7. Recent Excavations on Prehistoric and Dynastic Sites in Egypt.

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Improving the clinical value and utility of CGM systems: issues and recommendations: a joint statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group

The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionize the use of intensive insulin therapy in diabetes; however, progress toward that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardized format for displaying results, and uncertainty on how best to use CGM data to make therapeutic decisions. This Scientific Statement makes recommendations for systemic improvements in clinical use and regulatory (pre- and postmarketing) handling of CGM devices. The aim is to improve safety and efficacy in order to support the advancement of the technology in achieving its potential to improve quality of life and health outcomes for more people with diabetes

Improving the clinical value and utility of CGM systems: issues and recommendations : a joint statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group

The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionise the use of intensive insulin therapy in diabetes; however, progress towards that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardised format for displaying results and uncertainty on how best to use CGM data to make therapeutic decisions. This scientific statement makes recommendations for systemic improvements in clinical use and regulatory (pre- and postmarketing) handling of CGM devices. The aim is to improve safety and efficacy in order to support the advancement of the technology in achieving its potential to improve quality of life and health outcomes for more people with diabetes

Three-dimensional analytical magnetohydrostatic equilibria of rigidly rotating magnetospheres in cylindrical geometry

We present three-dimensional solutions of the magnetohydrostatic equations in the co-rotating frame of reference outside a magnetized rigidly rotating cylinder. We make no symmetry assumption for the magnetic field, but to be able to make analytical progress we neglect outflows and specify a particular form for the current density. The magnetohydrostatic equations can then be reduced to a single linear partial differential equation for a pseudo-potential $U$, from which the magnetic field can be calculated by differentiation. The equation for $U$ can be solved by standard methods. The solutions can also be used to determine the plasma pressure, density and temperature as functions of all three spatial coordinates. Despite the obvious limitations of this approach, it can for example be used as a simple tool to create three-dimensional models for the closed field line regions of rotating magnetospheres without rotational symmetry.Comment: 13 pages, 2 figures, accepted for publication by Geophysical and Astrophysical Fluid Dynamic

Peripartum cardiomyopathy: diagnosis and management

No abstract available

Electricity supply industry modeling for multiple objectives under demand growth uncertainty

Appropriate energy–environment–economic (E3) modelling provides key information for policy makers in the electricity supply industry (ESI) faced with navigating a sustainable development path. Key challenges include engaging with stakeholder values and preferences, and exploring trade-offs between competing objectives in the face of underlying uncertainty. As a case study we represent the South African ESI using a partial equilibrium E3 modelling approach, and extend the approach to include multiple objectives under selected future uncertainties. This extension is achieved by assigning cost penalties to non-cost attributes to force the model's least-cost objective function to better satisfy non-cost criteria. This paper incorporates aspects of flexibility to demand growth uncertainty into each future expansion alternative by introducing stochastic programming with recourse into the model. Technology lead times are taken into account by the inclusion of a decision node along the time horizon where aspects of real options theory are considered within the planning process. Hedging in the recourse programming is automatically translated from being purely financial, to include the other attributes that the cost penalties represent. From a retrospective analysis of the cost penalties, the correct market signals, can be derived to meet policy goal, with due regard to demand uncertainty

Internalized and Anticipated Stigmatization in Patients With Gout

OBJECTIVE: To investigate the relationship between stigma perception and demographic, clinical, and psychosocial variables. METHODS: A sample of 50 patients with gout and prescribed urate‐lowering medication (84% were males, mean serum urate 0.34 mmol/l) completed questionnaires on internalized and anticipated stigma, demographics, clinical gout‐related variables, and psychosocial variables (illness perceptions, illness‐related disability, illness‐related body satisfaction, intentional nonadherence). Serum urate level was obtained from the most recent blood test. RESULTS: In this sample, 26% experienced internalized stigma, 26% expected to be stigmatized by friends or family members, and 14% by health care workers. Univariate regression analyses showed that younger age, ethnicity other than New Zealand European, increased severity of gout pain, cognitive and emotional illness perceptions, greater illness‐related disability, and increased intentional nonadherence to urate‐lowering medication were associated with increased internalized and anticipated stigma. Younger age, emotional illness response, and intentional nonadherence were the only variables explaining incremental variance of the experience of anticipated stigma in a multivariate regression model. CONCLUSION: Internalized and anticipated illness‐related stigma was reported by a subgroup of patients with gout. The experience of stigma is associated with younger age, a negative emotional illness response, and intentions to not adhere with a medical treatment

