Experimental Test bed to De-Risk the Navy Advanced Development Model

This paper presents a reduced scale demonstration test-bed at the University of Texas’ Center for Electromechanics (UT-CEM) which is well equipped to support the development and assessment of the anticipated Navy Advanced Development Model (ADM). The subscale ADM test bed builds on collaborative power management experiments conducted as part of the Swampworks Program under the US/UK Project Arrangement as well as non-military applications. The system includes the required variety of sources, loads, and controllers as well as an Opal-RT digital simulator. The test bed architecture is described and the range of investigations that can be carried out on it is highlighted; results of preliminary system simulations and some initial tests are also provided. Subscale ADM experiments conducted on the UT-CEM microgrid can be an important step in the realization of a full-voltage, full-power ADM three-zone demonstrator, providing a test-bed for components, subsystems, controls, and the overall performance of the Medium Voltage Direct Current (MVDC) ship architecture.Center for Electromechanic

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.

The scandium effect in multicomponent alloys

Despite its excellent elemental properties, lightweight nature and good alloying potential, scandium has received relatively little attention in the manufacturing community. The abundance of scandium in the Earth's crust is quite high. It is more abundant than silver, cobalt, lead and tin. But, because scandium is so well dispersed in the lithosphere, it is notoriously difficult to extract in commercial quantities – hence low market availability and high cost. Scandium metallurgy is still a largely unexplored field – but progress is being made. This review aims to summarise advances in scandium metallurgical research over the last decade. The use of scandium as a conventional minor addition to alloys, largely in structural applications, is described. Also, more futuristic functional applications are discussed where details of crystal structures and peculiar symmetries are often of major importance. This review also includes data obtained from more obscure sources (especially Russian publications) which are much less accessible to the wider community. It is clear that more fundamental research is required to elevate the status of scandium from a laboratory-based curiosity to a mainstream alloying element. This is largely uncharted territory. There is much to be discovered

Synchronization of Multiple Pulsed Alternators Discharging into an EM Launcher

As the energy level in the projectile increases it becomes necessary to use multiple pulsed alternators discharging in parallel into the EM launcher. Another reason for having more than one machine is to compensate torque and gyroscopic effects of the pulsed alternator. This requires that machines be built in counter-rotating pairs. These machines are identical in all respects except for their direction of rotation. A study was conducted to determine how the machines can be motored so that they stay in lock step in speed and phase as they are motored to full speed. The methods of connecting these multiple machines are discussed. The aim of the connection scheme is to allow the machines to naturally stay locked in speed and phase throughout its operating range. Sensitivity of the performance of these machines to small variations in the machine parameters, which is to be expected in the machines, is discussed. Sensitivity of the discharge performance to small phase angle mismatches due to tolerances is also discussed. To verify the conclusions of the study an experiment was performed on two identical 50 kVA machines discharging into a low impedance load. The motoring system that is discussed in the study was implemented in this experiment which kept the machines in lock step. This motoring system is described. Thereafter discharges were made at various speeds and field current levels. Phase angle mismatches were introduced between the two machines to see how it affected current sharing. The results and conclusions of these tests are presented in this paper.Center for Electromechanic

A collaborative early-stage ship design environment

Recent advances in sensor and weapons systems are significantly increasing the electrical power that is required and the thermal loads that must be dissipated onboard US Navy ships. Thus, design tools and methods must bring detailed consideration of all disciplines early in the design process, including electrical, thermal and controls in addition to the traditional naval architecture and marine engineering. Effective interface of the multiple disciplines demands a collaborative design process. The Electric Ship Research and Development Consortium (ESRDC) has developed the backbone structure of a collaborative design environment with the goal of bringing together many disciplines early in the ship design process. This design environment brings many innovations, especially in the arena of simultaneous collaborative design. This paper describes the Smart Ship System Design (S3D) environment as developed to date, along with overall and discipline-specific visions of implementation of the environment in ship design.Center for Electromechanic