Lepton Flavour Violation in a Left-Right Symmetric Model

We consider in this paper a Left-Right symmetric gauge model in which a global lepton-number-like symmetry is introduced and broken spontaneously at a scale that could be as low as 10^4 GeV or so. The corresponding physical Nambu-Goldstone boson, which we call majoron and denote J, can have tree-level flavour-violating couplings to the charged fermions, leading to sizeable majoron-emitting lepton-flavour-violating weak decays. We consider explicitly a leptonic variant of the model and show that the branching ratios for \mu -> e+J, \tau -> e + J and \tau -> \mu + J decays can be large enough to fall within the sensitivities of future \mu and \tau factories. On the other hand the left-right gauge symmetry breaking scale may be as low as few TeV.Comment: LaTeX, 16 pages, 3 PS figures, uses JHEP.cls, published versio

Low-energy solar anti-neutrinos

If neutrino conversions within the Sun result in partial polarization of initial solar neutrino fluxes, then a new opportunity arises to observe the anti-\nu_e's in future neutrino experiments in the low energy region (such as BOREXINO or HELLAZ) and thus to probe the Majorana nature of the neutrinos. The \nu_e -> anti-\nu_e conversions may take place for low energy solar neutrinos while being unobservable at the Kamiokande and Super-Kamiokande experiments.Comment: Talk given at TAUP 97, Gran Sasso, Italy, Sep. 1997; LaTeX, 3 pages, 1 postscript figure, uses espcrc2.st

A potential test of the CP properties and Majorana nature of neutrinos

The scattering of solar neutrinos on electrons may reveal their CP properties, which are particularly sensitive to their Majorana nature. The cross section is sensitive to the neutrino dipole moments through an interference of electro-magnetic and weak amplitudes. We show how future solar neutrino experiments with good angular resolution and low energy threshold, such as Hellaz, can be sensitive to the resulting azimuthal asymmetries in event number, and could therefore provide valuable information on the CP properties and the nature of the neutrinos, provided the solar magnetic field direction is fixed.Comment: 14 pages, 1 figure, eq. (19) corrected. Version to be publishe

A White Paper on keV sterile neutrino Dark Matter

We present a comprehensive review of keV-scale sterile neutrino Dark Matter, collecting views and insights from all disciplines involved - cosmology, astrophysics, nuclear, and particle physics - in each case viewed from both theoretical and experimental/observational perspectives. After reviewing the role of active neutrinos in particle physics, astrophysics, and cosmology, we focus on sterile neutrinos in the context of the Dark Matter puzzle. Here, we first review the physics motivation for sterile neutrino Dark Matter, based on challenges and tensions in purely cold Dark Matter scenarios. We then round out the discussion by critically summarizing all known constraints on sterile neutrino Dark Matter arising from astrophysical observations, laboratory experiments, and theoretical considerations. In this context, we provide a balanced discourse on the possibly positive signal from X-ray observations. Another focus of the paper concerns the construction of particle physics models, aiming to explain how sterile neutrinos of keV-scale masses could arise in concrete settings beyond the Standard Model of elementary particle physics. The paper ends with an extensive review of current and future astrophysical and laboratory searches, highlighting new ideas and their experimental challenges, as well as future perspectives for the discovery of sterile neutrinos

Low-energy Anti-neutrinos from the Sun

We consider the sensitivity of future neutrino experiments in the low energy region, such as BOREXINO or HELLAZ, to a solar electron antineutrino signal. We show that, if neutrino conversions within the Sun result in partial polarization of initial solar neutrino fluxes, then a new opportunity arises to observe the electron antineutrinos and thus to probe the Majorana nature of the neutrinos. This is achieved by comparing the slopes of the energy dependence of the differential neutrino electron scattering cross section for different neutrino conversion scenarios. We also show how the \nu_e -> \bar{\nu}_e conversions may take place for low energy solar neutrinos while being unobservable at the Kamiokande and Super-Kamiokande experiments.Comment: LaTeX, 14 pages, 3 PS figures included, 3 references adde

Primordial nucleosynthesis, majorons and heavy tau neutrinos

We determine the restrictions imposed by primordial nucleosynthesis upon a heavy tau neutrino, in the presence of nu-tau annihilations into Majorons, as expected in a wide class of particle physics models of neutrino mass. We determine the equivalent number of light neutrino species Neq as a function of nu-tau mass and the nu-tau-Majoron coupling g. We show that for theoretically plausible g values \gsim 10^{-4} present nucleosynthesis observations can not rule out nu-tau masses in the MeV range. Moreover, these models give Neq≤3 in the nu-tau mass region 1-10 MeV, for very reasonable values of g≥3×10−4. The evasion of the cosmological limits brings new interest to the improvement of the present laboratory limit on the nu-tau mass which can be achieved at a tau-charm factory

Protein delivery based on uncoated and chitosan-coated mesoporous silicon microparticles

Mesoporous silicon is a biocompatible, biodegradable material that is receiving increased attention for pharmaceutical applications due to its extensive specific surface. This feature enables to load a variety of drugs in mesoporous silicon devices by simple adsorption-based procedures. In this work, we have addressed the fabrication and characterization of two new mesoporous silicon devices prepared by electrochemistry and intended for protein delivery, namely: (i) mesoporous silicon microparticles and (ii) chitosan-coated mesoporous silicon microparticles. Both carriers were investigated for their capacity to load a therapeutic protein (insulin) and a model antigen (bovine serum albumin) by adsorption. Our results show that mesoporous silicon microparticles prepared by electrochemical methods present moderate affinity for insulin and high affinity for albumin. However, mesoporous silicon presents an extensive capacity to load both proteins, leading to systems were protein could represent the major mass fraction of the formulation. The possibility to form a chitosan coating on the microparticles surface was confirmed both qualitatively by atomic force microscopy and quantitatively by a colorimetric method. Mesoporous silicon microparticles with mean pore size of 35 nm released the loaded insulin quickly, but not instantaneously. This profile could be slowed to a certain extent by the chitosan coating modification. With their high protein loading, their capacity to provide a controlled release of insulin over a period of 60-90 min, and the potential mucoadhesive effect of the chitosan coating, these composite devices comprise several features that render them interesting candidates as transmucosal protein delivery systems