Incidence and clinicopathologic behavior of uterine cervical carcinoma in renal transplant recipients

<p>Abstract</p> <p>Background</p> <p>Renal allograft recipients are reported to have a higher incidence of malignancy than the general population. This single hospital-based study examined the incidence and clinicopathologic behavior of uterine cervical carcinoma in renal transplant recipients.</p> <p>Methods</p> <p>Among 453 women receiving renal transplantation from January 1990 to December 2008, 5 patients were diagnosed with cervical carcinoma. Medical records of these 5 patients were retrospectively reviewed, and clinicopathologic data were collected and analyzed.</p> <p>Results</p> <p>The incidence of cervical carcinoma in renal transplant recipients was 58.1 out of 100,000 per year, which is 3.5 times higher than in the general Korean population. The mean interval between the time of renal transplantation and the time of cervical carcinoma diagnosis was 80.7 months. After a median follow-up of 96.2 months, there was no recurrence of the disease or death. In 4 patients who were positive from human papillomavirus in situ hybridization (HPV ISH), high or probably high risk HPV DNA was detected in all. Punctate staining of HPV ISH was detected in 3 out of 4 patients.</p> <p>Conclusions</p> <p>Higher incidence of cervical carcinoma is expected in renal transplant recipients, so appropriate surveillance is needed to ensure early detection and treatment of cervical carcinoma.</p

What Questions do People Ask on a Human Papillomavirus Website? A Comparative Analysis of Public and Private Questions

Objective: In 2004, we launched the question and answer (Q&A) section on a human papillomavirus (HPV) website (www.hpvkorea.org) that provides ample and regularly updated information about HPV. The purpose of this study is to collect data pertaining to questions posed on this website about HPV and its related diseases and analyze the type of questions and frequency before and after introduction of HPV vaccine in Korea. Using these results, we intend to determine the clinical and practical implications for doctors treating HPV and for HPV website providers

Flexural Behavior of Concrete Beam Strengthened by Near-Surface Mounted CFRP Reinforcement Using Equivalent Section Model

FRP (fiber reinforced polymer) has found wide applications as an alternative to steel rebar not only for the repair and strengthening of existing structures but also for the erection of new structures. Near-surface mounted (NSM) strengthening was introduced as an alternative of externally bonded reinforcement (EBR) but this method also experiences early bond failure, which stresses the importance of predicting accurately the bond failure behavior in order to evaluate precisely the performance of NSM reinforcement. This study proposes the equivalent section model assuming monolithic behavior of the filler and CFRP reinforcement. This equivalent section model enables establishing a bond failure model applicable independently of the sectional shape of the CFRP reinforcement. This so-derived bond failure model is then validated experimentally by means of beams flexure-strengthened by NSM CFRP reinforcements with various cross-sections. Finally, analytical analysis applying the bond failure model considering the equivalent section and defined failure criteria is performed. The results show the accuracy of the prediction of the failure mode as well as the accurate prediction of the experimental results regardless of the sectional shape of the CFRP reinforcement

Flexural Behaviour of RC Beams Strengthened with Prestressed CFRP NSM Tendon Using New Prestressing System

CFRP has been used mainly for strengthening of existing structures in civil engineering area. Prestressed strengthening is being studied to solve the bond failure model featuring EBR and NSMR methods. The largest disadvantage of the prestressing system is that the system cannot be removed until the filler is cured. This problem lowers the turning rate of the equipment and makes it limited to experiment, which stresses the necessity of a new prestressing system. Therefore, the present study applies a new prestressing system which reliefs the need to wait until the curing of the filler after jacking to the prestressing of NSMR and examines the effect of the prestressing size and location of the anchorage on the strengthened behaviour. The experimental results show that the crack and yield loads increase with higher level of prestress, while the ductility tends to reduce, and the anchor plate should be installed within the effective depth ds to minimize the occurrence of shear-induced diagonal cracks. The comparison of the experimental results and results by section analysis shows that the section analysis could predict the maximum load of the specimens strengthened by prestressed NSMR within an error between 4% and 6%