Electronic Transport in 2D-Based Printed FETs from a Multiscale Perspective

The authors gratefully acknowledge the ERC PEP2D (contract no. 770047) and H2020 WASP (contract no. 825213) and the Crosslab Department of Excellence project for financial support. E.G.M. also acknowledges the support by the Spanish MCI through the project PID2020-116518GB-I00 and by the Junta de Andalucia-Consejeria de Economia y Conocimiento/FEDER-EU through the Project A-TIC-646-UGR20. Open access funding provided by Universita degli Studi di Pisa within the CRUI-CARE Agreement.As 2D materials (2DMs) gain the research limelight as a technological option for obtaining on-demand printed low-cost integrated circuits with reduced environmental impact, theoretical methods able to provide the necessary fabrication guidelines acquire fundamental importance. Here, a multiscale modeling technique is exploited to study electronic transport in devices consisting of a printed 2DM network of flakes. The approach implements a Monte Carlo scheme to generate the flake distribution. By means of ab initio density functional theory calculations together with non equilibrium Green’s functions formalism, detailed physical insights on flake-to-flake transport mechanisms are provided. This later feeds a 3D drift-diffusion and Poisson solution to compute self-consistently transport and electrostatics in the device. The method is applied to MoS2 and graphene-based dielectrically gated FETs, highlighting the impact of the structure density and variability on the mobility and sheet resistance. The prediction capability of the proposed approach is validated against electrical measurements of in-house printed graphene conductive lines as a function of film thickness, demonstrating its strong potential as a guide for future experimental activity in the field.ERC PEP2D 770047H2020 WASP 825213Crosslab Department of Excellence projectSpanish Government PID2020-116518GB-I00Junta de Andalucia-Consejeria de Economia y Conocimiento/FEDER-EU A-TIC-646-UGR20Universita degli Studi di Pisa within the CRUI-CARE Agreemen

Die überaktive Blase. Differenzialdiagnostik und therapeutisches Management

Die über- oder hyperaktive Blase kann die Befindlichkeit der Betroffenen erheblich stören. Abklärung und Therapie sollen patientinnenorientiert in verschiedenen Stufen erfolgen. Bei Therapieversagen trotz Verhaltensänderung, Blasentraining und Anticholinergika als primäre Therapien ist die intravesikale Injektion von Botulinumneurotoxin, aber auch Neuromodulation eine sehr wirksame Option. Neu erweitern β3-Adrenozeptor- Agonisten in Europa seit 2013* das therapeutische Spektrum

Removal of chlorinated pesticide contamination by soil washing with sole water

Chlorinated pesticide soil contamination still affects large territories due to past extensive use, poor solubility in water and scarce biodegradability of these agro-chemicals. In particular, this is noticeable for dichloro-diphenyl-trichloroethanes and their derivatives, globally referred as DDX contaminants. Presently, containment or immobilisation is a dominant approach to limit contamination, and remediation has been tried mainly at laboratory scale with contradictory results. Soil washing has been reported as a possible remediation treatment, although environmental effects of employed synthetic co-solvents or surfactants remain unclear. A soil washing treatment with sole water has been set up at laboratory scale, obtaining promising results on a contaminated soil with DDX level of 5050 mg/kg

Twelve months effect on voiding function of retropubic compared with outside-in and inside-out transobturator midurethral slings

Introduction and hypothesis: The purpose of this study is to compare retropubic tension-free vaginal tape (TVT) with transobturator out-in TOT and in-out TVT-O for female stress urinary incontinence. Uroflow rate was primary; continence rates, quality of life (QoL) and complication pattern were secondary endpoints. Methods: A prospective randomised trial with 2:1:1 randomisation at two Swiss teaching hospitals. Patients were followed up at 12months. Results: Eighty TVT, 40 transobturator tape (TOT) and 40 TVT-O were randomised. At 12months, there was no difference in Qmax among the groups. Continence was comparable (≥89%). QoL was improved significantly in all groups (P < 0.05). Five vaginal tape exposures occurred (one TVT, four TOT, zero TVT-O; P = 0.028). Two percent (1/52) of sexually active patients after TVT, 17% (5/29) after TOT, but 0% (0/25) after TVT-O reported de novo female sexual dysfunction (P = 0.011). We considered this clinically important enough to stop enrolment. Conclusions: There was no difference for Qmax at 12months between TVT, TOT and TVT-O. Female sexual dysfunction and tape exposure may be higher with a transobturator tap

