3 research outputs found

    Quantification et scalarité: Le fonctionnement de tant/autant (que)

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    By analysing a corpus of occurences of quantifying scalar markers (au)tant (. que), and the different meaning effects produced according to their syntactic scope, this contribution aims at showing that the concept of scalarity deserves to be considered, beside that of quantification, as a relevant methodological tool.SCOPUS: re.jinfo:eu-repo/semantics/publishe

    La scalarité aux fondements de la distinction entre constructions équative et similative?

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    Lobjectif de la présente contribution est dévaluer, à partir des données du français, en quelle mesure la scalarité est pertinente pour opérer une distinction entre les deux systèmes linguistiques qui, dans de nombreuses langues dEurope en particulier, sont associés à la comparaison dégalité : les constructions équatives et similatives (cf. Haspelmath & Buchholz 1998). Ces constructions sont respectivement illustrées par les exemples français (1a) et (2a), auxquels sont jointes les paraphrases de Haspelmath & Buchholz (1998 : 278). Celles-ci visent à expliciter au niveau sémantique la base commune et les différences entre les deux tours : (1a) Robert est aussi grand que Maria. [~± Robert is tall to the same extent as Maria] (2a) Il chante comme un rossignol. [~± He sings in the same way as a nightingale] Létude du système des constructions équatives et similatives, ainsi que des constructions exclamatives voisines en français moderne, a mis en évidence que la propriété scalaire jouait un rôle bien plus complexe quinitialement attendu dans le départ entre les diverses constructions. Dans le cas des équatives, limportance de leur lien inhérent avec la scalarité à travers leurs marqueurs se combine avec un impact syntaxo-discursif, qui permet de moduler lexpression des différentes lectures scalaires. Pour ce qui concerne les similatives, les effets scalaires sont essentiellement obtenus par des contextes discursifs. Ceux-ci ne sont nullement inhérents aux composantes de la construction, et en particulier au marqueur 'comme'

    Radical Prostatectomy after Vascular Targeted Photodynamic Therapy with Padeliporfin: Feasibility, and Early and Intermediate Results

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    PURPOSE: Vascular targeted photodynamic therapy with TOOKAD® is a new therapeutic option for localized prostate cancer management. The objectives of this study were to assess the feasibility of radical prostatectomy after vascular targeted photodynamic therapy and describe functional and oncologic outcomes. MATERIALS AND METHODS: We retrospectively included in study 45 patients who underwent salvage radical prostatectomy after vascular targeted photodynamic therapy for recurrent prostate cancer at a total of 14 surgical centers in Europe between October 2008 and March 2017. Of the 42 radical prostatectomies performed 16 were robot-assisted, 6 were laparoscopic and 20 were open surgery. Primary end points were morbidity and technical difficulties. Secondary end points were early and intermediate postoperative functional and oncologic outcomes. RESULTS: Median operative time was 180 minutes (IQR 150-223). Median blood loss was 200 ml (IQR 155-363). According to the surgeons the surgery was easy in 29 patients (69%) and difficult in 13 (31%). Nerve sparing was feasible in 14 patients (33%). Five postoperative complications (12%) were found, including 2 Clavien I, 2 Clavien II and 1 Clavien IIIB complications. Of the cases 13 (31%) were pT3 and 21 (50%) were pT2c. Surgical margins were positive in 13 patients (31%). Prostate specific antigen was undetectable at 6 to 12 months in 37 patients (88%). Nine patients underwent complementary radiotherapy. Four patients had final prostate specific antigen greater than 0.2 ng/ml at a median followup of 23 months (IQR 12-36). At 1 year 27 patients (64%) were completely continent (no pads) and 10 (24%) had low incontinence (1 pad). Four patients (11%) recovered potency without treatment and 23 (64%) recovered potency with appropriate treatment. CONCLUSIONS: Salvage radical prostatectomy after vascular targeted photodynamic therapy treatment was feasible and safe without difficulty for most of the surgeons.status: publishe
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