10 research outputs found

    Social Design. Design e bene comune.

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    Per questo primo doppio numero della rivista, Social Design. Design e "bene comune", curato da Marinella Ferrara, Francesco E. Guida, Mario Piazza, Paola Proverbio e Raimonda Riccini, quasi come una sfida, si è provato a rompere l’ortodossia di un approccio lineare alla storia. In questo orientamento, che tende a portare più vicino a noi i temi storici, il Social Design si offre in modo calzante per il suo essere questione contemporanea e complessa, ampia e ambigua financo controversa, anche solo dal punto di vista delle diverse espressioni sinonimiche con cui si presenta: design etico, design umanitario, design per la collettività, design di pubblica utilità, design per l’utenza ampliata, design per la sostenibilità, ... Il numero ha ricevuto la Menzione d'Onore alla XXVII edizione del Compasso d'Oro (giugno 2022), ed è stato segnalato nell'ADI Design Index 2021 (promosso da ADI, Associazione per il Disegno Industriale) nella sezione "Ricerca teorica, storica, critica e progetti editoriali"

    Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

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    Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening

    Captioned and Nonverbal Films for the Hearing-Impaired

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    Arresti domiciliari ed esigenze spirituali dell’imputato, a proposito di una recente sentenza

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    New and forthcoming reference books from Gale Research company

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    Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

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    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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