La donna in Etiopia

La donna in Etiopia / studio del comm. Alberto Pollera Roma : Grafia, 1922 85 p., [9] c. di tav. : ill. ; 24 cm In testa al front.: Ministero delle coloni

Mitochondrial myopathy in rats fed with a diet containing beta-guanidine propionic acid, an inhibitor of creatine entry in muscle cells.

In rats with phosphoryl-creatine depletion (fed a standard Randoin-Causeret diet containing 1% beta-guanidine propionic acid) abnormal mitochondria were observed in slow skeletal muscles, often containing paracrystalline inclusions very like those induced by ischaemia or mitochondrial poisons and in human mitochondrial myopathy

Il regime della proprietà terriera in Etiopia e nella Colonia Eritrea :

Il regime della proprietà terriera in Etiopia e nella Colonia Eritrea : monografia / Alberto Pollera Roma : Tip. Nazionale, di G. Bertero e C., 1913 94 p. ; 25 cm In testa al front.: Ministero delle colonie, Direzione generale degli Affari coloniali, Ufficio di studi colonial

L'ordinamento della giustizia e la procedura indigena in Etiopia e in Eritrea

L'ordinamento della giustizia e la procedura indigena in Etiopia e in Eritrea / monografia del Cav. Alberto Pollera Roma : G. Bertero, 1913 86 p. ; 24 cm in testa al front.: indicazione della collana curata dal Ministero delle colonie

El conocimiento de la Ley 30364 y su relación con la disminución de la violencia familiar en el departamento de Cajamarca, provincia de Jaén en el año 2018

En esta investigación denominada: EL CONOCIMIENTO DE LA LEY DE PROTECCION A LA MUJER Y GRUPO FAMILIAR- LEY N°30364 Y SU RELACION CON LA DISMINUCION DE LA VIOLENCIA FAMILIAR EN LA PROVINCIA DE JAEN – DEPARTAMENTO DE CAJAMARCA, EN EL AÑO 2018 tuvo como objetivo evidenciar si la población - muestra de Cajamarca conoce la existencia de la Ley, denuncia el hecho y si las instituciones obligadas aplican la Ley 30364 Ley para Prevenir, Sancionar y Erradicar la Violencia Contra las Mujeres y los Integrantes del Grupo Familiar. La Metodología de investigación fue correlacional, el tipo de investigación fue básica y de campo, el diseño de la investigación fue cuantitativo y transversal, diseñado para medir el resultado de una población y un tiempo definido. Mediante la encuesta se elaboró y aplicó un estudio, para recabar datos sobre diversos tipos de violencia, pero enfocándonos especialmente en la violencia familiar. También se observó las denuncias registradas ante la Policía Nacional, Fiscalía y de demandas ingresadas ante el Juzgado Especializado Civil de Cajamarca, provincia de Jaén. Finalmente se concluyó que gran cantidad de entre los 100 encuestados desconoce la Ley 30364 Ley para Prevenir, Sancionar y Erradicar la Violencia Contra las Mujeres y los Integrantes del Grupo Familiar debido a que las instituciones correspondientes hacen poco o nada para su difusión en la población. Sin embargo se presencia una disminución de la violencia familiar siendo un reflejo del desarrollo de las buenas costumbres dentro de la comunidad mencionada, con lo que si bien las personas aún están desarrollando una cultura de derecho, las normas básicas de convivencia asi como la lucha por un ambiente de paz son elementos fundamentales para luchar contra la violencia familiar

ENDOCRINE AND AMINO-ACID REGULATION OF LIVER MACROAUTOPHAGY AND PROTEOLYTIC FUNCTION

Endocrine and amino acid regulation of liver macroautophagy and proteolytic function. Am, J. Physiol. 266 (Gastrointest. Liver Physiol. 29): G118-G122, 1994.-Regulation of liver macroautophagy and protein degradation by hormones and direct regulatory amino acids were studied in male 2-mo-old Sprague-Dawley albino rats with the use of the antilipolytic agent 3,5'-dimethylpyrazole (DMP; 12 mg/kg body wt ip) as a stimulatory agent. Injection of DMP decreased glutamine plasma levels and glutamine release from the perfused liver. Autophagic vacuoles were observed in the pericanalicular area of liver cells after 30 min. Levels and release of other regulatory amino acids did not exhibit any significant decrease but subsequently increased. Intraperitoneal administration of glutamine inhibited the proteolytic response. In conclusion, these studies demonstrate that in vivo induction and control of liver macroautophagy and protein degradation by the physiological mechanism (i.e., by shortage of nutrients) involve unbalanced and asynchronous changes in the levels of selected direct regulatory amino acids (i.e., a decrease in glutamine and a subsequent increase in leucine and tyrosine levels)

