The objects of nostalgia to rethink the relationship with time: practices and memories of two generations.

La ricerca di tesi qui presentata nasce con lo scopo di sondare la natura degli oggetti affettivi attraverso l’analisi dei lavori di campo da me svolti tra il 2016 e il 2019: il lavoro di campo all’interno dei Musei degli oggetti ordinari di Marseille e Parma (ricerca in ambiente museale) ed il lavoro di campo condotto all’interno di 28 abitazioni dell’Emilia Romagna (ricerca in ambiente domestico) comprendente un confronto generazionale tra sessantenni e trentenni. In particolare, con il lavoro qui presentato ho voluto cercare di comprendere, per mezzo di un’attenta analisi del legame uomo / cosa, la natura del rapporto che gl’individui tessono con le diverse dimensioni temporali della loro vita: passato, presente, futuro. La mia ricerca di tesi nasce difatti dal presupposto che gli oggetti affettivi (qui definiti “oggetti della nostalgia”) si inscrivono nella storia dei loro proprietari, essi evocano memorie, ricordi, ma anche valori e modi di vivere / di essere. Gli oggetti affettivi essendo in grado di preservare nel tempo una loro “funzionalità”, finiscono per preservare nella loro valenza simbolica ed affettiva frammenti di memorie in grado di orientare i loro proprietari nell’elaborazione del passato, ma anche di aiutarli nella creazione di un tempo presente e futuro sempre più felice e consapevole. Essi, in virtù del legame che li unisce intimamente ai loro proprietari, mantengono in vita ciò che apparentemente non esiste più, preservano l’assente nella loro presenza coniugando l’invisibile al visibile, l’immaterialità alla materia.Cette thèse a pour but d'explorer la nature des objets affectifs à travers l'analyse d'études sur le terrain que j'ai effectuées entre 2016 et 2019 : une étude de terrain au sein du Musée des Objets Ordinaires de Marseille et de Parme (recherche dans un environnement muséal) et une étude de terrain conduite à l'intérieur de 28 habitations en Émilie-Romagne (recherche dans un environnement domestique). Cette recherche comprend une comparaison entre deux générations : les sexagénaires et les trentenaires. Plus précisément, à l'aide de la réflexion présentée ici, j'ai voulu essayer de comprendre, au moyen d'une analyse approfondie, la relation homme-objet, la nature du lien que les individus tissent avec les différentes dimensions temporelles de leur vie : le passé, le présent et le futur. Mon travail de recherche se fonde en effet sur l'hypothèse que les objets affectifs (ici définis comme “les objets de la nostalgie”) s'inscrivent dans l'histoire de leurs propriétaires et que ceux-ci évoquent des souvenirs, mais aussi des valeurs et différentes manières de vivre et d'exister. Pouvant conserver leur “fonctionnalité” dans le temps, les objets affectifs finissent par préserver dans leur valeur symbolique et affective, des fragments de mémoire en mesure de guider leurs propriétaires dans l’élaboration du passé, mais également dans la construction d’un temps présent de plus en plus heureux et conscient. Ceux-ci, en vertu du lien qui les unie de manière intime avec leurs propriétaires, maintiennent en vie ce qui n’existe apparemment plus, et, par leur présence, préservent ce qui est absent en conjuguant l’invisible avec le visible, l’immatérialité avec la matière.This thesis aims to explore the nature of affective objects by analysing the fieldworks I carried out between 2016 and 2019. The fieldwork at the Museum of Ordinary Objects of Marseille and Parma (museum research), and the fieldwork I carried out in 28 homes in Emilia Romagna (domestic research), which includes a comparison between two generations, the 60-year-olds and the 30-year-olds. More specifically, the purpose of the work presented here is to try to understand - by means of a precise analysis of the human-object relationship - the nature of the connection that individuals build with the different temporal dimensions of their lives: the past, the present and the future. My thesis research is based on the assumption that affective objects (defined here as «objects of nostalgia», become part of the history of their owners. That these objects can evoke memories but also values and ways of living / existing. Having the capacity to preserve their «functionality» across time, affective objects end up preserving - in their symbolic and affective value - fragments of memories capable of guiding their owners through the construction of their past, and also helping them to build a present and an ever more happy and conscious future. Thanks to the intimate connection they have with their owners, affective objects keep alive what seems to no longer exist. Their presence helps preserve the absent, combining the invisible and the visible, the intangible and the tangible

