1,503 research outputs found

    Special cases of online parallel job scheduling

    Get PDF
    In this paper we consider the online scheduling of jobs, which require processing on a number of machines simultaneously. These jobs are presented to a decision maker one by one, where the next job becomes known as soon as the current job is scheduled. The objective is to minimize the makespan. For the problem with three machines we give a 2.8-competitive algorithm, improving upon the 3-competitive greedy algorithm. For the special case with arbitrary number of machines, where the jobs appear in non-increasing order of machine requirement, we give a 2.4815-competitive algorithm, improving the 2.75-competitive greedy algorithm

    Shunting passenger trains: getting ready for departure

    Get PDF
    In this paper we consider the problem of shunting train units on a railway station. Train units arrive at and depart from the station according to a given train schedule and in between the units may have to be stored at the station. The assignment of arriving to departing train units (called matching) and the scheduling of the movements to realize this matching is called shunting. The goal is to realize the shunting using a minimal number of shunt movements.\ud For a restricted version of this problem an ILP approach has been presented in the literature. In this paper, we consider the general shunting problem and derive a greedy heuristic approach and an exact solution method based on dynamic programming. Both methods are flexible in the sense that they allow the incorporation of practical planning rules and may be extended to cover additional requirements from practice

    Scenarios for an Energy Policy Concept of the German Government

    Get PDF
    In this working paper we demonstrate how challenging greenhouse gas reduction targets of up to 95% until 2050 can be achieved in the German electricity sector. In the analysis, we focus on the main requirements to reach such challenging targets. To account for interdependencies between the electricity market and the rest of the economy, different models were used to account for feedback loops with all other sectors. We include scenarios with different runtimes and retrofit costs for existing nuclear plants to determine the effects of a prolongation of nuclear power plants in Germany. Key findings for the electricity sector include the importance of a European-wide coordinated electricity grid extension and the exploitation of regional comparative cost effects for renewable sites. Due to political restrictions, nuclear energy will not be available in Germany in 2050. However, the nuclear life time extension has a positive impact on end consumer electricity prices as well as economic growth in the medium term, if retrofit costs do not exceed certain limits.Roadmap 2050; GHG reduction; renewable energies; carbon capture and storage; power plant fleet optimization

    CAIPI in Practice: Towards Explainable Interactive Medical Image Classification

    Full text link
    Would you trust physicians if they cannot explain their decisions to you? Medical diagnostics using machine learning gained enormously in importance within the last decade. However, without further enhancements many state-of-the-art machine learning methods are not suitable for medical application. The most important reasons are insufficient data set quality and the black-box behavior of machine learning algorithms such as Deep Learning models. Consequently, end-users cannot correct the model's decisions and the corresponding explanations. The latter is crucial for the trustworthiness of machine learning in the medical domain. The research field explainable interactive machine learning searches for methods that address both shortcomings. This paper extends the explainable and interactive CAIPI algorithm and provides an interface to simplify human-in-the-loop approaches for image classification. The interface enables the end-user (1) to investigate and (2) to correct the model's prediction and explanation, and (3) to influence the data set quality. After CAIPI optimization with only a single counterexample per iteration, the model achieves an accuracy of 97.48%97.48\% on the Medical MNIST and 95.02%95.02\% on the Fashion MNIST. This accuracy is approximately equal to state-of-the-art Deep Learning optimization procedures. Besides, CAIPI reduces the labeling effort by approximately 80%80\%.Comment: Manuscript accepted at IFIP AIAI 202

    Measurement of Individual Changes in the Performance of Human Stereoscopic Vision for Disparities at the Limits of the Zone of Comfortable Viewing

    Get PDF
    International audience3D displays enable immersive visual impressions but the impact on the human perception still is not fully understood. Viewing conditions like the convergence-accommodation (C-A) conflict have an unnatural influence on the visual system and might even lead to visual discomfort. As visual perception is individual we assumed the impact of simulated 3D content on the visual system to be as well. In this study we aimed to analyze the stereoscopic visual performance of 17 subjects for disparities inside and outside the in literature defined zone of comfortable viewing to provide an individual evaluation of the impact of increased disparities on the performance of the visual system. Stereoscopic stimuli were presented in a four-alternative forced choice (4AFC) setup in different disparities. The response times as well as the correct decision rates indicated the performance of stereoscopic vision. The results showed that increased disparities lead to a decline in performance. Further, the impact of the presented disparities is dependent on the difficulty of the task. The decline of performance as well as the deciding disparities for the decline were subject dependent

