Fishes of the Ohio River

Author Institution: Water Resources Laboratory, University of Louisville and Biology Department, Spalding UniversityTo date, 159 species of fishes (14 of them introduced by humans) have been reported from the Ohio River. Three native fishes {Acipenser fulvescens, Alosa alabamae, and Ammocrypta asprella) have apparently been eliminated from the river. The Ohio River fish community was severely affected by the siltation of clean gravel substrates, and the inundation of those substrates by the canalization of the river before 1927. In the past 20-30 years, populations of many species have increased, particularly in the upper third of the river. Some pollution-intolerant species which had disappeared from the upper reaches of the river between 1900 and 1950 have been returning since 1970 (e.g. Polyodon spathula, Hiodon tergisus, and Carpiodes velifer). A few pollution-tolerant species have declined in abundance since 1970 (e.g. bullheads and Ictalurus catus). The most abundant fishes in the lock chamber samples of 1957-87 were Notropis atherinoides, Dorosoma cepedianum, Aplodinotus grunniens, Notropis volucellus, and Ictalurus punctatus. The ongoing recovery of the Ohio River fish community should encourage us to take additional steps to protect the river from catastrophic spills of toxic materials and to reintroduce eliminated native fishes

Universal joint-measurement uncertainty relation for error bars

We formulate and prove a new, universally valid uncertainty relation for the necessary error bar widths in any approximate joint measurement of position and momentum

Using Proxies for the Short Rate: When are Three Months Like an Instant?

The dynamics of the unobservable "short" or "instantaneous" rate of interest are frequently estimated using a proxy variable. We show the biases resulting from this practice (the "proxy" problem) are related to the derivatives of the proxy with respect to the short rate and the (inverse) function from the proxy to the short rate. Analytic results show that the proxy problem is not economically significant for single- factor affine models, for parameter values consistent with US data. In addition, for the two-factor affine model of Longstaff and Schwartz (1992), the proxy problem is only economically significant for pricing discount bonds with maturities of more than 5 years. We also describe two different procedures which can be used to assess the magnitude of the proxy problem in more general interest rate models. Numerical evaluation of a nonlinear single-factor model suggests that the proxy problem can significantly affect both estimates of the diffusion function and discount bond prices.interest rates, proxies, term structure

A Comparison of Risk Exposure in Aquaculture and Agricultural Businesses

Agriculture and aquaculture have common features associated with their biological nature affecting risk exposure of the businesses. The aim of this paper is to compare risk exposure in salmon farming and agricultural enterprises in Norway by using an implicit error component model to examine the risk structure of yields, prices and economic returns at the farm level. Results indicate a higher farm-level year-to-year variability in yields, prices and economic returns in salmon farming than in agricultural enterprises. The variability in livestock enterprises was generally lower than for crop enterprises. Return on assets was highest in salmon farming with an average annual return of 9.2%. All of the agricultural farm types exhibited a negative average return on assets on average. Stochastic dominance tests of the distribution of economic returns from aquaculture and agricultural farm types showed salmon farming to be the most risk efficient alternative and salmon farming was most attractive from an investor’s perspective.Risk analysis, variability, Norway, Risk and Uncertainty,

Extracting quantum dynamics from genetic learning algorithms through principal control analysis

Genetic learning algorithms are widely used to control ultrafast optical pulse shapes for photo-induced quantum control of atoms and molecules. An unresolved issue is how to use the solutions found by these algorithms to learn about the system's quantum dynamics. We propose a simple method based on covariance analysis of the control space, which can reveal the degrees of freedom in the effective control Hamiltonian. We have applied this technique to stimulated Raman scattering in liquid methanol. A simple model of two-mode stimulated Raman scattering is consistent with the results.Comment: 4 pages, 5 figures. Presented at coherent control Ringberg conference 200

Turbulent separation upstream of a forward-facing step

The turbulent flow over a forward-facing step is studied using two-dimensional time-resolved particle image velocimetry. The structure and behaviour of the separation region in front of the step is investigated using conditional averages based on the area of reverse flow present. The relation between the position of the upstream separation and the two-dimensional shape of the separation region is presented. It is shown that when of ‘closed' form, the separation region can become unstable resulting in the ejection of fluid over the corner of the step. The separation region is shown to grow simultaneously in both the wall-normal and streamwise directions, to a point where the maximum extent of the upstream position of separation is limited by the accompanying transfer of mass over the step corner. The conditional averages are traced backwards in time to identify the average behaviour of the boundary-layer displacement thickness leading up to such events. It is shown that these ejections are preceded by the convection of low-velocity regions from upstream, resulting in a three-dimensional interaction within the separation region. The size of the low-velocity regions, and the time scale at which the separation region fluctuates, is shown to be consistent with the large boundary layer structures observed in the literature. Instances of a highly suppressed separation region are accompanied by a steady increase in velocity in the upstream boundary laye

A shrinking Compact Symmetric Object: J11584+2450?

