivors. Stroke survivors lack perception of their visual loss in everyday life, resulting in fear and loss of confidence. Activity avoidance is a common response, but in some, it is replaced by self-initiated adaptive techniques
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