On the Positive Effects of Overcon fident Self-Perception in Teams

In this paper, we study the individual payoff effects of overconfident self-perception in teams. In particular, we demonstrate that the welfare of an overconfident agent in a team of one rational and one overconfident agent or a team of two overconfident agents can be higher than that of the members of a team of two rational agents. This result holds irrespective of the assumption about the agents' awareness of their colleague's bias. Moreover, we show that an overcondent agent is always better of when he is unaware of a potential bias of his colleague

On the Positive Effects of Overcon fident Self-Perception in Teams

In this paper, we study the individual payoff effects of overconfident self-perception in teams. In particular, we demonstrate that the welfare of an overconfident agent in a team of one rational and one overconfident agent or a team of two overconfident agents can be higher than that of the members of a team of two rational agents. This result holds irrespective of the assumption about the agents' awareness of their colleague's bias. Moreover, we show that an overcondent agent is always better of when he is unaware of a potential bias of his colleague.Overconfidence; Team Production

Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance

INTRODUCTION Endosomal toll-like receptors (TLRs) have recently emerged as potential contributors to the inflammation observed in human and rodent models of rheumatoid arthritis (RA). This study aims to evaluate the role of endosomal TLRs and in particular TLR7 in the murine collagen induced arthritis (CIA) model. METHODS CIA was induced by injection of collagen in complete Freund's adjuvant. To investigate the effect of endosomal TLRs in the CIA model, mianserin was administered daily from the day of disease onset. The specific role of TLR7 was examined by inducing CIA in TLR7-deficient mice. Disease progression was assessed by measuring clinical score, paw swelling, serum anti-collagen antibodies histological parameters, cytokine production and the percentage of T regulatory (Treg) cells. RESULTS Therapeutic administration of mianserin to arthritic animals demonstrated a highly protective effect on paw swelling and joint destruction. TLR7-/- mice developed a mild arthritis, where the clinical score and paw swelling were significantly compromised in comparison to the control group. The amelioration of arthritis by mianserin and TLR7 deficiency both corresponded with a reduction in IL-17 responses, histological and clinical scores, and paw swelling. CONCLUSIONS These data highlight the potential role for endosomal TLRs in the maintenance of inflammation in RA and support the concept of a role for TLR7 in experimental arthritis models. This study also illustrates the potential benefit that may be afforded by therapeutically inhibiting the endosomal TLRs in RA

A survey thesis of the personal reading preferences of children in the intermediate grades

Thesis (Ed.M.)--Boston Universit

Antifreeze Proteins in the Primary Urine of Larvae of the Beetle \u3cem\u3eDendroides canadensis\u3c/em\u3e

To avoid freezing while overwintering beneath the bark of fallen trees, Dendroides canadensis (Coleoptera: Pyrochroidae) larvae produce a family of antifreeze proteins (DAFPs) that are transcribed in specific tissues and have specific compartmental fates. DAFPs and associated thermal hysteresis activity (THA) have been shown previously in hemolymph and midgut fluid, but the presence of DAFPs has not been explored in primary urine, a potentially important site that can contain endogenous ice-nucleating compounds that could induce freezing. A maximum mean THA of 2.65±0.33°C was observed in primary urine of winter-collected D. canadensis larvae. THA in primary urine increased significantly through autumn, peaked in the winter and decreased through spring to levels of 0.2–0.3°C in summer, in a pattern similar to that of hemolymph and midgut fluid. THA was also found in hindgut fluid and excreted rectal fluid, suggesting that these larvae not only concentrate AFPs in the hindgut, but also excrete AFPs from the rectal cavity. Based on dafp transcripts isolated from Malpighian tubule epithelia, cDNAs were cloned and sequenced, identifying the presence of transcripts encoding 24 DAFP isoforms. Six of these Malpighian tubule DAFPs were known previously, but 18 are new. We also provide functional evidence that DAFPs can inhibit ice nucleators present in insect primary urine. This is potentially critical because D. canadensis larvae die if frozen, and therefore ice formation in any body fluid, including the urine, would be lethal

A quantitative ecological study of selected nearshore marine plants and animals at the Diablo Canyon power plant site: a pre-operational baseline, 1973-1978

Biologists of the California Department of Fish and Game, under contract with the Pacific Gas and Electric Company, conducted surveys or intertidal and subtidal plants and animals 1n the vicinity of the Diablo Canyon Nuclear Power Plant for the summer of 1973 through 1978. Abundances of the dominant plants and animals were obtained at random as well as permanent stations in Diablo Cove as well as nearby control areas. A total of 643 permanent and random stations were surveyed, 262 in the intertidal and 381 in the subtidal. Natural as well as man-caused occurrences have resulted in several significant changes in plant and animal abundance in the study areas; these include the arrival of the southern front or the sea otter population in Diablo Cove in 1974; a strong red tide bloom in the fall of 1974; and the release of copper ions from the power plant condenser tubes into Diablo Cove during the summer of 1974. Our intertidal and subtidal random station data have shown a strong decline in giant red sea urchin, Strongylocentrotus franciscanus, densities and the surface canopy kelp, Nereocystis/leutkeana, and a corresponding increase in the subcanopy kelps, Pterygophora and Laminaria. Seasonal patterns of abundance of foliose red algae at random intertidal stations occurred at all study areas. Several species intertidal and subtidal invertebrates showed increasing or decreasing trends in levels of abundance during the five year study period covered by the report. Some of these changes in abundance may be related to the natural man-caused impacts mentioned above. (Document has 728 pages

Social fairness and ecological integrity: strategy and action for a moral economy

Journal ArticleOn March 4th, 2011, 44 participants gathered at the Quaker Center at Ben Lomond, California, for a weekend workshop, ?Social Fairness and Ecological Integrity: Strategy and Action for a Moral Economy.? This workshop was organized to launch the second phase of the Moral Economy Project of Quaker Institute for the Future. The first phase produced the book Right Relationship: Building a Whole Earth Economy. The workshop was co-sponsored by the Ecoberries affinity group of Strawberry Creek Monthly Meeting (Berkeley CA). George Lakey served as facilitator with Keith Helmuth, Phil Emmi, and Sandra Lewis as resource people and Shelley Tanenbaum as workshop coordinator. Advance materials sent to the registered participants?three background papers by Sandra Lewis, Phil Emmi, and Keith Helmuth?are included in this expanded version of this QEB