We present multi-frequency multi-epoch Very Long Baseline Array (VLBA) observations of J11584+2450. These observations clearly show this source, previously classified as a core-jet, to be a compact symmetric object (CSO). Comparisons between these new data and data taken over the last 9 years shows the edge brightened hot spots retreating towards the core (and slightly to the west) at approximately 0.3c. Whether this motion is strictly apparent or actually physical in nature is discussed, as well as possible explanations, and what implications a physical contraction of J11584+2450 would have for current CSO models.Comment: 16 pages, 6 figures, 5 tables. Accepted for publication in Ap

Herschel-SPIRE-Fourier Transform Spectroscopy of the nearby spiral galaxy IC342

We present observations of the nearby spiral galaxy IC342 with the Herschel Spectral and Photometric Imaging Receiver (SPIRE) Fourier Transform Spectrometer. The spectral range afforded by SPIRE, 196-671 microns, allows us to access a number of 12CO lines from J=4--3 to J=13--12 with the highest J transitions observed for the first time. In addition we present measurements of 13CO, [CI] and [NII]. We use a radiative transfer code coupled with Bayesian likelihood analysis to model and constrain the temperature, density and column density of the gas. We find two 12CO components, one at 35 K and one at 400 K with CO column densities of 6.3x10^{17} cm^{-2} and 0.4x10^{17} cm^{-2} and CO gas masses of 1.26x10^{7} Msolar and 0.15x10^{7} Msolar, for the cold and warm components, respectively. The inclusion of the high-J 12CO line observations, indicate the existence of a much warmer gas component (~400 K) confirming earlier findings from H_{2} rotational line analysis from ISO and Spitzer. The mass of the warm gas is 10% of the cold gas, but it likely dominates the CO luminosity. In addition, we detect strong emission from [NII] 205microns and the {3}P_{1}->{3}P_{0} and {3}P_{2} ->{3}P_{1} [CI] lines at 370 and 608 microns, respectively. The measured 12CO line ratios can be explained by Photon-dominated region (PDR) models although additional heating by e.g. cosmic rays cannot be excluded. The measured [CI] line ratio together with the derived [C] column density of 2.1x10^{17} cm^{-2} and the fact that [CI] is weaker than CO emission in IC342 suggests that [CI] likely arises in a thin layer on the outside of the CO emitting molecular clouds consistent with PDRs playing an important role.Comment: 9 pages, 8 figures, accepted for publication in Monthly Notices of the Royal Astronomical Society (MNRAS

Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy

Adhesion to extracellular matrix (ECM) is crucially important for survival of normal epithelial cells as detachment from ECM triggers specific apoptosis known as anoikis. As tumor cells lose the requirement for anchorage to ECM, they rely on cell-cell adhesion 'multicellular aggregation' for survival. Multicellular aggregation of tumor cells also significantly determines the sensitivity of tumor cells to the cytotoxic effects of chemotherapeutics. In this report, we demonstrate that expression of immunoglobulin containing and proline-rich receptor-1 (IGPR-1) is upregulated in human primary colon cancer. Our study demonstrates that IGPR-1 promotes tumor multicellular aggregation, and interfering with its adhesive function inhibits multicellular aggregation and, increases cell death. IGPR-1 supports colon carcinoma tumor xenograft growth in mouse, and inhibiting its activity by shRNA or blocking antibody inhibits tumor growth. More importantly, IGPR-1 regulates sensitivity of tumor cells to the chemotherapeutic agent, doxorubicin/adriamycin by a mechanism that involves doxorubicin-induced AKT activation and phosphorylation of IGPR-1 at Ser220. Our findings offer novel insight into IGPR-1's role in colorectal tumor growth, tumor chemosensitivity, and as a possible novel anti-cancer target.Grant support from: R01 CA175382/CA/NCI NIH HHS/United States, R21 CA191970/CA/NCI NIH HHS/United States, and R21 CA193958/CA/NCI NIH HHS/United State