Ancient Egypt 1916 Part 3

Part 3 of the 1916 Ancient Egypt books. Contents include early forms of the cross, cutting granite, new portions of the annals, and the temple of Rameses, Abydos.https://knowledge.e.southern.edu/kweeks_coll/1007/thumbnail.jp

Magnetohydrostatic solar prominences in near-potential coronal magnetic fields

We present numerical magnetohydrostatic solutions describing the gravitationally stratified, bulk equilibrium of cool, dense prominence plasma embedded in a near-potential coronal field. These solutions are calculated using the FINESSE magnetohydrodynamics equilibrium solver and describe the morphologies of magnetic field distributions in and around prominences and the cool prominence plasma that these fields support. The equilibrium condition for this class of problem is usually different in distinct subdomains, separated by free boundaries, across which solutions are matched by suitable continuity or jump conditions describing force balance. We employ our precise finite element elliptic solver to calculate solutions not accessible by previous analytical techniques with temperature or entropy prescribed as free functions of the magnetic flux function, including a range of values of the polytropic index, temperature variations mainly across magnetic field lines and photospheric field profiles sheared close to the polarity inversion line. Out of the many examples computed here, perhaps the most noteworthy is one which reproduces precisely the three-part structure often encountered in observations: a cool dense prominence within a cavity/flux rope embedded in a hot corona. The stability properties of these new equilibria, which may be relevant to solar eruptions, can be determined in the form of a full resistive MHD spectrum using a companion hyperbolic stability solver.Comment: To appear in ApJ August 200

Altimetry, gravimetry, GPS and viscoelastic modeling data for the joint inversion for glacial isostatic adjustment in Antarctica (ESA STSE Project REGINA)

The poorly known correction for the ongoing deformation of the solid Earth caused by glacial isostatic adjustment (GIA) is a major uncertainty in determining the mass balance of the Antarctic ice sheet from measurements of satellite gravimetry and to a lesser extent satellite altimetry. In the past decade, much progress has been made in consistently modeling ice sheet and solid Earth interactions; however, forward-modeling solutions of GIA in Antarctica remain uncertain due to the sparsity of constraints on the ice sheet evolution, as well as the Earth's rheological properties. An alternative approach towards estimating GIA is the joint inversion of multiple satellite data – namely, satellite gravimetry, satellite altimetry and GPS, which reflect, with different sensitivities, trends in recent glacial changes and GIA. Crucial to the success of this approach is the accuracy of the space-geodetic data sets. Here, we present reprocessed rates of surface-ice elevation change (Envisat/Ice, Cloud,and land Elevation Satellite, ICESat; 2003–2009), gravity field change (Gravity Recovery and Climate Experiment, GRACE; 2003–2009) and bedrock uplift (GPS; 1995–2013). The data analysis is complemented by the forward modeling of viscoelastic response functions to disc load forcing, allowing us to relate GIA-induced surface displacements with gravity changes for different rheological parameters of the solid Earth. The data and modeling results presented here are available in the PANGAEA database (https://doi.org/10.1594/PANGAEA.875745). The data sets are the input streams for the joint inversion estimate of present-day ice-mass change and GIA, focusing on Antarctica. However, the methods, code and data provided in this paper can be used to solve other problems, such as volume balances of the Antarctic ice sheet, or can be applied to other geographical regions in the case of the viscoelastic response functions. This paper presents the first of two contributions summarizing the work carried out within a European Space Agency funded study: Regional glacial isostatic adjustment and CryoSat elevation rate corrections in Antarctica (REGINA)