2,432 research outputs found
Action Type Geometrical Equivalence of Representations of Groups
For every variety of algebras and every algebras in these variety we can
consider an algebraic geometry. Algebras may be many sorted (not necessarily
one sorted) algebras. A set of sorts is fixed for each variety. This theory can
be applied to the variety of representations of groups over fixed commutative
ring with unit. We consider a representation as two sorted algebra. We
concentrate on the case of the action type algebraic geometry of
representations of groups. In this case algebraic sets are defined by systems
of action type equations and equations in the acting group are not considered.
This is the special case, which cannot be deduced from the general theory. In
this paper the following basic notions are introduced: action type geometrical
equivalence of two representations, action type quasi-identity in
representations, action type quasi-variety of representations, action type
Noetherian variety of representations, action type geometrically Noetherian
representation, action type logically Noetherian representation.Comment: 35 page
The evolution of genetic architectures underlying quantitative traits
In the classic view introduced by R. A. Fisher, a quantitative trait is
encoded by many loci with small, additive effects. Recent advances in QTL
mapping have begun to elucidate the genetic architectures underlying vast
numbers of phenotypes across diverse taxa, producing observations that
sometimes contrast with Fisher's blueprint. Despite these considerable
empirical efforts to map the genetic determinants of traits, it remains poorly
understood how the genetic architecture of a trait should evolve, or how it
depends on the selection pressures on the trait. Here we develop a simple,
population-genetic model for the evolution of genetic architectures. Our model
predicts that traits under moderate selection should be encoded by many loci
with highly variable effects, whereas traits under either weak or strong
selection should be encoded by relatively few loci. We compare these
theoretical predictions to qualitative trends in the genetics of human traits,
and to systematic data on the genetics of gene expression levels in yeast. Our
analysis provides an evolutionary explanation for broad empirical patterns in
the genetic basis of traits, and it introduces a single framework that unifies
the diversity of observed genetic architectures, ranging from Mendelian to
Fisherian.Comment: Minor changes in the text; Added supplementary materia
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