    Scenarios for an energy policy concept of the German government

    Full text link
    In this article we demonstrate how challenging greenhouse gas reduction targets of up to 95% until 2050 can be achieved in the German electricity sector.1 In the analysis, we focus on the main requirements to reach such challenging targets. To account for interdependencies between the electricity market and the rest of the economy, different models were used to account for feedback loops with all other sectors. We include scenarios with different runtimes and retrofit costs for existing nuclear plants to determine the effects of a prolongation of nuclear power plants in Germany. Key findings for the electricity sector include the importance of a European-wide coordinated electricity grid extension and the exploitation of regional comparative cost effects for renewable sites. Due to political restrictions, nuclear energy will not be available in Germany in 2050. However, the nuclear life time extension has a positive impact on end consumer electricity prices as well as economic growth in the medium term, if retrofit costs do not exceed certain limits

    Prevalence of iron deficiency and red blood cell transfusions in surgical patients

    Get PDF
    Background and Objectives  While iron deficiency (ID) is the most common cause of anaemia, little is known about the prevalence and type of ID in preoperative surgical patients. The aims of the present study were to investigate the prevalence and types of ID in a large cohort of surgical patients, and how these are related to perioperative blood use after correction for confounders such as haemoglobin level. Materials and Methods Data were retrospectively extracted from electronic case records of all patients who underwent elective surgery between September 2016 and November 2017 (n = 2711). Iron parameters, haemoglobin and details of perioperative red cell transfusions were collected. Results Of 2711 patients, 618 (22.8%) were iron deficient (= transferrin saturation [TSAT] = 30 mu g/L). Corrected for Hb level, iron-deficient patients received significantly more red cell units than patients without ID (p = 0.026). AID was not associated with a significantly higher incidence of transfusions (7.5% of patients transfused; p = 0.12 after correction for Hb) than patients without ID, whereas patients with functional/mixed deficiency did receive significantly more transfusions (6.1%; p = 0.021) as compared to patients without ID (1.7%). Conclusion Preoperative ID, in particular the functional/mixed type, was associated with a higher risk of receiving perioperative red cell transfusions as compared to patients without ID. Adequately treating ID might, therefore, reduce the need for perioperative red cell transfusions

    Phospholenes from Phosphabenzenes by Selective Ring Contraction

    Get PDF
    A 3-aminofunctionalized phosphabenzene (phosphinine) was synthesized and structurally characterized. The pyramidalized nitrogen atom of the dimethylamino substituent indicates only a weak interaction between the lone pair of the nitrogen atom and the aromatic phosphorus heterocycle, resulting in somewhat basic character. It turned out that the amino group can indeed be protonated by HCl. In contrast to pyridines, however, the phosphabenzene-ammonium salt undergoes a selective ring contraction to form a hydroxylphospholene oxide in the presence of additional water. Based on deuterium labelling experiments and quantum chemical calculations, a rational mechanism for this hitherto unknown conversion is proposed

    The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest

    Get PDF
    Introduction Patients after out-of-hospital cardiac arrest (OHCA) benefit from therapeutic hypothermia for 24 hours. The time needed to reach hypothermia (target temperature of 32 degrees C to 34 degrees C) varies widely. In this study, we explore the relation between measures of body composition and the time needed to reach target temperature with hypothermia. Method We conducted a prospective observational study in patients treated with hypothermia after OHCA. Data collected included weight and height, body composition by anthropometric measures and by single-frequency body impedance, and waist-to-hip ratio. Analysis of concordance between impedance and anthropometric measures and hazard ratios of achieving target temperature (event) corrected for different body composition measures. Results Twenty-seven patients were included. The median (interquartile range) time to reach target temperature after admission to the intensive care unit was 191 (105 to 382) minutes. Intraclass correlation for total body fat (TBF) measures was 0.94 (95% confidence interval [CI] 0.89 to 0.97). Only TBF percentage (anthropometrics by the Durnin's table) appeared to be associated with time to reach target temperature: 0.93 (95% CI 0.87 to 0.99; P = 0.03). Conclusion The body composition measures from single-frequency impedance and anthropometrics appear to be very concordant. Only TBF percentage (anthropometrics) showed a significant but clinically irrelevant influence on time needed to achieve target temperature with hypothermia. We conclude that there are no indications to adjust current cooling practice toward the body composition of patient
    corecore