L’hétérogénéité dans les classes :: comment gérer l’hétérogénéité culturelle et linguistique des élèves

Ce travail de mémoire repose essentiellement sur la gestion d’une classe ayant un grand niveau d’hétérogénéité (plus de 30%). En effet, de plus en plus d’étrangers vivent en Suisse et je me posais énormément de questions par rapport à leur intégration à l’école ; existe-t-il des ressources pour aider les enseignants ? Quelles activités, quels projets mettre en place pour intégrer les élèves allophones de la meilleure manière possible ? Comment cette multiculturalité s’est-elle développée en Suisse ? Des premières réponses à ces questions, ainsi que des informations autour du sujet de l’hétérogénéité dans les classes composent mon cadre théorique. Puis, mes analyses se basent sur les comportements d’une enseignante et les situations concrètes d’une classe que j’ai pu observer. Enfin, les apports de ce travail sur ma future pratique professionnelle, ainsi que de probables futures recherches en lien avec la multiculuturalité sont présentés dans ma conclusion

Patient satisfaction after retropubic and transobturator slings: first assessment using the Incontinence Outcome Questionnaire (IOQ)

Introduction and hypothesis: The aim of the Incontinence Outcome Questionnaire (IOQ) is to assess quality of life and patient-reported outcome after midurethral slings. Methods: In this retrospective study, 626 patients with a minimum follow-up period of 1year were sent the IOQ. Four hundred twenty-two of 626 (67.4%) patient responses were evaluated. Results: The mean IOQ QoL extended score was 33.7 ± 17.5 and comparable for tension-free vaginal tape (TVT), outside-in transobturator tape (TOT), and inside-out transobturator vaginal tape (TVT-O). Evaluation of IOQ question about readmission revealed a total of 32 patients (18 TVT, 12 TOT, and 2 TVT-O) who underwent a subsequent operation due to sling-related complications. Freedom from reoperation for recurrent SUI at 1, 2, and 5years was 100%, 99.7 ± 0.3%, and 99.7 ± 0.3% for TVT, 100% for TVT-O, and 94.2 ± 2.5%, 91.9 ± 2.9%, and 89.9 ± 3.5% for TOT, respectively (p < 0.001). Conclusions: Patient satisfaction, assessed using the IOQ, is high after retropubic and transobturator slings. In our collective, relapse incontinence is higher after TO

Histomorphological analysis of the urogenital diaphragm in elderly women: a cadaver study

The objective of this study was to describe the histomorphological structure of the urogenital diaphragm in elderly women using a modern morphometric procedure. Biopsies were taken from the posterior margin of the urogenital diaphragm of 22 female cadavers (mean age, 87years) using a 60-mm punch. Hematoxylin/eosin and Goldner sections were analyzed with the Cavalieri estimator. The mean thickness of the urogenital diaphragm was 5.5mm. The main component was connective tissue. All biopsies contained smooth muscle. Eighteen biopsies contained more smooth muscle than striated muscle. In six of 22 biopsies, no striated muscle was found. The ratio of striated to smooth muscle to connective tissue was 1:2.3:13.3. Muscle fibers were dispersed in all parts of the urogenital diaphragm. The urogenital diaphragm of elderly women mainly consists of connective tissue. Smooth muscle was also found but to a lesser extent. The frequently used English term "perineal membrane” for the urogenital diaphragm is justified and well describes our findings in elderly wome

Nr. 3: Die Behandlung bei Belastungsinkontinenz

Sobald die Diagnose Belastungsinkontinenz gesichert ist, kann diese heute mit etablierten Behandlungsmethoden erfolgreich angegangen werden. Im Folgenden werden konservative und chirurgische Massnahmen nach heutigem Goldstandard erläutert