56 research outputs found
КОНТРОЛЬ РЕЛЬСОВОЙ ЛИНИИ ПО НАПРЯЖЕНИЮ ПИТАЮЩЕГО КОНЦА
The article is devoted to a new method of the control of interaction of rail circuits. The threshold value simultaneously with increased frequency is detected when the train occupies the rail circuit. When the current voltage exceeds the threshold value the train releases the line. The proposed pattern raises shunt sensitivity and extends the length of the rail circuit.Статья посвящена новому методу контроля взаимовлияния рельсовых цепей. В момент занятия поездом рельсовой линии фиксируется пороговое напряжение с участием повышенной частоты, а освобождение ее происходит при превышении текущим напряжением его порогового значения. Используемая схема повышает шунтовую чувствительность и увеличивает длину рельсовой цепи
New behavioral forms of sportsman students identification in university digital educational reality
The relevance of the research is due to a wide range of changes in the University educational reality caused by the influence of the Internet, computers, smartphones, mobile devices and modern gadgets on the behavioural forms of student identification. These processes are becoming a matter of particular concern to the public and University teachers. In this regard, this study reveals the features of the value priorities of the University digital educational reality, which modify the behavioural forms of student identification. In the course of pedagogical modelling, which is the leading research method, the phenomenon of new behavioural forms of student identification is identified as the leading idea of the University digital educational reality. This article reveals the key values of student identity identification in the University digital educational reality. The structure and content of new behavioural forms of student identification are established. Based on the research materials, the correction module of new behavioural forms of student identification in the University digital educational reality is justified. The module effectiveness is proved by the results of using new behavioural forms of student identification in the University educational process. The materials of the article are recommended to teachers, methodologists, organizers of the educational process and University students
Применение нейросетевой модели для оптимизации схемы лечения больных бронхиальной астмой различного возраста
The paper is concerned with bronchial asthma clinical features. Complications, co-existing diseases, clinical and pathogenic types of asthma are considered. Three hundred patients were examined. Treatment results were analyzed and commented. An improvement in the treatment of asthma patients using neural networks is offered.Обсуждаются вопросы различия в клинической картине бронхиальной астмы (БА) у 300 больных разного возраста с учетом наличия осложнений, сопутствующих заболеваний и клинико-патогенетических вариантов; приводятся комментарии по результатам лечения больных и предлагается способ оптимизации лечения больных БА различного возраста с применением нейросетевого моделирования
Thin Structure of Differentially Hardened 100m Rails
The methods of modern physical materials science are used to study the structural phase state, defective substructure, and properties of 100 m rails of the DT350 category after extremely long operation. The studies were carried out at different distances of 0, 2, 10 mm along the central axis and the fillet. It is shown that differentiated hardening is accompanied by the formation of a morphologically diverse structure, represented by grains of lamellar perlite, ferrite-carbide mixture, and structurally free ferrite.Методами современного физического материаловедения исследованы структурно-фазовое состояние, дефектная субструктура и свойства 100-м рельсов категории ДТ350 после экстремально длительной эксплуатации. Исследования проводились на различном расстоянии: 0, 2, 10 мм по центральной оси и выкружке. Показано, что дифференцированная закалка сопровождается формированием морфологически многоплановой структуры, представленной зернами пластинчатого перлита, феррито-карбидной смеси и структурно-свободного феррита.Работа выполнена по гранту при финансовой поддержке РФФИ (проект № 19–32–60001)
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Sweet taste pleasantness is modulated by morphine and naltrexone
Rodent models highlight the key role of µ-opioid receptor (MOR) signaling in palatable food consumption. In humans however, the effects of MOR stimulation on eating and food liking remain unclear. In a bidirectional psychopharmacological cross-over study, 49 healthy men underwent a sweet taste paradigm following double-blind administration of the MOR agonist morphine, placebo, and the opioid antagonist nalt rexone. We hypothesized that behaviors regulated by the endogenous MOR system would be enhanced by MOR agonism, and decreased by antagonism. The strongest drug effects were expected for the sweetest (high-calorie) sucrose solution, as reported in rodents. However, very sweet sucrose-water solutions are considered sickly and aversive by many people (called sweet dislikers). Since both sweet likers and dislikers were tested, we were able to assess whether MOR manipulations affect pleasantness ratings differently depending on both subjective and objective value. As hypothesized, MOR stimulation with morphine increased pleasantness of the sweetest of five sucrose solutions, without enhancing pleasantness of the lower-sucrose solutions. For opioid antagonism, an opposite pattern was observed for the sweetest drink only. This bidirectional effect of agonist and antagonist treatment is consistent with rodent findings that MOR manipulations most strongly affect the highest-calorie foods. Importantly, the observed drug effects on pleasantness of the sweetest drink did not differ between sweet likers and dislikers. We speculate that the MOR system promotes survival in part by increasing concordance between the objective (caloric) and subjective (hedonic) value of food stimuli, so that feeding behaviour becomes more focused on the richest food available
High locomotor reactivity to novelty is associated with an increased propensity to choose saccharin over cocaine: new insights into the vulnerability to addiction.
Drug addiction is associated with a relative devaluation of natural or socially-valued reinforcers that are unable to divert addicts from seeking and consuming the drug. Before protracted drug exposure, most rats prefer natural rewards, such as saccharin, over cocaine. However, a subpopulation of animals prefer cocaine over natural rewards and are thought to be vulnerable to addiction. Specific behavioral traits have been associated with different dimensions of drug addiction. For example, anxiety predicts loss of control over drug intake whereas sensation seeking and sign-tracking are markers of a greater sensitivity to the rewarding properties of the drug. However, how these behavioral traits predict the disinterest for natural reinforcers remains unknown. In a population of rats, we identified sensation seekers (HR) on the basis of elevated novelty-induced locomotor reactivity, high anxious rats (HA) based on the propensity to avoid open arms in an elevated-plus maze and sign-trackers (ST) that are prone to approach, and interaction with, reward-associated stimuli. Rats were then tested on their preference for saccharin over cocaine in a discrete-trial choice procedure. We show that HR rats display a greater preference for saccharin over cocaine compared with ST and HA whereas the motivation for the drug was comparable between the three groups. The present data suggest that high locomotor reactivity to novelty, or sensation seeking, by predisposing to an increased choice toward non-drug rewards at early stages of drug use history, may prevent the establishment of chronic cocaine use.This work was funded by an INSERM AVENIR and Agence Nationale de la Recherche (ANR) ANR12 SAMA00201 grant to DB, the région Poitou-Charentes, an AXA research fund fellowship to ABR, and a Ministère de la Recherche et de la Technologie grant to NV. AM was supported by the Behavioural and Clinical Neuroscience Institute of Cambridge.This is the accepted manuscript of a paper published in Neuropsychopharmacology (2015) 40, 577–589; doi:10.1038/npp.2014.204; published online 17 September 2014
A distributed type adaptive matching device for decameter range antennas
The paper considers an antenna-matching device in the form of a transmission line segment (for the decameter range — a delay line composed of several segments of a low-pass filter). Depending on the phase of the reflection coefficient in a given section, additional capacitors may be connected to or disconnected from the segment
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