1,792 research outputs found
Reflexos do Mercosul na indústria publicitária brasileira
O presente artigo procede aum balanço geral dosmercados publicitários dospaíses membros do Mercosule examina a presença dasagências de propaganda eempresas de comunicaçãobrasileiras no quarto maiorbloco econômico do planeta.P a l a v r a s - c h a v e s :Mercosul, publicidade, mídi
Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage.
Mutat Res. 2003 Apr 20;536(1-2):61-7.
Role of haemoglobin in the protection of cultured lymphocytes against diepoxybutane (DEB), assessed by in vitro induced chromosome breakage.
Porto B, Chiecchio L, Gaspar J, Faber A, Pinho L, Rueff J, Malheiro I.
Laboratory of Cytogenetics, Instituto Ciências Biomédicas Abel Salazar (ICBAS), Largo do Prof. Abel Salazar, No. 2, 4099-003, Porto, Portugal.
Abstract
Diepoxybutane (DEB) is an alkylating agent that can be used to assess chromosome instability in repair-deficient subjects. Previous authors investigated the role of red blood cells (RBC) in determining individual susceptibility to DEB in normal healthy donors, and demonstrated that a polymorphic enzyme in RBC, Glutathione S-transferase T1 (GSTT1), is involved in DEB detoxification. In the present work we studied the influence of individual GSTM1 and GSTT1 genotypes and the presence of RBC on the frequency of DEB-induced chromosome breakage in lymphocyte cultures from normal individuals and, in particular, the influence of isolated components of RBC: RBC membranes, RBC lysate, and haemoglobin. Our results confirm that individual GSTT1 genotypes modulate the level of genetic lesions induced by DEB; however, this effect was not sufficient to explain the highly significant variation in chromosome breakage between whole blood and RBC-depleted cultures. We showed that RBC can protect cultured lymphocytes against chromosome breakage induced by DEB and we demonstrated the particular role of haemoglobin in the protective effect.
PMID: 12694746 [PubMed - indexed for MEDLINE
Universal Critical Behavior of Aperiodic Ferromagnetic Models
We investigate the effects of geometric fluctuations, associated with
aperiodic exchange interactions, on the critical behavior of -state
ferromagnetic Potts models on generalized diamond hierarchical lattices. For
layered exchange interactions according to some two-letter substitutional
sequences, and irrelevant geometric fluctuations, the exact recursion relations
in parameter space display a non-trivial diagonal fixed point that governs the
universal critical behavior. For relevant fluctuations, this fixed point
becomes fully unstable, and we show the apperance of a two-cycle which is
associated with a novel critical behavior. We use scaling arguments to
calculate the critical exponent of the specific heat, which turns out
to be different from the value for the uniform case. We check the scaling
predictions by a direct numerical analysis of the singularity of the
thermodynamic free-energy. The agreement between scaling and direct
calculations is excellent for stronger singularities (large values of ). The
critical exponents do not depend on the strengths of the exchange interactions.Comment: 4 pages, 1 figure (included), RevTeX, submitted to Phys. Rev. E as a
Rapid Communicatio
Monitoring the salt marsh vegetation and flora of the Baixo Vouga Lagunar (Ria of Aveiro, Portugal)
El carácter transicional de la Ría de Aveiro le confiere una riqueza florística singular, integrando comunidades vegetales típicas de las
regiones Eurosiberiana y Mediterránea. La implantación del Proyecto Desenvolvimento Agrícola do Vouga (PDAV) va a provocar una
modificación de las tasas de encharcamiento y una reducción gradual de la salinidad, factores ecológicos determinantes para muchas de las
comunidades halófilas y helofíticas. El presente trabajo pretende contribuir a un mejor conocimiento de la tipología de la vegetación local, que
sirva como base para desarrollar un programa de monitorización adecuado que detecte las alteraciones en los patrones espacio- temporales
de la vegetación de los sistemas húmedos. Teniendo como objetivo seleccionar los puntos de muestreo donde instalar las parcelas
permanentes de monitorización, se realizó una caracterización de la flora y la vegetación a través de trece transectos utilizando una
aproximación simplificada al método de Braun- Blanquet. Una vez identificados los tipos de vegetación - en función de su composición
florística, corología y ecología - fueron seleccionados al azar inventarios representativos de cada tipo, en los que han sido instaladas dichas
parcelas.The transitional
biogeographic character of the Ria de Aveiro lagoon area confers it a singular floristic richness, integrating plant communities typical for the
Eurosiberian as well as Mediterranean Region. The implementation of the Agricultural Development Plan of the Lower Vouga area (PDAV) in
the near future is expected to result in noticeable changes in the tidal submersion regime and a gradual reduction of salinity levels, which are
determining ecological factors for many of the halophytic and helophytic plant communities. The present work pretends to contribute to a
better knowledge of the local vegetation types and, thereby, to the implementation of an adequate monitoring programme for detecting
changes in the spatio-temporal vegetation patterns of the wetlands. With the objective to select the locations for the installation of permanent
quadrats, the vegetation of the wetlands was described along 13 transects using a simplified Braun-Blanquet approach. A total of 24 local
vegetation types were recognised, 23 of which were selected for the current monitoring programme
From Bloch Oscillations to a Steady-State Current in Strongly Biased Mesoscopic Devices
It has long been known that quantum particles in a periodic lattice exhibit
an oscillatory motion that is solely driven by a constant and uniform force
field. In a strongly biased mesoscopic device, this would appear as an ongoing
time-dependent current oscillation (a Bloch oscillation) but, even when
electrons can move coherently and without scattering, a steady-state regime of
charge transport (a Landauer current) have been seen to quickly emerge. Here,
we theoretically investigate the non-equilibrium current dynamics of a strongly
biased two-terminal mesoscopic device, in order to show that such a system can
exhibit Bloch oscillations as a transient regime that relaxes into a Landauer
steady-state from charge being drained into the leads. Analytical results from
the one-dimensional Wannier-Stark ladder problem are combined with numerical
quantum time-evolution of a tight-binding toy model with finite leads to
characterize the decay times of transient Bloch oscillations and establish the
conditions under which they can occur.Comment: Preliminary Version (13 pages + 12 Figures). Comments and Suggestions
are Welcome
Ground-motion networks in the Groningen field: usability and consistency of surface recordings
Several strong-motion networks have been installed in the Groningen gas field in the Netherlands to record ground motions associated with induced earthquakes. There are now more than 450 permanent surface accelerographs plus a mobile array of 450 instruments, which, in addition to many instrumented boreholes, yield a wealth of data. The database of recordings has been of fundamental importance to the development of ground-motion models that form a key element of the seismic hazard and risk estimations for the field. In order to maximise the benefit that can be derived from these recordings, this study evaluates the usability of the recordings from the different networks, in general terms and specifically with regards to the frequency ranges with acceptable signal-to-noise ratios. The study also explores the consistency among the recordings from the different networks, highlighting in particular how a configuration error was identified and resolved. The largest accelerograph network consists of instruments housed in buildings around the field, frequently installed on the lower parts of walls rather than on the floor. A series of experiments were conducted, using additional instruments installed adjacent to these buildings and replicating the installation configuration in full-scale shake table tests, to identify the degree to which structural response contaminated the recordings. The general finding of these efforts was that for PGV and oscillator periods above 0.1 s, the response spectral ordinates from these recordings can be used with confidence
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