Novos materiais híbridos a base de ZnAl2O4 dopados com európio.

Nanopartículas de ZnAl1,9Eu0,1O4 foram modificadas a superfície usando agentes amino-silanos, e funcionalizadas a partir de monômeros do tipo metilmetacrilato, etilenodiamina e quitosana como moléculas biocompatíveis. As nanopartículas do ZnAl1,9Eu0,1O4 foram obtidas por reação de combustão, e silanizadas com os agentes silanos 3 – aminopropiltrimetoxisilano e 3 – aminopropiltrietoxisilano, com o intuito de tornar o caráter do espinélio hidrofóbico e em seguida funcionalizadas. As amostras resultantes foram caracterizadas por Difração de raios X, Espectroscopia de Infra Vermelho com Transformada de Fourrier, Microscopia Eletrônica de Transmissão, Espectroscopia de Excitação e Emissão e Rendimento quântico. Os resultados revelaram a formação da fase cúbica ZnAl1,9Eu0,1O4 e traços de EuAlO3. Para as amostras funcionalizadas com quitosana observa-se a formação da fase espinélio e da fase quitosana. Mediante os espectros de FTIR observou-se bandas abaixo de 1000 cm-1 atribuídas às vibrações dos sítios tetraédricos e octaédricos. As amostras funcionalizadas com quitosana apresentaram melhor complexação (interação óxido /polímero) e presença de estiramento NH atribuído ao grupo NH2 da quitosana. A banda de C=O observada para o espinélio ZnAl1,9Eu0,1O4 com quitosana evidenciou a funcionalização das nanopartículas. As nanopartículas ZnAl1,9Eu0,1O4 apresentaram morfologia constituída de aglomerados com formato de agulhas, constituídos de partículas com formato aproximadamente hexagonal, e tamanho menores que 100 nm. Após funcionalização as nanopartículas ZnAl1,9Eu0,1O4 apresentaram morfologia não homogênea, composta por um filme e partículas impregnadas de formato aproximadamente esférica, contendo fases amorfas e cristalinas, com partículas menores que 100 nm. As amostras silanizadas, funcionalizadas com os monômeros e a amostra funcionalizada com quitosana na proporção 5:1, apresentaram as linhas espectrais do íon Eu3+ correspondentes as transições 5D0 → 7F0, 5D0 → 7F1, 5D0 → 7F2, 5D0 → 7F3 e 5D0 → 7F4. O maior rendimento quântico foi observado para a amostra funcionalizada com a mistura dos monômeros utilizando o 3- aminopropiltrimetoxisilano.Nanoparticles ZnAl1,9Eu0,1O4 were surface modified using amino-silane agents, and from functionalized monomers like methylmethacrylate, ethylenediamine and chitosan as biocompatible molecules. Nanoparticles of ZnAl1,9Eu0,1O4 were obtained by combustion reaction, and silanized with silane agents and 3- aminopropyltrimethoxysilane and 3 -aminopropyltriethoxysilane, in order to make the hydrophobic character of the spinel and then functionalized. The resulting samples were characterized by X-ray Diffraction, Infrared Spectroscopy Fourier Transform, Transmission Electron Microscopy, Excitation and Emission Spectroscopy and quantum yield. The results revealed the formation of cubic phase ZnAl1,9Eu0,1O4 and traces of EuAlO3. For samples functionalized with chitosan, we observed the formation of spinel phase and phase chitosan. Through the FTIR spectra observed bands below 1000 cm-1 assigned to the vibrations of tetrahedral and octahedral sites. The samples functionalized with chitosan showed better complexation (interaction oxide / polymer) and the presence of NH stretch assigned to NH2 group of chitosan. C = O band observed for the spinel ZnAl1,9Eu0,1O4 with chitosan showed the functionalization of nanoparticles. Nanoparticles ZnAl1,9Eu0,1O4 showed morphology composed of needle-shaped clusters consisting of particles with roughly hexagonal shape, and size smaller than 100 nm. Nanoparticles ZnAl1,9Eu0,1O4 after functionalization showed inhomogeneous morphology, consisting of a film and impregnated particles of roughly spherical shape containing amorphous and crystalline phases, with particles smaller than 100 nm. The silanized samples, functionalized with monomers functionalized with chitosan and the sample in 5:1 ratio showed the spectral lines corresponding Eu3+ ion transitions 5D0 → 7F0, 7F1 → 5D0, 5D0 → 7F2, 5D0 → 7F3 and 5D0 → 7F4. The higher quantum yield observed for the sample was functionalized with a mixture of monomers using the 3-aminopropyltrimethoxysilane.Cape

Reporting an experience : recovering and recording residues of teaching laboratories of Chemical Institute of the Federal University of Rio Grande do Sul.

An experience aiming to promote a residue interchange and recovery between the teaching laboratories of the Chemistry Institute of this University is described. At the present, several residues interchange have already appeared as advantageous. To make the work easier, a software has been developed in order to keep a record of all the residues generated by the teaching laboratories. Standard labels have been developed for the residues in order to organize them. The software and the label design are described

Concepções teóricas e metodológicas do cuidado transdisciplinar: uma revisão integrativa

Introdução: Objetivou-se realizar um levantamento da produção científica na enfermagem e suas interfaces sobre as concepções teóricas e metodológicas do cuidado e discutir o cuidado na enfermagem e suas interfaces na perspectiva da complexidade em atitude transdisciplinar.Métodos: Trata-se de uma revisão integrativa que utilizou o Portal de Periódicos da CAPES, no período entre 2005 e 2015

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Neuroproteção na ressecção cirúrgica de gliomas cerebrais: revisão da evidência atual

Os gliomas cerebrais são tumores primários do sistema nervoso central que se desenvolvem a partir de células gliais e têm alta morbimortalidade. Seu tratamento padrão envolve a ressecção cirúrgica, radioterapia e quimioterapia, os quais possivelmente podem levar os pacientes a um prognóstico desfavorável. Nesse contexto, a neuroproteção entra como uma aliada para minimizar os efeitos colaterais da ressecção cirúrgica e melhorar a sobrevida e a qualidade de vida dos pacientes. Nesse sentido, o presente estudo tem como objetivo discutir sobre a evidência atual da neuroproteção na ressecção cirúrgica de gliomas cerebrais. Para isso, foram selecionados quatro artigos que que abordavam sobre a evidência atual da neuroproteção na ressecção cirúrgica de gliomas cerebrais, por meio de uma estratégia de busca com recorte temporal entre 2014 e 2023, nas bases de dados PubMed (Medline), Embase e Cochrane Library. Os resultados indicam que o grupo de pacientes que recebeu dexmedetomidina apresentou melhora significativa na cognição e redução da inflamação cerebral em comparação com o grupo-controle pós-ressecção dos gliomas cerebrais, além de menor incidência de efeitos colaterais anestésicos, como náusea e vômitos (p < 0,05). Ademais, foi observado que a modulação da via metabólica do glutamato/glutamina pode inibir o crescimento de gliomas e proteger o parênquima cerebral. Nesse sentido, as evidências atuais indicam que proteger as células nervosas é uma estratégia importante para minimizar os efeitos colaterais da ressecção cirúrgica de gliomas cerebrais, e a dexmedetomidina e a co-cultura de células de glioma e astrócitos que aumenta a concentração extracelular de glutamato e glutamina parecem ser importantes aliadas nessa profilaxia

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost