A Self-Service Supporting Business Intelligence and Big Data Analytics Architecture

Self-service Business Intelligence (SSBI) is an emerging topic for many companies. Casual users should be enabled to independently build their own analyses and reports. This accelerates and simplifies the decision-making processes. Although recent studies began to discuss parts of a self-service environment, none of these present a comprehensive architecture. Following a design science research approach, this study proposes a new self-service oriented BI architecture in order to address this gap. Starting from an in-depth literature review, an initial model was developed and improved by qualitative data analysis from interviews with 18 BI and IT specialists form companies across different industries. The proposed architecture model demonstrates the interaction between introduced self-service elements with each other and with traditional BI components. For example, we look at the integration of collaboration rooms and a self-learning knowledge database that aims to be a source for a report recommender

Salt intake induces epithelial-to-mesenchymal transition of the peritoneal membrane in rats

Methods. Twenty-eight Wistar rats were randomized to a normal salt (NS) or a high salt (HS) intake. NS and HS rats had free access to tap water or NaCl 2% as drinking water, respectively. After 2 weeks, samples of peritoneum were taken, and TGF-beta(1), Interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) mRNA expression were quantified with qRT-PCR. Fibrosis and submesothelial PM thickness were scored. EMT was evaluated using fluorescence staining with cytokeratin and alpha smooth muscle actin (alpha-SMA). Results. Dietary salt intake caused peritoneal fibrosis and thickening of the submesothelial layer and induced EMT as identified by colocalization of cytokeratin and alpha-SMA in cells present in the submesothelial layer. Peritoneal TGF-beta(1) and IL-6 mRNA expression were upregulated in the HS group. Conclusion. High dietary salt intake induces EMT and peritoneal fibrosis, a process coinciding with upregulation of TGF-beta 1

Legal and Privacy Concerns of BYOD Adoption

We investigate legal concerns in privacy calculus, which are currently not given enough attention in privacy research. Legal aspects can lead to liability issues in various information systems scenarios such as bring your own device (BYOD) in the workplace. To analyze the impact of legal concerns in privacy calculus, we conducted a quantitative study by surveying 542 employees from three countries: United States, Germany, and South Korea. Building on our research model to test our hypothesized relationships, structural equation modeling was employed. Our findings provide recommendations for multinational organizations to mitigate legal concerns in privacy calculus. A comparison of the three countries reveals that employees from the United States and South Korea place greater emphasis on legal concerns compared to German employees. We develop an understanding of employees’ concerns with liability issues, and how these affect their privacy calculus in a BYOD context

Self-service business intelligence and analytics application scenarios: A taxonomy for differentiation

Self-service business intelligence and analytics (SSBIA) empowers non-IT users to create reports and analyses independently. SSBIA methods and processes are discussed in the context of an increasing number of application scenarios. However, previous research on SSBIA has made distinctions among these scenarios only to a limited extent. These scenarios include a wide variety of activities ranging from simple data retrieval to the application of complex algorithms and methods of analysis. The question of which dimensions are suitable for differentiating SSBIA application scenarios remains unanswered. In this article, we develop a taxonomy to distinguish among SSBIA applications more effectively by analyzing the relevant scientific literature and current SSBIA tools as well as by conducting a case study in a company. Both researchers and practitioners can use this taxonomy to describe and analyze SSBIA scenarios in further detail. In this way, the opportunities and challenges associated with SSBIA application can be identified more clearly. In addition, we conduct a cluster analysis based on the SSBIA tools thus analyzed. We identify three archetypes that describe typical SSBIA tools. These archetypes identify the application scenarios that are addressed most frequently by SSBIA tool providers. We conclude by highlighting the limitations of this research and suggesting an agenda for future research

Virtual Assistance in Any Context: A Taxonomy of Design Elements for Domain-Specific Chatbots

Several domain-specific assistants in the form of chatbots have conquered many commercial and private areas. However, there is still a limited level of systematic knowledge of the distinctive characteristics of design elements for chatbots to facilitate development, adoption, implementation, and further research. To close this gap, the paper outlines a taxonomy of design elements for chatbots with 17 dimensions organized into the perspectives intelligence, interaction and context. The conceptually grounded design elements of the taxonomy are used to analyze 103 chatbots from 23 different application domains. Through a clustering-based approach, five chatbot archetypes that currently exist for domain-specific chatbots are identified. The developed taxonomy provides a structure to differentiate and categorize domain-specific chatbots according to archetypal qualities that guide practitioners when taking design decisions. Moreover, the taxonomy serves academics as a foundation for conducting further research on chatbot design while integrating scientific and practical knowledge

How to Make chatbots productive – A user-oriented implementation framework

Many organizations are pursuing the implementation of chatbots to enable automation of service processes. However, previous research has highlighted the existence of practical setbacks in the implementation of chatbots in corporate environments. To gain practical insights on the issues related to the implementation processes from several perspectives and stages of deployment, we conducted semi-structured interviews with developers and experts of chatbot development. Using qualitative content analysis and based on a review of literature on human computer interaction (HCI), information systems (IS), and chatbots, we present an implementation framework that supports the successful deployment of chatbots and discuss the implementation of chatbots through a user-oriented lens. The proposed framework contains 101 guiding questions to support chatbot implementation in an eight-step process. The questions are structured according to the people, activity, context, and technology (PACT) framework. The adapted PACT framework is evaluated through expert interviews and a focus group discussion (FGD) and is further applied in a case study. The framework can be seen as a bridge between science and practice that serves as a notional structure for practitioners to introduce a chatbot in a structured and user-oriented manner

The effect of pH-neutral peritoneal dialysis fluids on adipokine secretion from cultured adipocytes

Background. Adipokines are a group of fat-secreted hormones and cytokines, including leptin and adiponectin, with important functions in humans. Peritoneal dialysis (PD) is associated with markedly raised plasma adipokines, suggesting increased production in this setting. We have shown that low pH down-regulates leptin production. The current study was designed to test if novel pH-neutral PD fluids may regulate leptin and adiponectin secretion in vitro. Methods. We exposed 3T3-L1 adipocytes to a 50 : 50 mixture of dialysate and M199 containing 10% serum for upto 48 h. Dialysates were commercial PD fluids, i.e. conventional acidic, lactate-buffered solutions (PD-acid) and pH-neutral lactate-buffered (PD-Bal) or bicarbonate-buffered solutions (PD-Bic). Leptin and adiponectin concentrations in culture-cell media were measured by ELISA. Results. Compared with PD-acid, PD-Bal and PD-Bic produced a 25 and 43% increase, respectively, in leptin secretion at 48 h (P < 0.05). In contrast, adiponectin secretion was not affected. High glucose PD fluids (4.25%) specifically inhibited leptin secretion vs 1.5% glucose, buffer-matched solutions (P < 0.05). However, differences in leptin secretion due to pH and type of buffer remained significant. In further experiments, the pH of test media were extensively varied without the presence of dialysates. Leptin secretion was shown to increase in a parallel to pH, whereas large changes in pH did not affect adiponectin secretion. Conclusion. The pH-neutral PD solutions specifically induce leptin, but not adiponectin secretion from 3T3-L1 adipocytes. PD-Bic produced a greater leptin stimulation than PD-Bal, but this difference was attributable to pH per se, rather than the type of buffe

Should hepatomas be treated with hepatic resection or transplantation?

BACKGROUND: The aim of this collaborative study was to compare the long term results of hepatic resection (Hx) with those of orthotopic liver transplantation (OLTx) in large numbers of cirrhotic patients with hepatocellular carcinoma (HCC) and to delineate the roles of these two surgical treatments. METHODS: The databases of the National Cancer Center Hospital in Japan and the University of Pittsburgh Medical Center in the U. S. were exchanged and 294 cirrhotic patients who underwent curative Hx and 270 cirrhotic patients who underwent curative OLTx were selected for comparison. RESULTS: The mortality rate within 30 days and that within 150 days after Hx were significantly lower than those after OLTx (P = 0.001 and P = 0.00007, respectively). Overall survival was similar between the Hx group and the OLTx group (P = 0.40). When compared in the HCC patients without macroscopic vascular invasion and lymph node metastases, the overall survival rate after OLTx was significantly higher than that after Hx (P = 0.006). However, this difference was not significant between the patients with Child-Pugh Grade A tumors in the Hx group and all patients (majority with Child-Pugh Grade C tumors) in the OLTx group (P = 0.25). Tumor free survival after OLTx was significantly higher than that after Hx (P 5 cm and those with macroscopic vascular invasion, the tumor free survival rate was similar between the Hx group and the OLTx group. CONCLUSIONS: In the face of organ shortage, HCC developing in a well compensated cirrhotic liver initially may be treated with Hx. However, the authors believe OLTx should be applied selectively to those patients with tumor recurrence and/or progressive hepatic failure

Future of Flexible Work in the Digital Age: Bring Your Own Device Challenges of Privacy Protection

The future of work is getting increasingly flexible due to the rising expectations of employees away from traditional 9-to-5 office work towards flexible work hours, which drives employees to use their mobile devices for work. This ever-growing phenomenon of Bring Your Own Device (BYOD) creates security risks for companies, which leads to an implementation of mobile device management (MDM) solutions to secure and monitor employees’ mobile devices. We present insights from two multinational case companies, where works councils have expressed their concerns for privacy intrusion into employees’ lives through BYOD. To examine whether employees share works councils’ concerns, we conducted a survey with 542 employees from three countries: United States, Germany, and South Korea. Results of a structural equation modeling show that American employees place greater emphasis on BYOD risks associated with privacy concerns compared to employees from Germany and South Korea

Laboratory and dialysis characteristics in hemodialysis patients suffering from chronic itch - results from a representative cross-sectional study

Background: A representative cross-sectional study showed that chronic itch (lasting for a minimum of 6 weeks) affects 25.2 % (point prevalence) of hemodialysis (HD) patients. Pathophysiology and etiology of chronic itch (CI) in HD are still unclear. Methods: We investigated 860 HD patients from a representative randomly selected cluster-sample considering the regional distributions of dialysis units in GermanyThe current analyses report comorbidities, laboratory values and dialysis characteristics of HD patients in relation to CI. Results: Diabetes was the only comorbidity that was associated with the occurrence of itch but interestingly with less CI. Except for creatinine, phosphorus, and parathormone, there were no significant associations between the occurrence and characteristics of CI and any laboratory value. Kt/V was not associated with the presence of CI. Patients dialyzed with polyarylethersulfone-membrane showed significantly more CI in all prevalence estimates and those dialyzed with polysulfone-membrane were significantly less affected by CI. Conclusions: Long-term follow-up studies will show if the type of dialysis membrane influences the development of CI in HD patients. It is most likely that several factors e.g. elevated parathormone, origin of end stage renal disease (ESRD), type of dialysis membrane, and a neuropathic component all contribute to the occurrence of CI in HD patients. Future research should consider a multifactorial origin of itch in HD