Antibacterial Resistance Leadership Group 2.0: Back to Business

In December 2019, the Antibacterial Resistance Leadership Group (ARLG) was awarded funding for another 7-year cycle to support a clinical research network on antibacterial resistance. ARLG 2.0 has 3 overarching research priorities: infections caused by antibiotic-resistant (AR) gram-negative bacteria, infections caused by AR gram-positive bacteria, and diagnostic tests to optimize use of antibiotics. To support the next generation of AR researchers, the ARLG offers 3 mentoring opportunities: the ARLG Fellowship, Early Stage Investigator seed grants, and the Trialists in Training Program. The purpose of this article is to update the scientific community on the progress made in the original funding period and to encourage submission of clinical research that addresses 1 or more of the research priority areas of ARLG 2.0

WHO global research priorities for antimicrobial resistance in human health

The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, and treatment of antimicrobial-resistant infections, in addition to addressing the overarching knowledge gaps in AMR epidemiology, burden and drivers, policies and regulations, and awareness and education. The research priorities were identified through a multistage process, starting with a comprehensive scoping review of knowledge gaps, with expert inputs gathered through a survey and open call. The priority setting involved a rigorous modified Child Health and Nutrition Research Initiative approach, ensuring global representation and applicability of the findings. The ultimate goal of this research agenda is to encourage research and investment in the generation of evidence to better understand AMR dynamics and facilitate policy translation for reducing the burden and consequences of AMR

A model of entrepreneurial activity with two actions over time and under uncertainty

Dynamic, Entrepreneur, Production technique, Search, Stochastic, L26, D81, D24,

Governance in democratic member-based organisations

This paper considers issues of governance in democratic memberbased organisations (DMOs), such as cooperatives and mutual societies. It examines the processes whereby members' interests are mediated through the democratic process, and the board; and it explores some of the factors influencing the power of managers. It goes on to argue that the system of governance in DMOs in their institutional context runs the risks of managers becoming powerful and entrenched in poorly performing social economy organisations, unless countervailing measures are adopted

Concepts of time and temporality in the storytelling and sensemaking literatures: a review and critique

A considerable body of literature exists on narratives and stories in explaining how individuals and groups make and give sense to their experiences in organizations. Classic Aristotelian narratives with a linear time structure (stories with a beginning, middle and end) are prominent in the storytelling literature, whereas retrospection, in drawing on the past in making sense of the present, is a temporal modality central to foundational concepts of sensemaking. In examining time and temporality in these related fields, the authors show how the conventional temporal sequence of a past, present and future dominates, with little consideration being given to time as a multiple rather than singular concept. The authors compare and contrast differences in the temporal aspects of mainstream theories and identify a growing interest in philosophical concepts of time. This review highlights how conventional explanations in these related fields of study are underpinned by linear conceptions of temporality (with an associated causality) and how there is growing recognition of fluidity in the way pasts and futures come together in temporal sensemaking of an emergent present. Although this movement towards explanations that engage with non‐linear modalities deepen insight, they do not explicitly address concepts of time. Time continues to receive scant attention, with temporal but ‘timeless’ theories taking precedence, ultimately constraining theoretical development. In building on this analysis, the authors characterize a range of temporal modalities from which they identify six pathways for charting out an agenda for future research in which multiple concepts of time and temporality are brought to the fore.Patrick Dawson and Christopher Syke