ECMO for COVID-19 patients in Europe and Israel

Since March 15th, 2020, 177 centres from Europe and Israel have joined the study, routinely reporting on the ECMO support they provide to COVID-19 patients. The mean annual number of cases treated with ECMO in the participating centres before the pandemic (2019) was 55. The number of COVID-19 patients has increased rapidly each week reaching 1531 treated patients as of September 14th. The greatest number of cases has been reported from France (n = 385), UK (n = 193), Germany (n = 176), Spain (n = 166), and Italy (n = 136) .The mean age of treated patients was 52.6 years (range 16–80), 79% were male. The ECMO configuration used was VV in 91% of cases, VA in 5% and other in 4%. The mean PaO2 before ECMO implantation was 65 mmHg. The mean duration of ECMO support thus far has been 18 days and the mean ICU length of stay of these patients was 33 days. As of the 14th September, overall 841 patients have been weaned from ECMO support, 601 died during ECMO support, 71 died after withdrawal of ECMO, 79 are still receiving ECMO support and for 10 patients status n.a. . Our preliminary data suggest that patients placed on ECMO with severe refractory respiratory or cardiac failure secondary to COVID-19 have a reasonable (55%) chance of survival. Further extensive data analysis is expected to provide invaluable information on the demographics, severity of illness, indications and different ECMO management strategies in these patients

L'augmentation de la circulation collatérale non coronarienne (l'hypothèse d'une méthode alternative de revascularisation myocardique)

La circulation collatérale non coronarienne (CCNC) perfuse le cœur en provenant d artères bronchiques, médiastinales et péricardiques. L éventualité que la CCNC puisse être artificiellement augmentée pour fournir un traitement alternatif pour les patients ischémiques représente une hypothèse intrigante sans réponse en raison de la nature difficile de ce champ derecherche. En se basant sur plusieurs aspects, tel que (1) l existence des collatérales naturelles entre les artères coronaires et les artères thoraciques internes (ATIs), (2) les effets potentiels de la ligature des ATIs; (3) la capacité des ATIs de développer d importantes branches collatérales ; (4) et la disponibilité actuelle des facteurs de croissance vasculaire, l hypothèse ici décrite est que l augmentation de la CCNC pourrait représenter une stratégie alternative d apport sanguin au coeur.Ainsi, l association d occlusion des ATIs et de l administration des facteurs de croissance pourrait représenter un moyen de poursuivre cet objectif. Pour le premier travail de recherche, nous avons établi un modèle canin.Noncoronary collateral circulation (NCCC) comes to the heart from mediastinal, bronchial, and pericardial channels. Whether NCCC can somehow be augmented to provide an alternative therapy for ischemic patients is an intriguing hypothesis with no clear answer yet due to the challenging nature of this research field. Based on several aspects, such as (1) the occurrence of natural collaterals between coronary and the internal thoracic arteries (ITAs), (2) the potentialhemodynamic effects of ITAs ligation, (3) the potential of ITAs for developing important collateral branches, and (4) the current availability of angiogenic growth factors, the hypothesis herein is that enhancement of NCCC may represent an alternative myocardial blood supply strategy, and that combining ITAs occlusion with angiogenic growth factors may represent a way to achieve this objective. We established an ischemic canine model for first experiment.PARIS11-SCD-Bib. électronique (914719901) / SudocSudocFranceF

Superficial femoral vein as substitute for pulmonary artery reconstruction after resection for bronchovascular fistula

Post-lobectomy bronchovascular fistula (BVF) associated with massive hemoptysis is a rare but life-threatening complication. Surgical options include completion pneumonectomy or BVF resection with end-to-end anastomosis of the airways and reconstruction of the pulmonary artery (PA) by interposition of an appropriate substitute. We report PA resection and successful reconstruction by interposition of an autologous reversed superficial femoral vein (SFV) segment for this purpose