Proteomic datasets of uninfected and Staphylococcus aureus-infected goat milk

We present a proteomic dataset generated from half-udder Alpine goat milk. The milk samples belonged to 3 groups: i) mid-lactation, low somatic cell count, uninfected milk (MLU, n=3); ii) late lactation, high somatic cell count, uninfected milk (LHU, n=3); and late lactation, high somatic cell count, Staphylococcus aureus subclinically infected milk (LHS, n=3). The detailed description of results is reported in the research article entitled \u201cImpact of Staphylococcus aureus infection on the late lactation goat milk proteome: new perspectives for monitoring and understanding mastitis in dairy goats\u201d. After milk defatting, high speed centrifugation and trypsin digestion of milk with the FASP protocol, peptide mixtures were analyzed by LC-MS/MS on a Q-Exactive. Peptide identification was carried out using Sequest-HT in Proteome Discoverer. Then, the Normalized Abundance Spectrum Factor (NSAF) value was calculated by label free quantitation using the spectral counting approach, and Gene Ontology (GO) annotation by Uniprot was carried out by reporting biological process, molecular function and cellular component. The MS data have been deposited to the ProteomeXchange via the PRIDE with the dataset identifier PXD017243

Impact of gefitinib ('Iressa') treatment on the quality of life of patients with advanced non-small-cell lung cancer

Purpose: Patients with advanced non-small-cell lung cancer (NSCLC) have a short life expectancy; therefore, in addition to increasing their survival, improving their quality of life (QoL) is also an important treatment goal. Methods: We evaluated the QoL of patients with advanced NSCLC who were unfit to receive chemotherapy, failed to respond or progress following prior chemotherapy, who received subsequent treatment with gefitinib ('Iressa') on a compassionate use basis, using a standard QoL questionnaire, (EORTC) QLQ-C30 and the related lung cancer-specific module QLQ-LC13. Results: Analysis of the functional scales showed a trend towards improvement for role, emotional and cognitive scales, while a substantial stability was seen for general QoL scale. Analysis of the symptoms scales of QLQ-C30, showed a trend towards improvement for fatigue, dyspnoea, insomnia, and constipation, after one month of therapy. Fifty-six of the 57 patients were considered evaluable for response. One patient evidenced a partial response (patient is still on response), 29 patients had stable disease for a median duration of 5 months (range 4-7 months), and 26 patients progressed. Conclusions: After treatment with Gefitinib, we observed maintenance of QoL in a group of patients with poor prognosis that would be expected to have a worsening QoL. Furthermore important symptoms like dyspnoea fatigue and pain in other parts, that usually afflict patients with NSCLC, showed a trend toward improvement after only one month of therapy

Effect of the Selective Dry Cow Therapy on Udder Health and Milk Microbiota

Recently, the use of antimicrobials on dairy farms has been significantly limited from both the legislative and consumer points of view. This study aims to check the efficacy of selective dry cow therapy (SDCT) versus blanket dry cow therapy (BDCT) on bovine udder in healthy animals. SDTC is when an antibiotic is administered only to infected cows, compared with BDCT, where all cows receive an antimicrobial, regardless of their infection status. The milk samples were collected from enrolled Holstein Friesian cows 7 days before dry-off (T0) and 10 days after calving (T1) to assess somatic cell count (SCC), intramammary infections (IMIs), and milk microbiota variation. After pre-drying sampling, cows are randomly assigned to the following treatments: internal teat sealant alone (ITS; 24 cows), which is a treatment in a cow that does not receive antibiotics in SDTC, or in combination with intramammary antibiotic treatment (A+ITS; 22 cows). Non-statistically significant results are found between the two treatment groups at T1 for SCC, milk yield, and alpha diversity in milk microbiota. A statistically (p < 0.033) T1 IMI decrease is reported in the A+ITS group, and a significant beta diversity analysis is shown between the two timepoints (p = 0.009). This study confirms the possibility of selective drying without new IMI risk or increased SCC at calving, considering healthy cows without contagious infections and SCC values >200,000 cells/mL in the previous lactation